Gene Symbol: PRRC1 PPIs: Total high-confidence protein-protein interactions associated with this target.213 Associated antibodies: 0 Associated ligand: 0 | UniProt ID: Q96M27 PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.2.779227 Active quantity: 0 Associated recombinant protein: 0 | IDG Family: Other PubTator Score: A score derived from text mining PubMed data1.500000 |
Gene Symbol: PRPF3
PPIs: Total high-confidence protein-protein interactions associated with this target.989
Associated antibodies: 0
Associated ligand: 0
UniProt ID: O43395
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.78.251854
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data375.134570
Gene Symbol: PRPF4
PPIs: Total high-confidence protein-protein interactions associated with this target.1032
Associated antibodies: 1
Associated ligand: 1
UniProt ID: O43172
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.12.517487
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data10.757080
Gene Symbol: PRPH2
PPIs: Total high-confidence protein-protein interactions associated with this target.442
Associated antibodies: 0
Associated ligand: 0
UniProt ID: P23942
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.430.518925
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data544.861669
Gene Symbol: PROS1
PPIs: Total high-confidence protein-protein interactions associated with this target.488
Associated antibodies: 1
Associated ligand: 0
UniProt ID: P07225
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.677.925083
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data176.950659
Gene Symbol: CFP
PPIs: Total high-confidence protein-protein interactions associated with this target.1055
Associated antibodies: 0
Associated ligand: 0
UniProt ID: P27918
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.1596.960675
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data486.435911
Gene Symbol: OPRPN
PPIs: Total high-confidence protein-protein interactions associated with this target.138
Associated antibodies: 0
Associated ligand: 0
UniProt ID: Q99935
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.72.143338
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data42.634523
Gene Symbol: PROK1
PPIs: Total high-confidence protein-protein interactions associated with this target.320
Associated antibodies: 0
Associated ligand: 0
UniProt ID: P58294
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.116.244814
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data200.503095
Gene Symbol: PFN2
PPIs: Total high-confidence protein-protein interactions associated with this target.1061
Associated antibodies: 0
Associated ligand: 0
UniProt ID: P35080
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.245.940161
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data160.170212
Gene Symbol: PFN1
PPIs: Total high-confidence protein-protein interactions associated with this target.1004
Associated antibodies: 3
Associated ligand: 0
UniProt ID: P07737
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.275.465057
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data153.465711
Gene Symbol: PFN3
PPIs: Total high-confidence protein-protein interactions associated with this target.122
Associated antibodies: 0
Associated ligand: 0
UniProt ID: P60673
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.14.576999
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data3.824243
Gene Symbol: GRK1
PPIs: Total high-confidence protein-protein interactions associated with this target.602
Associated antibodies: 0
Associated ligand: 0
UniProt ID: Q15835
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.154.809260
Active quantity: 4
Associated recombinant protein: 0
IDG Family: Kinase
PubTator Score: A score derived from text mining PubMed data104.399204
Gene Symbol: PPM1D
PPIs: Total high-confidence protein-protein interactions associated with this target.1286
Associated antibodies: 0
Associated ligand: 0
UniProt ID: O15297
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.291.840029
Active quantity: 9
Associated recombinant protein: 0
IDG Family: phosphatase
PubTator Score: A score derived from text mining PubMed data158.725000
Gene Symbol: PPP1R3E
PPIs: Total high-confidence protein-protein interactions associated with this target.227
Associated antibodies: 0
Associated ligand: 0
UniProt ID: Q9H7J1
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.0.658648
Active quantity: 0
Associated recombinant protein: 0
IDG Family: phosphatase
PubTator Score: A score derived from text mining PubMed data1.000000
Gene Symbol: PPP1R21
PPIs: Total high-confidence protein-protein interactions associated with this target.151
Associated antibodies: 0
Associated ligand: 0
UniProt ID: Q6ZMI0
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.4.723011
Active quantity: 0
Associated recombinant protein: 0
IDG Family: phosphatase
PubTator Score: A score derived from text mining PubMed data1.293652
Gene Symbol: LGALS14
PPIs: Total high-confidence protein-protein interactions associated with this target.94
Associated antibodies: 0
Associated ligand: 0
UniProt ID: Q8TCE9
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.15.676803
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data4.827381
Gene Symbol: PRXL2C
PPIs: Total high-confidence protein-protein interactions associated with this target.173
Associated antibodies: 0
Associated ligand: 0
UniProt ID: Q7RTV5
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.1.851562
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data1.333333
Gene Symbol: PRXL2A
PPIs: Total high-confidence protein-protein interactions associated with this target.212
Associated antibodies: 0
Associated ligand: 1
UniProt ID: Q9BRX8
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.93.184952
Active quantity: 1
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data3.336602
Gene Symbol: PWWP2B
PPIs: Total high-confidence protein-protein interactions associated with this target.71
Associated antibodies: 0
Associated ligand: 0
UniProt ID: Q6NUJ5
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.2.506795
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data0.166666
Gene Symbol: PUM3
PPIs: Total high-confidence protein-protein interactions associated with this target.1117
Associated antibodies: 0
Associated ligand: 0
UniProt ID: Q15397
PubMed Score: Jensen Lab's fractional counting score indicating the prevalence of this target in PubMed articles.152.715884
Active quantity: 0
Associated recombinant protein: 0
IDG Family: Other
PubTator Score: A score derived from text mining PubMed data2622.624606
Shop By
options
pathway
- Signal Transduction 2484
- Immune System 2125
- Metabolism 2090
- Metabolism of proteins 2003
- Post-translational protein modification 1420
- Gene expression (Transcription) 1362
- RNA Polymerase II Transcription 1225
- Generic Transcription Pathway 1106
- Disease 1096
- Innate Immune System 1086
- Signaling by GPCR 998
- Developmental Biology 995
- GPCR downstream signalling 938
- Cytokine Signaling in Immune system 915
- Adaptive Immune System 800
- Metabolism of lipids 731
- Transport of small molecules 723
- Metabolism of RNA 677
- Vesicle-mediated transport 646
- Signaling by Interleukins 616
- Membrane Trafficking 606
- Cell Cycle 592
- Hemostasis 589
- Neutrophil degranulation 535
- Axon guidance 528
- Cell Cycle, Mitotic 490
- Cellular responses to external stimuli 480
- GPCR ligand binding 455
- Signaling by Receptor Tyrosine Kinases 455
- Class I MHC mediated antigen processing & presentation 432
- G alpha (i) signalling events 404
- Infectious disease 403
- Neuronal System 396
- Signaling by Rho GTPases 395
- Cellular responses to stress 388
- Diseases of signal transduction 387
- G alpha (s) signalling events 371
- Metabolism of amino acids and derivatives 368
- Transcriptional Regulation by TP53 363
- M Phase 345
- Class A/1 (Rhodopsin-like receptors) 320
- Intracellular signaling by second messengers 304
- Antigen processing: Ubiquitination & Proteasome degradation 303
- DNA Repair 303
- Extracellular matrix organization 297
- Signaling by WNT 296
- MAPK family signaling cascades 293
- Metabolism of carbohydrates 292
- Other interleukin signaling 287
- Asparagine N-linked glycosylation 286
- Translation 284
- Interferon Signaling 276
- Organelle biogenesis and maintenance 275
- Cell Cycle Checkpoints 270
- RHO GTPase Effectors 270
- PIP3 activates AKT signaling 265
- FLT3 Signaling 264
- Deubiquitination 260
- Platelet activation, signaling and aggregation 257
- HIV Infection 253
- Transmission across Chemical Synapses 253
- MAPK1/MAPK3 signaling 252
- SLC-mediated transmembrane transport 250
- RAF/MAP kinase cascade 246
- Processing of Capped Intron-Containing Pre-mRNA 239
- Chromatin modifying enzymes 234
- Chromatin organization 234
- Neddylation 230
- Signaling by Nuclear Receptors 230
- Olfactory Signaling Pathway 226
- G alpha (q) signalling events 217
- Biological oxidations 216
- Signaling by ROBO receptors 216
- rRNA processing 212
- Phospholipid metabolism 210
- Transcriptional regulation by RUNX1 205
- Signaling by NOTCH 203
- Muscle contraction 201
- TCF dependent signaling in response to WNT 201
- rRNA processing in the nucleus and cytosol 190
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 189
- Metabolism of vitamins and cofactors 188
- ESR-mediated signaling 187
- Peptide ligand-binding receptors 187
- Ub-specific processing proteases 187
- Cilium Assembly 186
- Intra-Golgi and retrograde Golgi-to-ER traffic 186
- Neurotransmitter receptors and postsynaptic signal transmission 186
- mRNA Splicing 186
- Mitotic G2-G2/M phases 184
- Mitotic Metaphase and Anaphase 183
- G2/M Transition 182
- Mitotic Anaphase 182
- Major pathway of rRNA processing in the nucleolus and cytosol 180
- Mitotic Prometaphase 180
- Programmed Cell Death 179
- mRNA Splicing - Major Pathway 179
