TSHR

DescriptionThyrotropin receptor

Gene and Protein Information

Gene ID7253
Uniprot Accession IDs A0PJU7 F5GYU5 G3V2A9 Q16503 Q8TB90 Q96GT6 Q9P1V4 Q9ULA3 Q9UPH3
Ensembl ID ENSP00000441235
Symbol LGR3 LGR3 CHNG1 hTSHR-I
FamilyBelongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
Sequence
MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLDVSQTSVTALPSKGLEHLKELIARNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNESSMQSLRQRKSVNALNSPLHQEYEENLGDSIVGYKEKSKFQDTHNNAHYYVFFEEQEDEIIGFGQELKNPQEETLQAFDSHYDYTICGDSEDMVCTPKSDEFNPCEDIMGYKFLRIVVWFVSLLALLGNVFVLLILLTSHYKLNVPRFLMCNLAFADFCMGMYLLLIASVDLYTHSEYYNHAIDWQTGPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKIRLRHACAIMVGGWVCCFLLALLPLVGISSYAKVSICLPMDTETPLALAYIVFVLTLNIVAFVIVCCCYVKIYITVRNPQYNPGDKDTKIAKRMAVLIFTDFICMAPISFYALSAILNKPLITVSNSKILLVLFYPLNSCANPFLYAIFTKAFQRDVFILLSKFGICKRQAQAYRGQRVPPKNSTDIQVQKVTHDMRQGLHNMEDVYELIENSHLTPKKQGQISEEYMQTVL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp453077TSHRthyroid stimulating hormone receptor9598VGNC:3294OMA, EggNOG
Macaque574251TSHRthyroid stimulating hormone receptor9544Inparanoid, OMA, EggNOG
Mouse22095Tshrthyroid stimulating hormone receptor10090MGI:98849Inparanoid, OMA, EggNOG
Rat25360Tshrthyroid stimulating hormone receptor10116RGD:3911Inparanoid, OMA, EggNOG
Dog403968TSHRthyroid stimulating hormone receptor9615VGNC:47902Inparanoid, OMA, EggNOG
Horse100052603TSHRthyroid stimulating hormone receptor9796VGNC:24581Inparanoid, OMA, EggNOG
Cow281553TSHRthyroid stimulating hormone receptor9913VGNC:36419Inparanoid, OMA, EggNOG
Opossum100021427TSHRthyroid stimulating hormone receptor13616Inparanoid, EggNOG
PlatypusTSHRthyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373]9258OMA, EggNOG
Chicken428900TSHRthyroid stimulating hormone receptor9031CGNC:8028Inparanoid, OMA
Anole lizard100565546tshrthyroid stimulating hormone receptor28377Inparanoid, OMA
Xenopus100492843tshrthyroid stimulating hormone receptor8364XB-GENE-991483Inparanoid, OMA
Zebrafish560609tshrthyroid stimulating hormone receptor7955ZDB-GENE-110524-4Inparanoid, OMA
C. elegans179381fshr-1FSHR (mammalian follicle stimulating hormone receptor) homolog6239Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    extracellular matrix protein    /    Thyrotropin receptor
protein    /    receptor    /    Thyrotropin receptor
DTO Classes
protein    /    G-protein coupled receptor    /    Class A rhodopsin like    /    Glycoprotein hormone receptor    /    Thyrotropin receptor

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source