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Protein or Target Summary

Serine/threonine-protein kinase PLK4

Gene ID10733
uniprotO00444
Gene NamePLK4
Ensernbl IDENSP00000270861
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Sequence
MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN10733PLK4Serine/threonine-protein kinase PLK4O00444
MOUSEPlk4Serine/threonine-protein kinase PLK4F6QIM3
MOUSEPlk4Serine/threonine-protein kinase PLK4E9PVH4
MOUSEPlk4Serine/threonine-protein kinase PLK4E9Q4W7
MOUSEPlk4Serine/threonine-protein kinase PLK4A0A0N4SWB8
MOUSEPlk4Uncharacterized proteinQ8C3W9
MOUSEPlk4MCG142332, isoform CRA_eQ3V382
MOUSE20873Plk4Serine/threonine-protein kinase PLK4Q64702
RAT310344Plk4Polo-like kinase 4 (Drosophila) (Predicted), isoform CRA_aA0A0G2JZ86
RAT310344Plk4Serine/threonine-protein kinase PLK4B2GUY1

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    PLK family    /    Serine/threonine-protein kinase plk4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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