- Disorders of transmembrane transporters 178
- Ion channel transport 178
- Apoptosis 176
- SUMOylation 175
- The citric acid (TCA) cycle and respiratory electron transport 173
- Fatty acid metabolism 172
- Regulation of expression of SLITs and ROBOs 171
- Separation of Sister Chromatids 170
- SUMO E3 ligases SUMOylate target proteins 169
- Antigen processing-Cross presentation 168
- Interferon gamma signaling 168
- Transport to the Golgi and subsequent modification 167
- Keratinization 165
- Protein localization 165
- S Phase 162
- Cellular Senescence 161
- Regulation of TP53 Activity 160
- Influenza Infection 155
- Host Interactions of HIV factors 153
- ER-Phagosome pathway 152
- Metabolism of steroids 151
- Mitotic G1-G1/S phases 151
- HIV Life Cycle 150
- Toll-like Receptor Cascades 150
- G2/M Checkpoints 149
- Beta-catenin independent WNT signaling 146
- DNA Double-Strand Break Repair 145
- Influenza Life Cycle 144
- Clathrin-mediated endocytosis 143
- Diseases of glycosylation 142
- C-type lectin receptors (CLRs) 141
- Signaling by Hedgehog 141
- Interleukin-1 family signaling 140
- PTEN Regulation 140
- Death Receptor Signalling 138
- Factors involved in megakaryocyte development and platelet production 138
- Cardiac conduction 137
- Cell surface interactions at the vascular wall 137
- Late Phase of HIV Life Cycle 137
- ER to Golgi Anterograde Transport 136
- Influenza Viral RNA Transcription and Replication 135
- Interferon alpha/beta signaling 135
- Rho GTPase cycle 135
- Fc epsilon receptor (FCERI) signaling 134
- G1/S Transition 132
- Response to elevated platelet cytosolic Ca2+ 132
- Protein ubiquitination 130
- DNA Replication 128
- Glycerophospholipid biosynthesis 128
- TCR signaling 128
- Platelet degranulation 127
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 124
- Toll Like Receptor 4 (TLR4) Cascade 124
- Metabolism of water-soluble vitamins and cofactors 122
- Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 122
- Cell-Cell communication 121
- Glycosaminoglycan metabolism 121
- Transcriptional regulation by RUNX2 121
- Synthesis of DNA 120
- Cap-dependent Translation Initiation 119
- Eukaryotic Translation Initiation 119
- RHO GTPases Activate Formins 119
- Rab regulation of trafficking 119
- Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 119
- tRNA processing 119
- MHC class II antigen presentation 118
- Estrogen-dependent gene expression 117
- Homology Directed Repair 117
- PPARA activates gene expression 117
- Selenoamino acid metabolism 117
- Epigenetic regulation of gene expression 116
- Golgi-to-ER retrograde transport 116
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 115
- Nonsense-Mediated Decay (NMD) 115
- Signaling by the B Cell Receptor (BCR) 113
- GTP hydrolysis and joining of the 60S ribosomal subunit 112
- Reproduction 112
- SRP-dependent cotranslational protein targeting to membrane 112
- Degradation of the extracellular matrix 111
- HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 111
- Integration of energy metabolism 111
- L13a-mediated translational silencing of Ceruloplasmin expression 111
- Mitotic Prophase 111
- E3 ubiquitin ligases ubiquitinate target proteins 110
- Negative regulation of the PI3K/AKT network 110
- O-linked glycosylation 110
- Nucleotide Excision Repair 109
- Downstream TCR signaling 108
- Interleukin-4 and Interleukin-13 signaling 108
- Mitotic Spindle Checkpoint 108
- Post-translational protein phosphorylation 107
- Autophagy 106
- HATs acetylate histones 106
- Transport of inorganic cations/anions and amino acids/oligopeptides 106
- Cargo recognition for clathrin-mediated endocytosis 105
- Phase I - Functionalization of compounds 105
- Phase II - Conjugation of compounds 105
- Resolution of Sister Chromatid Cohesion 105
- ABC-family proteins mediated transport 104
- Gene Silencing by RNA 104
- Hedgehog 'off' state 104
- Diseases of metabolism 103
- Interleukin-1 signaling 103
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 103
- Signaling by VEGF 103
- PI3K/AKT Signaling in Cancer 102
- Signaling by TGF-beta family members 102
- CLEC7A (Dectin-1) signaling 101
- Formation of a pool of free 40S subunits 101
- Stimuli-sensing channels 101
- TNFR2 non-canonical NF-kB pathway 101
- L1CAM interactions 100
- Protein folding 100
- Respiratory electron transport 100
- SLC transporter disorders 100
- Cellular response to heat stress 99
- Potassium Channels 99
- Signaling by NTRKs 99
- Visual phototransduction 99
- Metabolism of nucleotides 98
- RUNX1 regulates transcription of genes involved in differentiation of HSCs 98
- Transcriptional regulation by RUNX3 98
- Anchoring of the basal body to the plasma membrane 97
- Class B/2 (Secretin family receptors) 96
- MyD88-independent TLR4 cascade 96
- TRIF(TICAM1)-mediated TLR4 signaling 96
- UCH proteinases 96
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane 95
- Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 95
- Toll Like Receptor 2 (TLR2) Cascade 95
- Toll Like Receptor TLR1:TLR2 Cascade 95
- Toll Like Receptor TLR6:TLR2 Cascade 95
- VEGFA-VEGFR2 Pathway 95
- Chaperonin-mediated protein folding 94
- Toll Like Receptor 9 (TLR9) Cascade 94
- p75 NTR receptor-mediated signalling 94
- Eukaryotic Translation Elongation 93
- Eukaryotic Translation Termination 93
- PCP/CE pathway 93
- Post-translational modification: synthesis of GPI-anchored proteins 93
- Selenocysteine synthesis 93
- Toll Like Receptor 3 (TLR3) Cascade 93
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 92
- Amplification of signal from the kinetochores 92
- EPH-Ephrin signaling 92
- Glucose metabolism 92
- MAPK6/MAPK4 signaling 92
- Regulation of TP53 Activity through Phosphorylation 92
- Unfolded Protein Response (UPR) 92
- Antigen Presentation: Folding, assembly and peptide loading of class I MHC 91
- Oxidative Stress Induced Senescence 91
- Switching of origins to a post-replicative state 91
- Collagen formation 90
- MyD88 dependent cascade initiated on endosome 90
- Regulation of mRNA stability by proteins that bind AU-rich elements 90
- Toll Like Receptor 7/8 (TLR7/8) Cascade 90
- Mitochondrial biogenesis 89
- Opioid Signalling 89
- Peptide chain elongation 89
- Protein-protein interactions at synapses 89
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 89
- Viral mRNA Translation 89
- Activation of HOX genes during differentiation 88
- Activation of anterior HOX genes in hindbrain development during early embryogenesis 88
- Cell junction organization 88
- Fcgamma receptor (FCGR) dependent phagocytosis 88
- Peptide hormone metabolism 88
- Sphingolipid metabolism 88
- APC/C-mediated degradation of cell cycle proteins 87
- DAP12 interactions 87
- Hedgehog 'on' state 87
- Macroautophagy 87
- Platelet homeostasis 87
- RAB GEFs exchange GTP for GDP on RABs 87
- Regulation of PLK1 Activity at G2/M Transition 87
- Regulation of mitotic cell cycle 87
- Signaling by FGFR 87
- Chromosome Maintenance 86
- Cyclin A:Cdk2-associated events at S phase entry 86
- DNA Replication Pre-Initiation 86
- Meiosis 86
- Mitochondrial translation 86
- TP53 Regulates Metabolic Genes 86
- Transport of bile salts and organic acids, metal ions and amine compounds 86
- Degradation of beta-catenin by the destruction complex 85
- Cyclin E associated events during G1/S transition 84
- Global Genome Nucleotide Excision Repair (GG-NER) 84
- MyD88 cascade initiated on plasma membrane 84
- Toll Like Receptor 10 (TLR10) Cascade 84
- Toll Like Receptor 5 (TLR5) Cascade 84
- Transcriptional regulation of white adipocyte differentiation 84
- COPI-mediated anterograde transport 83
- PI Metabolism 83
- Signaling by NOTCH4 83
- Transport of Mature Transcript to Cytoplasm 83
- Antiviral mechanism by IFN-stimulated genes 82
- COPI-dependent Golgi-to-ER retrograde traffic 82
- Downstream signaling events of B Cell Receptor (BCR) 82
- RNA Polymerase II Pre-transcription Events 82
- FCERI mediated NF-kB activation 81
- Regulation of APC/C activators between G1/S and early anaphase 81
- Regulation of HSF1-mediated heat shock response 81
- Regulation of insulin secretion 81
- Antimicrobial peptides 80
- Mitochondrial translation elongation 80
- Mitochondrial translation initiation 80
- Mitochondrial translation termination 80
- Centrosome maturation 79
- Costimulation by the CD28 family 79
- Oncogenic MAPK signaling 79
- Recruitment of mitotic centrosome proteins and complexes 79
- ABC transporter disorders 78
- Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 78
- Endosomal/Vacuolar pathway 78
- Processing of DNA double-strand break ends 78
- RNA Polymerase I Promoter Clearance 78
- RNA Polymerase I Transcription 78
- Recruitment of NuMA to mitotic centrosomes 78
- Senescence-Associated Secretory Phenotype (SASP) 78
- Signaling by Insulin receptor 78
- Signaling by NTRK1 (TRKA) 78
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 77
- DDX58/IFIH1-mediated induction of interferon-alpha/beta 77
- G alpha (12/13) signalling events 77
- Negative epigenetic regulation of rRNA expression 77
- SUMOylation of DNA damage response and repair proteins 77
- Transcription-Coupled Nucleotide Excision Repair (TC-NER) 77
- APC/C:Cdc20 mediated degradation of mitotic proteins 76
- Amyloid fiber formation 76
- Cellular response to hypoxia 76
- Pre-NOTCH Expression and Processing 76
- Constitutive Signaling by Aberrant PI3K in Cancer 75
- G2/M DNA damage checkpoint 75
- APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 74
- Activation of NMDA receptors and postsynaptic events 74
- Extra-nuclear estrogen signaling 74
- ISG15 antiviral mechanism 74
- NoRC negatively regulates rRNA expression 74
- Positive epigenetic regulation of rRNA expression 74
- Regulation of RUNX2 expression and activity 74
- Transcriptional regulation by small RNAs 74
- Transport of Mature mRNA derived from an Intron-Containing Transcript 74
