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PLK4

Description	Serine/threonine-protein kinase PLK4

Gene and Protein Information

Gene ID	10733
Uniprot Accession IDs	B2RAL0 B7Z837 B7Z8G7 Q8IYF0 Q96Q95 Q9UD84 Q9UDE2
Ensembl ID	ENSP00000270861
Symbol	SAK STK18 SAK STK18 MCCRP2
Family	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Sequence	MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	461480	PLK4	polo like kinase 4	9598	VGNC:7051	OMA, EggNOG
Macaque	710233	PLK4	polo like kinase 4	9544		Inparanoid, OMA, EggNOG
Mouse	20873	Plk4	polo like kinase 4	10090	MGI:101783	Inparanoid, OMA, EggNOG
Rat	310344	Plk4	polo-like kinase 4	10116	RGD:1305390	Inparanoid, OMA, EggNOG
Dog	476087	PLK4	polo like kinase 4	9615	VGNC:44698	Inparanoid, OMA, EggNOG
Horse	100063593	PLK4	polo like kinase 4	9796	VGNC:21582	Inparanoid, OMA, EggNOG
Cow	514405	PLK4	polo like kinase 4	9913	VGNC:33036	Inparanoid, OMA, EggNOG
Opossum	100010836	PLK4	polo like kinase 4	13616		Inparanoid, OMA, EggNOG
Chicken	422497	PLK4	polo like kinase 4	9031	CGNC:51756	OMA, EggNOG
Anole lizard	100557501	plk4	polo like kinase 4	28377		Inparanoid, OMA, EggNOG
Xenopus	100038180	plk4	polo like kinase 4	8364	XB-GENE-493608	Inparanoid, OMA, EggNOG
Zebrafish	368390	plk4	polo-like kinase 4 (Drosophila)	7955	ZDB-GENE-030619-14	Inparanoid, OMA, EggNOG
Fruitfly	40384	SAK	Sak kinase	7227	FBgn0026371	Inparanoid, OMA, EggNOG

DTO Classes
protein / Kinase / Protein kinase / Other group / PLK family / Serine/threonine-protein kinase plk4

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Name	Specifications	Species reactivity	species	Application	View Details

Name	Disease Type	Mondoid

Data Source	Name	Explore more targets	Explore in Source