| Description | Thyrotropin receptor |
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Gene and Protein Information
| Gene ID | 7253 |
|---|---|
| Uniprot Accession IDs | A0PJU7 F5GYU5 G3V2A9 Q16503 Q8TB90 Q96GT6 Q9P1V4 Q9ULA3 Q9UPH3 |
| Ensembl ID | ENSP00000441235 |
| Symbol | LGR3 LGR3 CHNG1 hTSHR-I |
| Family | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. |
| Sequence | MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLDVSQTSVTALPSKGLEHLKELIARNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNESSMQSLRQRKSVNALNSPLHQEYEENLGDSIVGYKEKSKFQDTHNNAHYYVFFEEQEDEIIGFGQELKNPQEETLQAFDSHYDYTICGDSEDMVCTPKSDEFNPCEDIMGYKFLRIVVWFVSLLALLGNVFVLLILLTSHYKLNVPRFLMCNLAFADFCMGMYLLLIASVDLYTHSEYYNHAIDWQTGPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKIRLRHACAIMVGGWVCCFLLALLPLVGISSYAKVSICLPMDTETPLALAYIVFVLTLNIVAFVIVCCCYVKIYITVRNPQYNPGDKDTKIAKRMAVLIFTDFICMAPISFYALSAILNKPLITVSNSKILLVLFYPLNSCANPFLYAIFTKAFQRDVFILLSKFGICKRQAQAYRGQRVPPKNSTDIQVQKVTHDMRQGLHNMEDVYELIENSHLTPKKQGQISEEYMQTVL Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 453077 | TSHR | thyroid stimulating hormone receptor | 9598 | VGNC:3294 | OMA, EggNOG |
| Macaque | 574251 | TSHR | thyroid stimulating hormone receptor | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 22095 | Tshr | thyroid stimulating hormone receptor | 10090 | MGI:98849 | Inparanoid, OMA, EggNOG |
| Rat | 25360 | Tshr | thyroid stimulating hormone receptor | 10116 | RGD:3911 | Inparanoid, OMA, EggNOG |
| Dog | 403968 | TSHR | thyroid stimulating hormone receptor | 9615 | VGNC:47902 | Inparanoid, OMA, EggNOG |
| Horse | 100052603 | TSHR | thyroid stimulating hormone receptor | 9796 | VGNC:24581 | Inparanoid, OMA, EggNOG |
| Cow | 281553 | TSHR | thyroid stimulating hormone receptor | 9913 | VGNC:36419 | Inparanoid, OMA, EggNOG |
| Opossum | 100021427 | TSHR | thyroid stimulating hormone receptor | 13616 | Inparanoid, EggNOG | |
| Platypus | TSHR | thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373] | 9258 | OMA, EggNOG | ||
| Chicken | 428900 | TSHR | thyroid stimulating hormone receptor | 9031 | CGNC:8028 | Inparanoid, OMA |
| Anole lizard | 100565546 | tshr | thyroid stimulating hormone receptor | 28377 | Inparanoid, OMA | |
| Xenopus | 100492843 | tshr | thyroid stimulating hormone receptor | 8364 | XB-GENE-991483 | Inparanoid, OMA |
| Zebrafish | 560609 | tshr | thyroid stimulating hormone receptor | 7955 | ZDB-GENE-110524-4 | Inparanoid, OMA |
| C. elegans | 179381 | fshr-1 | FSHR (mammalian follicle stimulating hormone receptor) homolog | 6239 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / extracellular matrix protein / Thyrotropin receptor
protein / receptor / Thyrotropin receptor
protein / extracellular matrix protein / Thyrotropin receptor
protein / receptor / Thyrotropin receptor
DTO Classes
protein / G-protein coupled receptor / Class A rhodopsin like / Glycoprotein hormone receptor / Thyrotropin receptor
protein / G-protein coupled receptor / Class A rhodopsin like / Glycoprotein hormone receptor / Thyrotropin receptor
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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