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 73
- CDK-mediated phosphorylation and removal of Cdc6 73
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A 73
- Cell death signalling via NRAGE, NRIF and NADE 73
- Signaling by FGFR2 73
- Signaling by NOTCH1 73
- Signaling by TGF-beta Receptor Complex 73
- AURKA Activation by TPX2 72
- Formation of the cornified envelope 72
- Glycolysis 72
- Orc1 removal from chromatin 72
- Transcription of the HIV genome 72
- trans-Golgi Network Vesicle Budding 72
- Interleukin-17 signaling 71
- Plasma lipoprotein assembly, remodeling, and clearance 71
- RNA polymerase II transcribes snRNA genes 71
- Base Excision Repair 70
- Regulation of PTEN stability and activity 70
- Assembly of the pre-replicative complex 69
- Circadian Clock 69
- G1/S DNA Damage Checkpoints 69
- Loss of Nlp from mitotic centrosomes 69
- Loss of proteins required for interphase microtubule organization from the centrosome 69
- Regulation of RAS by GAPs 69
- APC/C:Cdc20 mediated degradation of Securin 68
- Activation of NF-kappaB in B cells 68
- COPII-mediated vesicle transport 68
- FOXO-mediated transcription 68
- Collagen biosynthesis and modifying enzymes 67
- Diseases associated with O-glycosylation of proteins 67
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 67
- Signaling by MET 67
- p53-Dependent G1 DNA Damage Response 67
- p53-Dependent G1/S DNA damage checkpoint 67
- HDR through Homologous Recombination (HRR) 66
- Hedgehog ligand biogenesis 66
- Integrin cell surface interactions 66
- RAB geranylgeranylation 66
- RNA Polymerase II Transcription Termination 66
- Asymmetric localization of PCP proteins 65
- Cytochrome P450 - arranged by substrate type 65
- Mitochondrial protein import 65
- Autodegradation of Cdh1 by Cdh1:APC/C 64
- Dual incision in TC-NER 64
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 64
- Semaphorin interactions 64
- Signaling by FGFR in disease 64
- Cell-cell junction organization 63
- Cytosolic sensors of pathogen-associated DNA 63
- Dectin-1 mediated noncanonical NF-kB signaling 63
- Gap-filling DNA repair synthesis and ligation in TC-NER 63
- MAP kinase activation 63
- Peroxisomal protein import 63
- Regulation of actin dynamics for phagocytic cup formation 63
- Signaling by BRAF and RAF fusions 63
- Synthesis of substrates in N-glycan biosythesis 63
- TP53 Regulates Transcription of DNA Repair Genes 63
- Defective CFTR causes cystic fibrosis 62
- O-linked glycosylation of mucins 62
- Post NMDA receptor activation events 62
- Ca2+ pathway 61
- Degradation of GLI1 by the proteasome 61
- Degradation of GLI2 by the proteasome 61
- GLI3 is processed to GLI3R by the proteasome 61
- RHO GTPases activate PKNs 61
- SCF(Skp2)-mediated degradation of p27/p21 61
- Telomere Maintenance 61
- The role of GTSE1 in G2/M progression after G2 checkpoint 61
- Transcriptional Regulation by MECP2 61
- CDT1 association with the CDC6:ORC:origin complex 60
- Hh mutants abrogate ligand secretion 60
- Metabolism of polyamines 60
- NIK-->noncanonical NF-kB signaling 60
- Pre-NOTCH Transcription and Translation 60
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59
- B-WICH complex positively regulates rRNA expression 59
- DNA Damage/Telomere Stress Induced Senescence 59
- Formation of RNA Pol II elongation complex 59
- Formation of the beta-catenin:TCF transactivating complex 59
- HDACs deacetylate histones 59
- Iron uptake and transport 59
- NCAM signaling for neurite out-growth 59
- RNA Polymerase I Promoter Escape 59
- RNA Polymerase II Transcription Elongation 59
- Regulation of PTEN gene transcription 59
- Arachidonic acid metabolism 58
- Complement cascade 58
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 58
- Constitutive Signaling by NOTCH1 PEST Domain Mutants 58
- Degradation of DVL 58
- Meiotic synapsis 58
- Neurexins and neuroligins 58
- Ribosomal scanning and start codon recognition 58
- Signaling by ERBB4 58
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 58
- Signaling by NOTCH1 PEST Domain Mutants in Cancer 58
- Signaling by NOTCH1 in Cancer 58
- Stabilization of p53 58
- Translation initiation complex formation 58
- rRNA modification in the nucleus and cytosol 58
- tRNA processing in the nucleus 58
- Assembly of collagen fibrils and other multimeric structures 57
- DNA Double Strand Break Response 57
- Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 57
- Regulation of RUNX3 expression and activity 57
- SUMOylation of chromatin organization proteins 57
- Transcriptional regulation of granulopoiesis 57
- mRNA 3'-end processing 57
- AUF1 (hnRNP D0) binds and destabilizes mRNA 56
- Degradation of AXIN 56
- ECM proteoglycans 56
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 56
- GABA receptor activation 56
- Golgi Associated Vesicle Biogenesis 56
- Interleukin-12 family signaling 56
- NRAGE signals death through JNK 56
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 56
- SCF-beta-TrCP mediated degradation of Emi1 56
- Signaling by RAS mutants 56
- Aquaporin-mediated transport 55
- Complex I biogenesis 55
- Ion transport by P-type ATPases 55
- Negative regulation of NOTCH4 signaling 55
- Pyruvate metabolism and Citric Acid (TCA) cycle 55
- Regulation of cholesterol biosynthesis by SREBP (SREBF) 55
- Vif-mediated degradation of APOBEC3G 55
- Insulin receptor signalling cascade 54
- Meiotic recombination 54
- Nuclear Envelope Breakdown 54
- Regulation of Apoptosis 54
- Signaling by Non-Receptor Tyrosine Kinases 54
- Signaling by PTK6 54
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 54
- Deadenylation-dependent mRNA decay 53
- G-protein mediated events 53
- Heparan sulfate/heparin (HS-GAG) metabolism 53
- IGF1R signaling cascade 53
- Metabolism of non-coding RNA 53
- Nuclear Receptor transcription pathway 53
- Signaling by PDGF 53
- Synthesis of PIPs at the plasma membrane 53
- Transcriptional activation of mitochondrial biogenesis 53
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 53
- Ubiquitin-dependent degradation of Cyclin D 53
- Vpu mediated degradation of CD4 53
- p53-Independent DNA Damage Response 53
- p53-Independent G1/S DNA damage checkpoint 53
- snRNP Assembly 53
- Apoptotic execution phase 52
- Autodegradation of the E3 ubiquitin ligase COP1 52
- Formation of TC-NER Pre-Incision Complex 52
- IRS-related events triggered by IGF1R 52
- Intrinsic Pathway for Apoptosis 52
- Ion homeostasis 52
- PLC beta mediated events 52
- Regulation of ornithine decarboxylase (ODC) 52
- Cargo trafficking to the periciliary membrane 51
- Cross-presentation of soluble exogenous antigens (endosomes) 51
- Formation of the ternary complex, and subsequently, the 43S complex 51
- G alpha (z) signalling events 51
- Neurotransmitter release cycle 51
- Regulation of activated PAK-2p34 by proteasome mediated degradation 51
- Translocation of SLC2A4 (GLUT4) to the plasma membrane 51
- mRNA Splicing - Minor Pathway 51
- Chondroitin sulfate/dermatan sulfate metabolism 50
- Deposition of new CENPA-containing nucleosomes at the centromere 50
- IRE1alpha activates chaperones 50
- Nucleosome assembly 50
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 50
- Signaling by ERBB2 50
- Signaling by FGFR1 50
- EPH-ephrin mediated repulsion of cells 49
- Netrin-1 signaling 49
- Nonhomologous End-Joining (NHEJ) 49
- Retrograde transport at the Trans-Golgi-Network 49
- Signaling by EGFR 49
- Signaling by NOTCH3 49
- Chemokine receptors bind chemokines 48
- IRS-mediated signalling 48
- Inositol phosphate metabolism 48
- Metabolism of fat-soluble vitamins 48
- RNA Polymerase I Transcription Initiation 48
- TP53 Regulates Transcription of Cell Cycle Genes 48
- The role of Nef in HIV-1 replication and disease pathogenesis 48
- XBP1(S) activates chaperone genes 48
- DNA Damage Bypass 47
- HIV Transcription Initiation 47
- NOTCH1 Intracellular Domain Regulates Transcription 47
- PKMTs methylate histone lysines 47
- RMTs methylate histone arginines 47
- RNA Polymerase II HIV Promoter Escape 47
- RNA Polymerase II Promoter Escape 47
- RNA Polymerase II Transcription Initiation 47
- RNA Polymerase II Transcription Initiation And Promoter Clearance 47
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47
- Regulation of Complement cascade 47
- Formation of HIV elongation complex in the absence of HIV Tat 46
- Interleukin-12 signaling 46
- SUMOylation of DNA replication proteins 46
- SUMOylation of RNA binding proteins 46
- Vasopressin regulates renal water homeostasis via Aquaporins 46
- Cyclin D associated events in G1 45
- Formation of HIV-1 elongation complex containing HIV-1 Tat 45
- G1 Phase 45
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 45
- HIV Transcription Elongation 45
- Interleukin-10 signaling 45
- Intra-Golgi traffic 45
- TP53 Regulates Transcription of Cell Death Genes 45
- Tat-mediated elongation of the HIV-1 transcript 45
- Collagen chain trimerization 44
- Glycosphingolipid metabolism 44
- Interleukin-2 family signaling 44
- Interleukin-3, Interleukin-5 and GM-CSF signaling 44
- PI3K Cascade 44
- Phase 0 - rapid depolarisation 44
- Retinoid metabolism and transport 44
- Sphingolipid de novo biosynthesis 44
- TBC/RABGAPs 44
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 44
- Transport of vitamins, nucleosides, and related molecules 44
- Viral Messenger RNA Synthesis 44
- Bile acid and bile salt metabolism 43
- Binding and Uptake of Ligands by Scavenger Receptors 43
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 43
- Formation of Incision Complex in GG-NER 43
- Host Interactions with Influenza Factors 43
- Kinesins 43
- Non-integrin membrane-ECM interactions 43
- Paradoxical activation of RAF signaling by kinase inactive BRAF 43
- SUMOylation of transcription cofactors 43
- Signaling by FGFR2 in disease 43
- Signaling by Retinoic Acid 43
- Signaling by SCF-KIT 43
- Signaling by moderate kinase activity BRAF mutants 43
- TNF signaling 43
