FAP

DescriptionProlyl endopeptidase FAP

Gene and Protein Information

Gene ID2191
Uniprot Accession IDs O00199 Q53TP5 Q86Z29 Q99998 Q9UID4
Ensembl ID ENSP00000188790
Symbol FAPA SIMP DPPIV FAPalpha
FamilyBelongs to the peptidase S9B family.
Sequence
MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459691FAPfibroblast activation protein alpha9598VGNC:425OMA, EggNOG
Macaque701541FAPfibroblast activation protein alpha9544Inparanoid, OMA, EggNOG
Mouse14089Fapfibroblast activation protein10090MGI:109608Inparanoid, OMA, EggNOG
Dog608176FAPfibroblast activation protein alpha9615VGNC:40727Inparanoid, OMA, EggNOG
Horse100051480FAPfibroblast activation protein alpha9796VGNC:17908Inparanoid, OMA, EggNOG
Cow508882FAPfibroblast activation protein alpha9913VGNC:28862Inparanoid, OMA, EggNOG
Pig100736572FAPfibroblast activation protein alpha9823Inparanoid, OMA
Opossum100022372FAPfibroblast activation protein alpha13616Inparanoid, OMA, EggNOG
Platypus100082270FAPfibroblast activation protein alpha9258Inparanoid, OMA, EggNOG
Chicken424186FAPfibroblast activation protein alpha9031CGNC:8428Inparanoid, OMA
Anole lizard100553731fapfibroblast activation protein alpha28377Inparanoid, OMA
XenopusFAPfibroblast activation protein alpha [Source:HGNC Symbol;Acc:HGNC:3590]8364OMA, EggNOG
C. elegans180042dpf-1Dipeptidyl Peptidase Four (IV) family6239OMA, EggNOG
Fruitfly33810CG11034CG11034 gene product from transcript CG11034-RC7227FBgn0031741Inparanoid, EggNOG
S.cerevisiae856423DAP2Dap2p4932S000001070OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Prolyl endopeptidase FAP
protein    /    protease    /    Prolyl endopeptidase FAP
protein    /    enzyme modulator    /    Prolyl endopeptidase FAP
protein    /    hydrolase    /    Prolyl endopeptidase FAP
DTO Classes
protein    /    Enzyme    /    Protease    /    Serine protease    /    Prolyl endopeptidase FAP

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source