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PLK4
Description | Serine/threonine-protein kinase PLK4 |
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Gene and Protein Information
Gene ID | 10733 |
Uniprot Accession IDs | B2RAL0 B7Z837 B7Z8G7 Q8IYF0 Q96Q95 Q9UD84 Q9UDE2 |
Ensembl ID | ENSP00000270861 |
Symbol | SAK STK18 SAK STK18 MCCRP2 |
Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. |
Sequence | MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH Show more |
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Homologous gene and protein info.
Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
Chimp | 461480 | PLK4 | polo like kinase 4 | 9598 | VGNC:7051 | OMA, EggNOG |
Macaque | 710233 | PLK4 | polo like kinase 4 | 9544 | | Inparanoid, OMA, EggNOG |
Mouse | 20873 | Plk4 | polo like kinase 4 | 10090 | MGI:101783 | Inparanoid, OMA, EggNOG |
Rat | 310344 | Plk4 | polo-like kinase 4 | 10116 | RGD:1305390 | Inparanoid, OMA, EggNOG |
Dog | 476087 | PLK4 | polo like kinase 4 | 9615 | VGNC:44698 | Inparanoid, OMA, EggNOG |
Horse | 100063593 | PLK4 | polo like kinase 4 | 9796 | VGNC:21582 | Inparanoid, OMA, EggNOG |
Cow | 514405 | PLK4 | polo like kinase 4 | 9913 | VGNC:33036 | Inparanoid, OMA, EggNOG |
Opossum | 100010836 | PLK4 | polo like kinase 4 | 13616 | | Inparanoid, OMA, EggNOG |
Chicken | 422497 | PLK4 | polo like kinase 4 | 9031 | CGNC:51756 | OMA, EggNOG |
Anole lizard | 100557501 | plk4 | polo like kinase 4 | 28377 | | Inparanoid, OMA, EggNOG |
Xenopus | 100038180 | plk4 | polo like kinase 4 | 8364 | XB-GENE-493608 | Inparanoid, OMA, EggNOG |
Zebrafish | 368390 | plk4 | polo-like kinase 4 (Drosophila) | 7955 | ZDB-GENE-030619-14 | Inparanoid, OMA, EggNOG |
Fruitfly | 40384 | SAK | Sak kinase | 7227 | FBgn0026371 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
Data Source | Name | Explore more targets | Explore in Source |
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