- Transport of Mature mRNAs Derived from Intronless Transcripts 43
- Voltage gated Potassium channels 43
- Activation of gene expression by SREBF (SREBP) 42
- Amine ligand-binding receptors 42
- Base-Excision Repair, AP Site Formation 42
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 42
- Generation of second messenger molecules 42
- Homologous DNA Pairing and Strand Exchange 42
- Regulation of beta-cell development 42
- Transport of Mature mRNA Derived from an Intronless Transcript 42
- tRNA Aminoacylation 42
- Condensation of Prophase Chromosomes 41
- Deactivation of the beta-catenin transactivating complex 41
- Diseases associated with glycosaminoglycan metabolism 41
- Dual Incision in GG-NER 41
- Elastic fibre formation 41
- NS1 Mediated Effects on Host Pathways 41
- Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 41
- RNA Polymerase III Abortive And Retractive Initiation 41
- RNA Polymerase III Transcription 41
- Signaling by FGFR4 41
- tRNA modification in the nucleus and cytosol 41
- Cleavage of the damaged pyrimidine 40
- Collagen degradation 40
- DAG and IP3 signaling 40
- Depyrimidination 40
- Intraflagellar transport 40
- Negative regulation of MAPK pathway 40
- PRC2 methylates histones and DNA 40
- RET signaling 40
- Recognition and association of DNA glycosylase with site containing an affected pyrimidine 40
- Signaling by FGFR3 40
- Activation of GABAB receptors 39
- Class C/3 (Metabotropic glutamate/pheromone receptors) 39
- Formation of Fibrin Clot (Clotting Cascade) 39
- GABA B receptor activation 39
- Gamma carboxylation, hypusine formation and arylsulfatase activation 39
- Presynaptic phase of homologous DNA pairing and strand exchange 39
- SUMOylation of ubiquitinylation proteins 39
- Signaling by FGFR1 in disease 39
- Synthesis of PA 39
- mTOR signalling 39
- Apoptotic cleavage of cellular proteins 38
- Association of TriC/CCT with target proteins during biosynthesis 38
- DNA Damage Recognition in GG-NER 38
- HSP90 chaperone cycle for steroid hormone receptors (SHR) 38
- MAP2K and MAPK activation 38
- NCAM1 interactions 38
- O-glycosylation of TSR domain-containing proteins 38
- Ovarian tumor domain proteases 38
- Regulation of TP53 Expression and Degradation 38
- Resolution of Abasic Sites (AP sites) 38
- Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 38
- Activation of ATR in response to replication stress 37
- Defective B3GALTL causes Peters-plus syndrome (PpS) 37
- Defensins 37
- Detoxification of Reactive Oxygen Species 37
- Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 37
- HDR through Single Strand Annealing (SSA) 37
- Interactions of Rev with host cellular proteins 37
- Interactions of Vpr with host cellular proteins 37
- Platelet Aggregation (Plug Formation) 37
- Regulation of TP53 Degradation 37
- Triglyceride metabolism 37
- Ca-dependent events 36
- Carboxyterminal post-translational modifications of tubulin 36
- Fanconi Anemia Pathway 36
- Fatty acyl-CoA biosynthesis 36
- Glucagon signaling in metabolic regulation 36
- Glucagon-type ligand receptors 36
- HSF1-dependent transactivation 36
- Metabolic disorders of biological oxidation enzymes 36
- Nuclear Pore Complex (NPC) Disassembly 36
- RHO GTPases Activate WASPs and WAVEs 36
- RNA Polymerase III Transcription Initiation 36
- ROS and RNS production in phagocytes 36
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 36
- Smooth Muscle Contraction 36
- Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 36
- Transport of the SLBP Dependant Mature mRNA 36
- Cleavage of the damaged purine 35
- Depurination 35
- Diseases of carbohydrate metabolism 35
- Lysosome Vesicle Biogenesis 35
- Metabolism of steroid hormones 35
- Mitochondrial Fatty Acid Beta-Oxidation 35
- N-glycan trimming in the ER and Calnexin/Calreticulin cycle 35
- Nucleobase catabolism 35
- Recognition and association of DNA glycosylase with site containing an affected purine 35
- Rev-mediated nuclear export of HIV RNA 35
- SIRT1 negatively regulates rRNA expression 35
- SUMOylation of SUMOylation proteins 35
- Transport of the SLBP independent Mature mRNA 35
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 34
- COPI-independent Golgi-to-ER retrograde traffic 34
- CaM pathway 34
- Calmodulin induced events 34
- EPHB-mediated forward signaling 34
- Gluconeogenesis 34
- Glutathione conjugation 34
- HIV elongation arrest and recovery 34
- Negative regulation of FGFR2 signaling 34
- Negative regulators of DDX58/IFIH1 signaling 34
- Nuclear import of Rev protein 34
- Oncogene Induced Senescence 34
- Pausing and recovery of HIV elongation 34
- Signaling by WNT in cancer 34
- Signaling by high-kinase activity BRAF mutants 34
- Striated Muscle Contraction 34
- Synthesis of bile acids and bile salts 34
- Vpr-mediated nuclear import of PICs 34
- Activation of Matrix Metalloproteinases 33
- Activation of the pre-replicative complex 33
- Amino acid transport across the plasma membrane 33
- CD28 co-stimulation 33
- Cargo concentration in the ER 33
- Export of Viral Ribonucleoproteins from Nucleus 33
- FGFR2 mutant receptor activation 33
- Formation of the Early Elongation Complex 33
- Formation of the HIV-1 Early Elongation Complex 33
- Negative regulation of FGFR1 signaling 33
- PD-1 signaling 33
- Pausing and recovery of Tat-mediated HIV elongation 33
- Plasma lipoprotein clearance 33
- Regulation of TNFR1 signaling 33
- Resolution of D-Loop Structures 33
- Sialic acid metabolism 33
- Signaling by NOTCH2 33
- Tat-mediated HIV elongation arrest and recovery 33
- The phototransduction cascade 33
- Transcriptional Regulation by E2F6 33
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 32
- Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 32
- DNA methylation 32
- DNA strand elongation 32
- Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 32
- FGFR1 mutant receptor activation 32
- G-protein beta:gamma signalling 32
- GPVI-mediated activation cascade 32
- Inactivation, recovery and regulation of the phototransduction cascade 32
- Keratan sulfate/keratin metabolism 32
- NEP/NS2 Interacts with the Cellular Export Machinery 32
- Nuclear signaling by ERBB4 32
- PERK regulates gene expression 32
- Phosphorylation of CD3 and TCR zeta chains 32
- Plasma lipoprotein remodeling 32
- Regulation of Glucokinase by Glucokinase Regulatory Protein 32
- Resolution of D-loop Structures through Holliday Junction Intermediates 32
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 32
- Signal amplification 32
- Signalling to ERKs 32
- TGF-beta receptor signaling activates SMADs 32
- Termination of translesion DNA synthesis 32
- Thrombin signalling through proteinase activated receptors (PARs) 32
- Transport of Ribonucleoproteins into the Host Nucleus 32
- Activated NOTCH1 Transmits Signal to the Nucleus 31
- Activation of BH3-only proteins 31
- Adherens junctions interactions 31
- Disassembly of the destruction complex and recruitment of AXIN to the membrane 31
- Downstream signaling of activated FGFR1 31
- EGFR downregulation 31
- FCERI mediated MAPK activation 31
- Glutamate binding, activation of AMPA receptors and synaptic plasticity 31
- Glyoxylate metabolism and glycine degradation 31
- HS-GAG biosynthesis 31
- Inwardly rectifying K+ channels 31
- MAPK targets/ Nuclear events mediated by MAP kinases 31
- NOD1/2 Signaling Pathway 31
- Negative regulation of FGFR4 signaling 31
- Nicotinate metabolism 31
- Packaging Of Telomere Ends 31
- Pyruvate metabolism 31
- RNA Polymerase I Transcription Termination 31
- RUNX2 regulates bone development 31
- Regulation of MECP2 expression and activity 31
- Trafficking of AMPA receptors 31
- Transcriptional regulation of pluripotent stem cells 31
- Transferrin endocytosis and recycling 31
- Activation of kainate receptors upon glutamate binding 30
- Downstream signaling of activated FGFR2 30
- Endosomal Sorting Complex Required For Transport (ESCRT) 30
- Extension of Telomeres 30
- FCERI mediated Ca+2 mobilization 30
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 30
- Gap junction trafficking and regulation 30
- Molecules associated with elastic fibres 30
- Nef mediated downregulation of MHC class I complex cell surface expression 30
- RAF activation 30
- RNA Polymerase I Promoter Opening 30
- Recognition of DNA damage by PCNA-containing replication complex 30
- SUMOylation of intracellular receptors 30
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes 30
- Tight junction interactions 30
- Acyl chain remodelling of PE 29
- DAP12 signaling 29
- Downregulation of ERBB2 signaling 29
- Downstream signal transduction 29
- G1/S-Specific Transcription 29
- HSF1 activation 29
- Interaction between L1 and Ankyrins 29
- Interconversion of nucleotide di- and triphosphates 29
- MET promotes cell motility 29
- Myogenesis 29
- Negative regulation of FGFR3 signaling 29
- PIWI-interacting RNA (piRNA) biogenesis 29
- Peroxisomal lipid metabolism 29
- Regulation of TP53 Activity through Acetylation 29
- Surfactant metabolism 29
- Translocation of ZAP-70 to Immunological synapse 29
- Uptake and actions of bacterial toxins 29
- mRNA Capping 29
- Adrenaline,noradrenaline inhibits insulin secretion 28
- Beta defensins 28
- CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 28
- Cristae formation 28
- Energy dependent regulation of mTOR by LKB1-AMPK 28
- G-protein activation 28
- Gap junction trafficking 28
- Glycogen metabolism 28
- Keratan sulfate biosynthesis 28
- Mitophagy 28
- Notch-HLH transcription pathway 28
- Platelet calcium homeostasis 28
- Prefoldin mediated transfer of substrate to CCT/TriC 28
- Processing of Capped Intronless Pre-mRNA 28
- RNA Polymerase III Transcription Initiation From Type 1 Promoter 28
- RNA Polymerase III Transcription Initiation From Type 3 Promoter 28
- Recycling pathway of L1 28
- Signaling by BMP 28
- Synthesis of PC 28
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex 28
- TNFs bind their physiological receptors 28
- TRAF6 mediated IRF7 activation 28
- ATF4 activates genes in response to endoplasmic reticulum stress 27
- Acyl chain remodelling of PC 27
- BMAL1:CLOCK,NPAS2 activates circadian gene expression 27
- Budding and maturation of HIV virion 27
- Downstream signaling of activated FGFR4 27
- Effects of PIP2 hydrolysis 27
- Endogenous sterols 27
- G0 and Early G1 27
- Insulin processing 27
- Integrin alphaIIb beta3 signaling 27
- Integrin signaling 27
- Interleukin receptor SHC signaling 27
- Metalloprotease DUBs 27
- Microautophagy 27
- Phase 2 - plateau phase 27
- RNA Pol II CTD phosphorylation and interaction with CE 27
- RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27
- RNA Polymerase III Transcription Initiation From Type 2 Promoter 27
- Role of phospholipids in phagocytosis 27
- Sulfur amino acid metabolism 27
- VEGFR2 mediated vascular permeability 27
- A tetrasaccharide linker sequence is required for GAG synthesis 26
- Attenuation phase 26
- Calnexin/calreticulin cycle 26
- Constitutive Signaling by AKT1 E17K in Cancer 26
- Dectin-2 family 26
- Downregulation of TGF-beta receptor signaling 26
- FGFR2 alternative splicing 26
- Fertilization 26
- Insulin receptor recycling 26
- Interleukin-20 family signaling 26
- Metal ion SLC transporters 26
- N-glycan antennae elongation in the medial/trans-Golgi 26
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 26
- Synthesis of IP3 and IP4 in the cytosol 26
- TNFR1-induced NFkappaB signaling pathway 26
- WNT ligand biogenesis and trafficking 26
- ADP signalling through P2Y purinoceptor 1 25
- APC-Cdc20 mediated degradation of Nek2A 25
- Activation of G protein gated Potassium channels 25
- Basigin interactions 25
- Caspase activation via extrinsic apoptotic signalling pathway 25
- Cholesterol biosynthesis 25
- Cyclin A/B1/B2 associated events during G2/M transition 25
- Digestion and absorption 25
- Diseases associated with the TLR signaling cascade 25
- Diseases of Immune System 25
- Downstream signaling of activated FGFR3 25
- FRS-mediated FGFR2 signaling 25
- Formation of tubulin folding intermediates by CCT/TriC 25
- G beta:gamma signalling through PI3Kgamma 25
- G protein gated Potassium channels 25
- Gap-filling DNA repair synthesis and ligation in GG-NER 25
- Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 25
- Interleukin-7 signaling 25
- NOTCH3 Activation and Transmission of Signal to the Nucleus 25
- NOTCH3 Intracellular Domain Regulates Transcription 25
- Nuclear Events (kinase and transcription factor activation) 25
- Regulation of IFNA signaling 25
- Resolution of AP sites via the multiple-nucleotide patch replacement pathway 25
- Signaling by EGFR in Cancer 25
- Signaling by Erythropoietin 25
- Signaling by NTRK2 (TRKB) 25
- TRP channels 25
- Assembly and cell surface presentation of NMDA receptors 24
- Cytosolic sulfonation of small molecules 24
- Cytosolic tRNA aminoacylation 24
- DARPP-32 events 24
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling 24
- Glucuronidation 24
- Glutamate Neurotransmitter Release Cycle 24
- Growth hormone receptor signaling 24
- Interleukin-6 family signaling 24
- MicroRNA (miRNA) biogenesis 24
- Miscellaneous transport and binding events 24
- RHO GTPases Activate NADPH Oxidases 24
- RUNX2 regulates osteoblast differentiation 24
- Sema4D in semaphorin signaling 24
- Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 24
- Synthesis of very long-chain fatty acyl-CoAs 24
- TRAF6 mediated NF-kB activation 24
- Telomere C-strand (Lagging Strand) Synthesis 24
- Triglyceride catabolism 24
- Xenobiotics 24
- APC/C:Cdc20 mediated degradation of Cyclin B 23
- Abortive elongation of HIV-1 transcript in the absence of Tat 23
- BBSome-mediated cargo-targeting to cilium 23
- Dopamine Neurotransmitter Release Cycle 23
- Downregulation of SMAD2/3:SMAD4 transcriptional activity 23
- FRS-mediated FGFR1 signaling 23
- HDMs demethylate histones 23
- Incretin synthesis, secretion, and inactivation 23
- Initial triggering of complement 23
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 23
- Laminin interactions 23
- Long-term potentiation 23
- Nucleotide salvage 23
- PI-3K cascade:FGFR2 23
- RAF-independent MAPK1/3 activation 23
- RNA Polymerase III Transcription Termination 23
- SHC-mediated cascade:FGFR2 23
- Termination of O-glycan biosynthesis 23
- The canonical retinoid cycle in rods (twilight vision) 23
- Thromboxane signalling through TP receptor 23
- ADP signalling through P2Y purinoceptor 12 22
- Acyl chain remodelling of PS 22
- Blood group systems biosynthesis 22
- CD28 dependent PI3K/Akt signaling 22
- Citric acid cycle (TCA cycle) 22
- Common Pathway of Fibrin Clot Formation 22
- Deadenylation of mRNA 22
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 22
- E2F mediated regulation of DNA replication 22
- ERK/MAPK targets 22
- FRS-mediated FGFR4 signaling 22
- IKK complex recruitment mediated by RIP1 22
- Intrinsic Pathway of Fibrin Clot Formation 22
- Mitochondrial calcium ion transport 22
- NOTCH2 Activation and Transmission of Signal to the Nucleus 22
- Neurodegenerative Diseases 22
- Post-chaperonin tubulin folding pathway 22
- Prostacyclin signalling through prostacyclin receptor 22
- RA biosynthesis pathway 22
- SHC1 events in ERBB2 signaling 22
- Signaling by FGFR3 in disease 22
- Signaling by FGFR3 point mutants in cancer 22
- mTORC1-mediated signalling 22
- rRNA processing in the mitochondrion 22
- CD209 (DC-SIGN) signaling 21
- CTLA4 inhibitory signaling 21
- Cellular hexose transport 21
- ER Quality Control Compartment (ERQC) 21
- Interleukin-37 signaling 21
- Mitochondrial tRNA aminoacylation 21
- Negative regulation of MET activity 21
- Negative regulation of NMDA receptor-mediated neuronal transmission 21
- Nephrin family interactions 21
- PCNA-Dependent Long Patch Base Excision Repair 21
- PI-3K cascade:FGFR1 21
- Pink/Parkin Mediated Mitophagy 21
- Presynaptic function of Kainate receptors 21
- RHO GTPases activate PAKs 21
- Regulation of FZD by ubiquitination 21
- Regulation of gene expression in beta cells 21
- SHC-mediated cascade:FGFR1 21
- SUMOylation of transcription factors 21
- Signal transduction by L1 21
- Synaptic adhesion-like molecules 21
- Synthesis of Leukotrienes (LT) and Eoxins (EX) 21
- TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 21
- Unblocking of NMDA receptors, glutamate binding and activation 21
- VxPx cargo-targeting to cilium 21
- ZBP1(DAI) mediated induction of type I IFNs 21
- Chondroitin sulfate biosynthesis 20
- Class I peroxisomal membrane protein import 20
- Defective B3GALT6 causes EDSP2 and SEMDJL1 20
- Defective B3GAT3 causes JDSSDHD 20
- Defective B4GALT7 causes EDS, progeroid type 20
- Defects in vitamin and cofactor metabolism 20
- Digestion 20
- FGFR2 ligand binding and activation 20
- FRS-mediated FGFR3 signaling 20
- G beta:gamma signalling through CDC42 20
- G beta:gamma signalling through PLC beta 20
- HS-GAG degradation 20
- Inactivation of APC/C via direct inhibition of the APC/C complex 20
- Inflammasomes 20
- Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20
- Lagging Strand Synthesis 20
- Listeria monocytogenes entry into host cells 20
- NOTCH4 Intracellular Domain Regulates Transcription 20
- Nitric oxide stimulates guanylate cyclase 20
- PI-3K cascade:FGFR4 20
- PKA activation in glucagon signalling 20
- Ras activation upon Ca2+ influx through NMDA receptor 20
- Receptor-type tyrosine-protein phosphatases 20
- SHC-mediated cascade:FGFR4 20
- Sema4D induced cell migration and growth-cone collapse 20
- Signaling by Hippo 20
- Signaling by NODAL 20
- Signalling to RAS 20
- Syndecan interactions 20
- Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 20
- TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20
- Assembly of active LPL and LIPC lipase complexes 19
- Biosynthesis of specialized proresolving mediators (SPMs) 19
- Branched-chain amino acid catabolism 19
- Cobalamin (Cbl, vitamin B12) transport and metabolism 19
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19
- Ephrin signaling 19
- GABA synthesis, release, reuptake and degradation 19
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dto class
- protein 8488
- Enzyme 2293
- Transporter 855
- Nucleic acid binding 735
- Transcription factor 686
- Enzyme modulator 663
- Kinase 626
- G-protein coupled receptor 608
- Protease 567
- Class A rhodopsin like 524
- Protein kinase 508
- Transferase 451
- Hydrolase 441
- Signaling 415
- SLC superfamily of solute carriers 413
- Cellular structure 408
- RNA binding protein 408
- Oxidoreductase 360
- Ion channel 350
- Receptor 300
- Olfactory receptor 213
- DNA binding protein 210
- Zinc finger transcription factor 195
- Ligase 189
- Serine protease 185
- Actin family cytoskeletal protein 179
- G-protein modulator 179
- Cysteine protease 175
- Metalloprotease 173
- C2H2 zinc finger transcription factor 166
- Helix-turn-helix transcription factor 165
- Protease inhibitor 164
- Phosphatase 153
- Microtubule family cytoskeletal protein 149
- KRAB box transcription factor 141
- Ribosomal protein 141
- Dehydrogenase 140
- G-protein 122
- mRNA processing factor 114
- Glycosyltransferase 112
- Growth factor 109
- Calcium-binding protein 108
- Nuclease 102
- Kinase modulator 98
- Cytokine receptor 93
- TK group 93
- Homeodomain transcription factor 92
- Epigenetic regulator 89
- Ubiquitin-protein ligase 88
- Nucleotidyltransferase 87
- mRNA splicing factor 87
- Calmodulin 81
- Intracellular calcium-sensing protein 81
- Other group 80
- Small GTPase 79
- Non-motor actin binding protein 76
- CAMK group 75
- Isomerase 74
- Transcription cofactor 72
- Winged helix/forkhead transcription factor 71
- Lipase 69
- Oxygenase 67
- CMGC group 66
- Chromatin/chromatin-binding protein 64
- Extracellular structure 64
- Membrane trafficking regulatory protein 64
- Cell adhesion 63
- Oxidase 63
- Polymerase 63
- Helicase 62
- Non-protein kinase 62
- AGC group 61
- Cell-cell junction 61
- Chaperone 60
- Serine protease inhibitor 60
- Guanyl-nucleotide exchange factor 58
- Basic helix-loop-helix transcription factor 57
- Immunoglobulin receptor superfamily 57
- Protein phosphatase 56
- Unclassified protein 56
- Non-motor microtubule binding protein 53
- Acetyltransferase 52
- Potassium channel family 52
- SLC25 family of mitochondrial transporters 52
- Acyltransferase 51
- Histone 50
- Chemokine 48
- Nuclear receptor 48
- Cytokine 47
- Lyase 47
- Microtubule binding motor protein 46
- Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family 46
- STE group 46
- Hormone 45
- Kinase activator 45
- Translation factor 45
- Immune response 44
- Phospholipase 43
- TKL group 43
- ATP-binding cassette transporter family 42
- Methyltransferase 41
- Extracellular matrix glycoprotein 40
- DNA-directed RNA polymerase 39
- Reductase 39
- Vesicle coat protein 39
- Heterotrimeric G-protein 38
- Phosphatase modulator 38
- P-type ATPases 36
- RNA helicase 36
- Tight junction 36
- F-type and V-type ATPases 35
- Membrane-bound signaling molecule 34
- Reader 34
- Immunoglobulin fold transcription factor 33
- Adhesion class 32
- Translation initiation factor 32
- Basic leucine zipper transcription factor 30
- SNARE protein 30
- Actin and actin related protein 29
- Eraser 29
- Lipid kinase 29
- STE20 family 29
- Deaminase 28
- Epimerase/racemase 28
- Actin binding motor protein 27
- Rel homology transcription factor 27
- SLC35 family of nucleotide sugar transporters 27
- Writer 26
- Protein methyltransferase 25
- Atypical group 24
- DNA helicase 24
- Nucleotide phosphatase 24
- Peroxidase 24
- Ribonucleoprotein 24
- Taste 2 receptor 24
- Aminoacyl-tRNA synthetase 23
- Aspartic protease 23
- Chemokine receptor 23
- Esterase 23
- SLC22 family of organic cation and anion transporters 23
- Transient receptor potential calcium channel (TRP-CC) family 23
- V-type ATPase 23
- CAMKL family 22
- Class C metabotropic glutamate/pheromone 22
- DNA-directed DNA polymerase 22
- CDK family 21
- Gap junction 21
- Phosphatase inhibitor 21
- Tubulin 20
- Type I cytokine receptor 20
- Gamma-aminobutyric acid receptor subfamily 19
- Major histocompatibility complex antigen 19
- SLC6 neurotransmitter transporter family 19
- Glutamate-gated ion channel (GIC) Family of Neurotransmitter Receptors 18
- Histone deacetylase 18
- Purinoceptor 18
- Exoribonuclease 17
- Mitochondrial nucleotide transporter subfamily 17
- Acetylcholine receptor subfamily 16
- Inward rectifier-type potassium channel family 16
- Class B secretin like 15
- Glycosidase 15
- Kinase inhibitor 15
- Mitochondrial amino acid transporter subfamily 15
- SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 15
- Transaminase 15
- Two pore domain potassium channel family 15
- Bromodomain 14
- Eph family 14
- Intermediate filament 14
- Intermediate filament binding protein 14
- MAPK family 14
- Methyl-lysine/arginine binding protein 14
- Other small molecule kinase 14
- Phospholipid-transporting ATPases 14
- SLC16 family of monocarboxylate transporters 14
- SLC2 family of hexose and sugar alcohol transporters 14
- SLC39 family of metal ion transporters 14
- mRNA polyadenylation factor 14
- Apolipoprotein 13
- Decarboxylase 13
- HMG box transcription factor 13
- Neuropeptide 13
- SLC7 family 13
- SLC9 family of sodium/hydrogen exchangers 13
- SRC family 13
- 5-hydroxytryptamine receptor 12
- ABCA subfamily 12
- Aquaporin 12
- C-C chemokine receptor 12
- CK1 group 12
- Calcium channel alpha-1 subunit family 12
- Chaperonin 12
- Extracellular matrix structural protein 12
- F-type ATPase 12
- Other ion channel 12
- SLC5 family of sodium-dependent glucose transporters 12
- STKR family 12
- Type II cytokine receptor 12
- ABCB subfamily 11
- ABCC subfamily 11
- Class F frizzled-type 11
- Damaged DNA-binding protein 11
- Endoribonuclease 11
- Lysine demethylase 11
- NEK family 11
- SLC38 family of sodium-dependent neutral amino acid transporters 11
- SLCO family of organic anion transporting polypeptides 11
- Cyclic nucleotide-gated cation channel family 10
- DYRK family 10
- Frizzled receptor 10
- MLK family 10
- Mas proto-oncogene and Mas-related (MRGs) receptor 10
- P2Y receptor 10
- PI3/PI4 kinase family 10
- Phosphorylase 10
- SLC30 zinc transporter family 10
- SLC4 family of bicarbonate transporters 10
- Sodium channel family 10
- Tumor necrosis factor family member 10
- Adrenoceptor 9
- Amiloride-sensitive sodium channel family 9
- Ca2+-ATPases 9
- Chloride channel family 9
- Orphan or poorly characterized SLC22 family members 9
- PKC family 9
- SET domain 9
- SLC12 family of cation-coupled chloride transporters 9
- SLC17 phosphate and organic anion transporter family 9
- SLC26 family of anion exchangers 9
- A (Shaker) subfamily 8
- Calcium channel auxiliary subunit 1-8 (cca) family 8
- Calcium-activated subfamily 8
- Class II transporters 8
- Endodeoxyribonuclease 8
- H (Eag) subfamily 8
- Jumonji domain-containing 8
- Metabotropic glutamate receptor 8
- Na+/K+-ATPases 8
- Neurotrophic factor 8
- RSK family 8
- Replication origin binding protein 8
- STE11 family 8
- ATP-gated p2x receptor cation channel (p2x receptor) family 7
- CK1 family 7
- Cadherin 7
- Carbohydrate kinase 7
- Chromodomain 7
- DMPK family 7
- GRK family 7
- HDAC class III 7
- LTrpC subfamily 7
- Miscellaneous SLC25 mitochondrial transporters 7
- Nucleoside kinase 7
- Phosphodiesterase 7
- Protein arginine methyltransferase 7
- SLC1 family of amino acid transporters 7
- SLC10 family of sodium-bile acid co-transporters 7
- SLC28 and SLC29 families of nucleoside transporters 7
- STE7 family 7
- STKR Type 1 subfamily 7
- Storage 7
- Alpha adrenoceptor 6
- Dopamine receptor 6
- GABA transporter subfamily 6
- Glucagon receptor 6
- Glucosidase 6
- Intracellular chloride channel (clic) family 6
- Lysophospholipid (LPA) receptor 6
- Melanin-concentrating hormone receptor 6
- Mitochondrial di- and tri-carboxylic acid transporter subfamily 6
- Mitochondrial uncoupling proteins 6
- Neutral amino acid transporter subfamily 6
- Organic anion transporters (OATs) 6
- Orphan SLC38 transporters 6
- Polycystin cation channel (pcc) family 6
- Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family 6
- SLC24 family of sodium/potassium/calcium exchangers 6
- SLC27 family of fatty acid transporters 6
- SLC57 NiPA-like magnesium transporter family 6
- STrpC subfamily 6
- Sodium-dependent HCO3- transporters 6
- Transmembrane channel (TMC) family 6
- TrpV subfamily 6
- 5-HT1 receptor 5
- 5-HT3 receptor sub-subfamily 5
- 5-hydroxytryptamine receptor subfamily 5
- ABCG subfamily 5
- Acetylcholine receptor (muscarinic) 5
- Alpha family 5
- Antibacterial response protein 5
- CAMK1 family 5
- CDKL family 5
- Calcium-dependent chloride channel (ca-clc) family 5
- Class I transporters 5
- DAPK family 5
- DNA glycosylase 5
- Dehydratase 5
- ERK subfamily 5
- GRK subfamily 5
- Glutamate transporter subfamily 5
- Glycine receptor subfamily 5
- Glycosylase 5
- Hexose transporter family 5
- KQT subfamily 5
- Leukotriene receptor 5
- MADS box transcription factor 5
- MAPKAPK family 5
- MAST family 5
- MBT domain 5
- MLCK family 5
- Melanocortin receptor 5
- Mutase 5
- Nucleotide kinase 5
- PDGFR family 5
- PDHK family 5
- PIKK family 5
- PLK family 5
- RAF family 5
- RGC family 5
- RGC group 5
- RIPK family 5
- SLC13 family of sodium-dependent sulphate/carboxylate transporters 5
- SLC44 choline transporter-like family 5
- STKR Type 2 subfamily 5
- Surfactant 5
- TAIRE subfamily 5
- TEC family 5
- TSSK family 5
- ULK family 5
- 3-Ketosteroid receptors 4
- ABC1 family 4
- Adenosine receptor 4
- Angiotensin receptor 4
- Anion channel-forming bestrophin (bestrophin) family 4
- Anion exchangers 4
- C (Shaw) subfamily 4
- C-X-C chemokine receptor 4
- CAMK2 family 4
- CK2 family 4
- CLK family 4
- Calcium channel auxiliary subunit 2 types 1-4 (cca-2) family 4
- Calcium channel auxiliary subunit types 1-4 (cca-) family 4
- Calcium-activated potassium channel auxiliary subunit slowpoke- (slo) family 4
- Cation channel sperm-associated family 4
- Cyclase 4
- DNA topoisomerase 4
- EGFR family 4
- Exodeoxyribonuclease 4
- FGFR family 4
- Free fatty acid receptor 4
- Fxyd family 4
- G subfamily 4
- GEK subfamily 4
- Glycine transporter subfamily 4
- HDAC class I 4
- HDAC class IIa 4
- HIPK subfamily 4
- Histamine receptor 4
- Hsp90 family chaperone 4
- IKK family 4
- IRAK family 4
- Interleukin superfamily 4
- JAKA family 4
- KCNE subfamily 4
- KHS subfamily 4
- LISK family 4
- Latrophilin receptor 4
- MARK subfamily 4
- MLK subfamily 4
- NAK family 4
- NDR family 4
- Other 7TM proteins 4
- Other SLC26 anion exchangers 4
- P38 subfamily 4
- PEK family 4
- PKA family 4
- Plant homeodomain 4
- Proteinase-activated receptor 4
- Pyrophosphatase 4
- RSK subfamily 4
- SLC15 family of peptide transporters 4
- SLC18 family of vesicular amine transporters 4
- SLC29 family 4
- SLC36 family of proton-coupled amino acid transporters 4
- SLC37 family of phosphosugar/phosphate exchangers 4
- SLC45 family of putative sugar transporters 4
- SLC49 family of FLVCR-related heme transporters 4
- SLC56 Sideroflexins 4
- Sodium channel auxiliary subunit 1-4 (sca-) family 4
- Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters 4
- TRIO family 4
- Translation elongation factor 4
- Translation release factor 4
- Type I sodium-phosphate co-transporters 4
- WNK family 4
- 5-HT2 receptor 3
- ABCD subfamily of peroxisomal ABC transporters 3
- AKT family 3
- AUR family 3
- AXL family 3
- Adenylate kinase family 3
- Anaphylatoxin receptor 3
- Anion channel tweety (tweety) family 3
- Beta adrenoceptor 3
- Bombesin receptor 3
- CDK1 subfamily 3
- COUP-TF-like receptors 3
- Cadherin EGF LAG (CELSR) receptor 3
- Calcium homeostasis modulator calcium channel (calhm-c) family 3
- Carbohydrate phosphatase 3
- D (Shal) subfamily 3
- DCAMKL family 3
- DCK/DGK family 3
- Deacetylase 3
- Diacylglycerol kinase family 3
- Dyrk2 subfamily 3
- Endothelin receptor 3
- Epithelial chloride channel (e-clc) family 3
- Estrogen-related receptors 3
- Formyl peptide receptor 3
- GABA-B receptor 3
- Galactosidase 3
- Galanin receptor 3
- Gap junction-forming innexin (innexin) family 3
- Glycoprotein hormone receptor 3
- H+/K+-ATPases 3
- Hydroxycarboxylic acid receptor 3
- INSR family 3
- Immunoglobulin 3
- Immunoglobulin superfamily cell adhesion molecule 3
- Inositol phosphokinase (IPK) family 3
- JNK subfamily 3
- LMR family 3
- Liver X receptor-like receptors 3
- Lysine-specific demethylase 3
- MAPKAPK subfamily 3
- MSN subfamily 3
- Monoamine transporter subfamily 3
- Myelin protein 3
- Nerve growth factor IB-like receptors 3
- Neuropeptide Y receptor 3
- Organic cation transporters (OCT) 3
- Organic zwitterions/cation transporters (OCTN) 3
- Other-UNIQUE family 3
- P53-like transcription factor 3
- PAKA subfamily 3
- PIM family 3
- PKC alpha subfamily 3
- PKD family 3
- PKN family 3
- Peroxisome proliferator-activated receptors 3
- Polycystin subfamily 3
- QIK subfamily 3
- RCK family 3
- RIO family 3
- Retinoic acid receptors 3
- Retinoic acid-related orphans 3
- Retinoid X receptors 3
- Runt transcription factor 3
- S subfamily 3
- SCY1 family 3
- SGK family 3
- SLC19 family of vitamin transporters 3
- SLC23 family of ascorbic acid transporters 3
- SLC28 family 3
- SLC34 family of sodium phosphate co-transporters 3
- SLC41 family of divalent cation transporters 3
- SLC42 family of Rhesus glycoprotein ammonium transporters 3
- SLC43 family of large neutral amino acid transporters 3
- SLC46 family of folate transporters 3
- SLC52 family of riboflavin transporters 3
- SLC55 Mitochondrial cation/proton exchangers 3
- SLC63 Sphingosine-phosphate transporters 3
- SLC8 family of sodium/calcium exchangers 3
- SRPK family 3
- System A-like transporters 3
- TAO subfamily 3
- TATA-binding transcription factor 3
- TRBL family 3
- TRK family 3
- Tachykinin receptor 3
- Taste 1 receptor 3
- Type II pantothenate kinase family 3
- VEGFR family 3
- VRK family 3
- Vesicular glutamate transporters (VGLUTs) 3
- Vitamin D receptor-like receptors 3
- Voltage-gated potassium channel -subunit (kv) family 3
- Vomeronasal receptor 3
- WEE family 3
- YANK family 3
- YSK subfamily 3
- ABC1-A subfamily 2
- ABL family 2
- ACK family 2
- ALK family 2
- AMPK subfamily 2
- Alanine/serine/cysteine transporter subfamily 2
- Anion channels 2
- Annexin 2
- B (Shab) subfamily 2
- BARK subfamily 2
- BRSK subfamily 2
- BUB family 2
- Bile acid receptor 2
- Bradykinin receptor 2
- CAMK-UNIQUE family 2
- CAMKK family 2
- CDK4 subfamily 2
- CDK8 subfamily 2
- CSK family 2
- Calcitonin receptor 2
- Calcium-sensing receptor 2
- Cannabinoid receptor 2
- Chloride/bicarbonate exchangers 2
- Cholecystokinin receptor 2
- Choline/ethanolamine kinase family 2
- Cu+-ATPases 2
- Cysteine protease inhibitor 2
- DAX-like receptors 2
- DDR family 2
- DNA ligase 2
- DNA photolyase 2
- Dyrk1 subfamily 2
- Estrogen receptors 2
- FAK family 2
- FER family 2
- FRAY subfamily 2
- Fushi tarazu F1-like receptors 2
- GSK family 2
- GSK subfamily 2
- Golgi pH regulator family 2
- HDAC class IIb 2
- Hepatocyte nuclear factor-4 receptors 2
- Hexokinase family 2
- Hydroxylase 2
- IRE family 2
- KCNJ12 subfamily 2
- LIMK subfamily 2
- LRRK family 2
- Lambda repressor-like transcription factor 2
- MET family 2
- MNK subfamily 2
- MSK subfamily 2
- MST subfamily 2
- Mechanical nociceptor, piezo (piezo) family 2
- Melatonin receptor 2
- Meta subfamily 2
- Methyl-CpG-binding domain 2
- NKF1 family 2
- NKF3 family 2
- NKF4 family 2
- NRBP family 2
- Neuromedin U receptor 2
- Neuropeptide FF/neuropeptide AF receptor 2
- Neuropeptide W/neuropeptide B receptor 2
- Neurotensin receptor 2
- NinaC subfamily 2
- NuaK subfamily 2
- P70 subfamily 2
- PAKB subfamily 2
- PHK family 2
- PITSLRE subfamily 2
- PKC delta subfamily 2
- PKC eta subfamily 2
- PKC iota subfamily 2
- PKG family 2
- Parathyroid hormone receptor 2
- Phospholemman (plm) family 2
- Phosphorylase b kinase regulatory chain family 2
- Protein kinase receptor 2
- ROCK subfamily 2
- ROR family 2
- RSKL family 2
- Rev-Erb receptors 2
- SLC11 family of proton-coupled metal ion transporters 2
- SLC14 family of facilitative urea transporters 2
- SLC20 family of sodium-dependent phosphate transporters 2
- SLC26A/SulP transporter family 2
- SLC3 family 2
- SLC31 family of copper transporters 2
- SLC47 family of multidrug and toxin extrusion transporters 2
- SLC51 family of steroid-derived molecule transporters 2
- SLC54 Mitochondrial pyruvate carriers 2
- SLC58 MagT-like magnesium transporter family 2
- SLC59 Sodium-dependent lysophosphatidylcholine symporter family 2
- SLC60 Glucose transporters 2
- SLC65 NPC-type cholesterol transporters 2
- SLK subfamily 2
- STE-UNIQUE family 2
- SYK family 2
- Sodium myo-inositol cotransporter transporters 2
- System N-like transporters 2
- TIE family 2
- TLK family 2
- TTBK family 2
- Tailless-like receptors 2
- Testicular receptors 2
- Thyroid Hormone Receptors 2
- Tmem38 family 2
- Tudor domain 2
- Tumor necrosis factor receptor 2
- Two pore calcium channel subfamily 2
- Uridine kinase family 2
- V subfamily 2
- Voltage-gated proton channel (vpc) family 2
- 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1
- 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1
- 1,4-alpha-glucan-branching enzyme 1
- 1,5-anhydro-D-fructose reductase 1
- 1-aminocyclopropane-1-carboxylate synthase-like protein 1 1
- 1-phosphatidylinositol 3-phosphate 5-kinase 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 1
- 10 kDa heat shock protein, mitochondrial 1
- 11-cis retinol dehydrogenase 1
- 116 kDa U5 small nuclear ribonucleoprotein component 1
- 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor 1
- 14-3-3 protein beta/alpha 1
- 14-3-3 protein epsilon 1
- 14-3-3 protein eta 1
- 14-3-3 protein gamma 1
- 14-3-3 protein sigma 1
- 14-3-3 protein theta 1
- 14-3-3 protein zeta/delta 1
- 17-beta-hydroxysteroid dehydrogenase 14 1
- 17-beta-hydroxysteroid dehydrogenase type 6 1
- 2',3'-cyclic-nucleotide 3'-phosphodiesterase 1
- 2',5'-phosphodiesterase 12 1
- 2'-5'-oligoadenylate synthase 1 1
- 2'-5'-oligoadenylate synthase 2 1
- 2'-5'-oligoadenylate synthase 3 1
- 2'-5'-oligoadenylate synthase-like protein 1
- 2,4-dienoyl-CoA reductase, mitochondrial 1
- 2-5a-dependent ribonuclease 1
- 2-acylglycerol O-acyltransferase 1 1
- 2-acylglycerol O-acyltransferase 2 1
- 2-acylglycerol O-acyltransferase 3 1
- 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial 1
- 2-hydroxyacyl-CoA lyase 1 1
- 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 1
- 2-oxoglutarate receptor 1 1
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 1
- 2-phosphoxylose phosphatase 1 1
- 25-hydroxycholesterol 7-alpha-hydroxylase 1
- 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1
- 26S proteasome non-ATPase regulatory subunit 1 1
- 26S proteasome non-ATPase regulatory subunit 12 1
- 26S proteasome non-ATPase regulatory subunit 13 1
- 26S proteasome non-ATPase regulatory subunit 14 1
- 26S proteasome non-ATPase regulatory subunit 2 1
- 26S proteasome non-ATPase regulatory subunit 3 1
- 26S proteasome non-ATPase regulatory subunit 4 1
- 26S proteasome non-ATPase regulatory subunit 7 1
- 26S proteasome non-ATPase regulatory subunit 8 1
- 26S proteasome non-ATPase regulatory subunit 9 1
- 26S proteasome regulatory subunit 10B 1
- 26S proteasome regulatory subunit 4 1
- 26S proteasome regulatory subunit 6A 1
- 26S proteasome regulatory subunit 6B 1
- 26S proteasome regulatory subunit 7 1
- 26S proteasome regulatory subunit 8 1
- 28S ribosomal protein S11, mitochondrial 1
- 28S ribosomal protein S12, mitochondrial 1
- 28S ribosomal protein S14, mitochondrial 1
- 28S ribosomal protein S16, mitochondrial 1
- 28S ribosomal protein S18c, mitochondrial 1
- 28S ribosomal protein S2, mitochondrial 1
- 28S ribosomal protein S24, mitochondrial 1
- 28S ribosomal protein S27, mitochondrial 1
- 28S ribosomal protein S29, mitochondrial 1
- 28S ribosomal protein S35, mitochondrial 1
- 28S ribosomal protein S5, mitochondrial 1
- 28S ribosomal protein S7, mitochondrial 1
- 3 beta-hydroxysteroid dehydrogenase type 7 1
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 1
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 1
- 3'(2'),5'-bisphosphate nucleotidase 1 1
- 3'-5' exoribonuclease 1 1
- 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 1
- 3-hydroxyacyl-CoA dehydrogenase type-2 1
- 3-hydroxyisobutyrate dehydrogenase, mitochondrial 1
- 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 1
- 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic 1
- 3-ketoacyl-CoA thiolase, mitochondrial 1
- 3-ketoacyl-CoA thiolase, peroxisomal 1
- 3-mercaptopyruvate sulfurtransferase 1
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2 1
- 3-oxo-5-beta-steroid 4-dehydrogenase 1
- 3-phosphoinositide-dependent protein kinase 1 1
- 39S ribosomal protein L1, mitochondrial 1
- 39S ribosomal protein L11, mitochondrial 1
- 39S ribosomal protein L12, mitochondrial 1
- 39S ribosomal protein L13, mitochondrial 1
- 39S ribosomal protein L14, mitochondrial 1
- 39S ribosomal protein L16, mitochondrial 1
- 39S ribosomal protein L17, mitochondrial 1
- 39S ribosomal protein L18, mitochondrial 1
- 39S ribosomal protein L19, mitochondrial 1
- 39S ribosomal protein L20, mitochondrial 1
- 39S ribosomal protein L21, mitochondrial 1
- 39S ribosomal protein L22, mitochondrial 1
- 39S ribosomal protein L23, mitochondrial 1
- 39S ribosomal protein L24, mitochondrial 1
- 39S ribosomal protein L35, mitochondrial 1
- 39S ribosomal protein L38, mitochondrial 1
- 39S ribosomal protein L39, mitochondrial 1
- 39S ribosomal protein L41, mitochondrial 1
- 39S ribosomal protein L43, mitochondrial 1
- 39S ribosomal protein L44, mitochondrial 1
- 39S ribosomal protein L47, mitochondrial 1
- 39S ribosomal protein L48, mitochondrial 1
- 39S ribosomal protein L49, mitochondrial 1
- 39S ribosomal protein L51, mitochondrial 1
- 39S ribosomal protein S18a, mitochondrial 1
- 4-aminobutyrate aminotransferase, mitochondrial 1
- 4-hydroxy-2-oxoglutarate aldolase, mitochondrial 1
- 4-hydroxybenzoate polyprenyltransferase, mitochondrial 1
- 4-hydroxyphenylpyruvate dioxygenase 1
- 4-hydroxyphenylpyruvate dioxygenase-like protein 1
- 4-trimethylaminobutyraldehyde dehydrogenase 1
- 40S ribosomal protein S10 1
- 40S ribosomal protein S11 1
- 40S ribosomal protein S12 1
- 40S ribosomal protein S13 1
- 40S ribosomal protein S14 1
- 40S ribosomal protein S15 1
- 40S ribosomal protein S15a 1
- 40S ribosomal protein S17 1
- 40S ribosomal protein S18 1
- 40S ribosomal protein S19 1
- 40S ribosomal protein S2 1
- 40S ribosomal protein S20 1
- 40S ribosomal protein S21 1
- 40S ribosomal protein S23 1
- 40S ribosomal protein S24 1
- 40S ribosomal protein S26 1
- 40S ribosomal protein S27 1
- 40S ribosomal protein S27-like 1
- 40S ribosomal protein S28 1
- 40S ribosomal protein S3 1
- 40S ribosomal protein S3a 1
- 40S ribosomal protein S4, X isoform 1
- 40S ribosomal protein S5 1
- 40S ribosomal protein S6 1
- 40S ribosomal protein S7 1
- 40S ribosomal protein S8 1
- 40S ribosomal protein S9 1
- 40S ribosomal protein SA 1
- 45 kDa calcium-binding protein 1
- 4F2 cell-surface antigen heavy chain 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-1 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 1
- 5'-AMP-activated protein kinase subunit beta-1 1
- 5'-AMP-activated protein kinase subunit beta-2 1
- 5'-AMP-activated protein kinase subunit gamma-1 1
- 5'-AMP-activated protein kinase subunit gamma-2 1
- 5'-AMP-activated protein kinase subunit gamma-3 1
- 5'-nucleotidase 1
- 5'-nucleotidase domain-containing protein 1 1
- 5'-nucleotidase domain-containing protein 2 1
- 5'-nucleotidase domain-containing protein 3 1
- 5,6-dihydroxyindole-2-carboxylic acid oxidase 1
- 5-HT4 receptor 1
- 5-HT5 receptor 1
- 5-HT6 receptor 1
- 5-HT7 receptor 1
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial 1
- 5-aminolevulinate synthase, nonspecific, mitochondrial 1
- 5-formyltetrahydrofolate cyclo-ligase 1
- 5-hydroxytryptamine receptor 1D 1
- 5-hydroxytryptamine receptor 1E 1
- 5-hydroxytryptamine receptor 1a 1
- 5-hydroxytryptamine receptor 1b 1
- 5-hydroxytryptamine receptor 1f 1
- 5-hydroxytryptamine receptor 2A 1
- 5-hydroxytryptamine receptor 2B 1
- 5-hydroxytryptamine receptor 2c 1
- 5-hydroxytryptamine receptor 3A 1
- 5-hydroxytryptamine receptor 3B 1
- 5-hydroxytryptamine receptor 3C 1
- 5-hydroxytryptamine receptor 3d 1
- 5-hydroxytryptamine receptor 3e 1
- 5-hydroxytryptamine receptor 4 1
- 5-hydroxytryptamine receptor 5a 1
- 5-hydroxytryptamine receptor 6 1
- 5-hydroxytryptamine receptor 7 1
- 5-methylcytosine rRNA methyltransferase NSUN4 1
- 5-oxoprolinase 1
- 55 kDa erythrocyte membrane protein 1
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 1
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 1
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 1
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 1
- 6-phosphogluconate dehydrogenase, decarboxylating 1
- 6-phosphogluconolactonase 1
- 60 kDa SS-A/Ro ribonucleoprotein 1
- 60S ribosomal protein L10 1
- 60S ribosomal protein L10-like 1
- 60S ribosomal protein L10a 1
- 60S ribosomal protein L11 1
- 60S ribosomal protein L12 1
- 60S ribosomal protein L13 1
- 60S ribosomal protein L13a 1
- 60S ribosomal protein L14 1
- 60S ribosomal protein L15 1
- 60S ribosomal protein L18 1
- 60S ribosomal protein L19 1
- 60S ribosomal protein L21 1
- 60S ribosomal protein L22 1
- 60S ribosomal protein L22-like 1 1
- 60S ribosomal protein L23 1
- 60S ribosomal protein L23a 1
- 60S ribosomal protein L24 1
- 60S ribosomal protein L26 1
- 60S ribosomal protein L26-like 1 1
- 60S ribosomal protein L27 1
- 60S ribosomal protein L27a 1
- 60S ribosomal protein L28 1
- 60S ribosomal protein L29 1
- 60S ribosomal protein L3 1
- 60S ribosomal protein L3-like 1
- 60S ribosomal protein L30 1
- 60S ribosomal protein L31 1
- 60S ribosomal protein L32 1
- 60S ribosomal protein L35 1
- 60S ribosomal protein L35a 1
- 60S ribosomal protein L36 1
- 60S ribosomal protein L36a 1
- 60S ribosomal protein L36a-like 1
- 60S ribosomal protein L37 1
- 60S ribosomal protein L38 1
- 60S ribosomal protein L39 1
- 60S ribosomal protein L39-like 1
- 60S ribosomal protein L5 1
- 60S ribosomal protein L6 1
- 60S ribosomal protein L7 1
- 60S ribosomal protein L7-like 1 1
- 60S ribosomal protein L7a 1
- 60S ribosomal protein L8 1
- 60S ribosomal protein L9 1
- 7,8-dihydro-8-oxoguanine triphosphatase 1
- 7-dehydrocholesterol reductase 1
- 7-methylguanosine phosphate-specific 5'-nucleotidase 1
- 72 kDa type IV collagenase 1
- 85/88 kDa calcium-independent phospholipase A2 1
- A disintegrin and metalloproteinase with thrombospondin motifs 1 1
- A disintegrin and metalloproteinase with thrombospondin motifs 10 1
- A disintegrin and metalloproteinase with thrombospondin motifs 12 1
- A disintegrin and metalloproteinase with thrombospondin motifs 13 1
- A disintegrin and metalloproteinase with thrombospondin motifs 14 1
- A disintegrin and metalloproteinase with thrombospondin motifs 15 1
- A disintegrin and metalloproteinase with thrombospondin motifs 16 1
- A disintegrin and metalloproteinase with thrombospondin motifs 17 1
- A disintegrin and metalloproteinase with thrombospondin motifs 18 1
- A disintegrin and metalloproteinase with thrombospondin motifs 19 1
- A disintegrin and metalloproteinase with thrombospondin motifs 2 1
- A disintegrin and metalloproteinase with thrombospondin motifs 20 1
- A disintegrin and metalloproteinase with thrombospondin motifs 3 1
- A disintegrin and metalloproteinase with thrombospondin motifs 4 1
- A disintegrin and metalloproteinase with thrombospondin motifs 5 1
- A disintegrin and metalloproteinase with thrombospondin motifs 6 1
- A disintegrin and metalloproteinase with thrombospondin motifs 7 1
- A disintegrin and metalloproteinase with thrombospondin motifs 8 1
- A disintegrin and metalloproteinase with thrombospondin motifs 9 1
- A-kinase anchor protein 1, mitochondrial 1
- ABC1-B subfamily 1
- ABC1-C subfamily 1
- ABCC family 1
- ABI gene family member 3 1
- ADAM DEC1 1
- ADAMTS-like protein 1 1
- ADAMTS-like protein 2 1
- ADAMTS-like protein 3 1
- ADAMTS-like protein 4 1
- ADAMTS-like protein 5 1
- ADM 1
- ADM2 1
- ADP-dependent glucokinase 1
- ADP-ribose pyrophosphatase, mitochondrial 1
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 1
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 1
- ADP-sugar pyrophosphatase 1
- ADP/ATP translocase 1 1
- ADP/ATP translocase 2 1
- ADP/ATP translocase 3 1
- ADP/ATP translocase 4 1
- AF4/FMR2 family member 1 1
- AF4/FMR2 family member 2 1
- AF4/FMR2 family member 3 1
- AF4/FMR2 family member 4 1
- AFG3-like protein 2 1
- AH receptor-interacting protein 1
- AK1 subfamily 1
- AK2 subfamily 1
- AK3 subfamily 1
- AMP deaminase 1 1
- AMP deaminase 2 1
- AMP deaminase 3 1
- AMSH-like protease 1
- AN1-type zinc finger protein 1 1
- AN1-type zinc finger protein 2A 1
- AN1-type zinc finger protein 2B 1
- AN1-type zinc finger protein 5 1
- AN1-type zinc finger protein 6 1
- AP-1 complex subunit beta-1 1
- AP-1 complex subunit gamma-1 1
- AP-1 complex subunit gamma-like 2 1
- AP-1 complex subunit mu-1 1
- AP-1 complex subunit mu-2 1
- AP-1 complex subunit sigma-1A 1
- AP-1 complex subunit sigma-2 1
- AP-1 complex subunit sigma-3 1
- AP-2 complex subunit alpha-1 1
- AP-2 complex subunit alpha-2 1
- AP-2 complex subunit beta 1
- AP-2 complex subunit mu 1
- AP-2 complex subunit sigma 1
- AP-3 complex subunit beta-1 1
- AP-3 complex subunit beta-2 1
- AP-3 complex subunit delta-1 1
- AP-3 complex subunit mu-1 1
- AP-3 complex subunit mu-2 1
- AP-3 complex subunit sigma-1 1
- AP-3 complex subunit sigma-2 1
- AP-4 complex subunit beta-1 1
- AP-4 complex subunit epsilon-1 1
- AP-4 complex subunit mu-1 1
- AP-4 complex subunit sigma-1 1
- AT-rich interactive domain-containing protein 3A 1
- AT-rich interactive domain-containing protein 3B 1
- AT-rich interactive domain-containing protein 3C 1
- AT-rich interactive domain-containing protein 4A 1
- AT-rich interactive domain-containing protein 4B 1
- AT-rich interactive domain-containing protein 5A 1
- AT-rich interactive domain-containing protein 5B 1
- ATP synthase F(0) complex subunit B1, mitochondrial 1
- ATP synthase mitochondrial F1 complex assembly factor 1 1
- ATP synthase protein 8 1
- ATP synthase subunit a 1
- ATP synthase subunit alpha, mitochondrial 1
- ATP synthase subunit beta, mitochondrial 1
- ATP synthase subunit d, mitochondrial 1
- ATP synthase subunit delta, mitochondrial 1
- ATP synthase subunit e, mitochondrial 1
- ATP synthase subunit epsilon, mitochondrial 1
- ATP synthase subunit f, mitochondrial 1
- ATP synthase subunit gamma, mitochondrial 1
- ATP synthase-coupling factor 6, mitochondrial 1
- ATP-binding cassette sub-family A member 1 1
- ATP-binding cassette sub-family A member 10 1
- ATP-binding cassette sub-family A member 12 1
- ATP-binding cassette sub-family A member 13 1
- ATP-binding cassette sub-family A member 2 1
- ATP-binding cassette sub-family A member 3 1
- ATP-binding cassette sub-family A member 5 1
- ATP-binding cassette sub-family A member 6 1
- ATP-binding cassette sub-family A member 7 1
- ATP-binding cassette sub-family A member 8 1
- ATP-binding cassette sub-family A member 9 1
- ATP-binding cassette sub-family B member 10, mitochondrial 1
- ATP-binding cassette sub-family B member 5 1
- ATP-binding cassette sub-family B member 6, mitochondrial 1
- ATP-binding cassette sub-family B member 7, mitochondrial 1
- ATP-binding cassette sub-family B member 8, mitochondrial 1
- ATP-binding cassette sub-family B member 9 1
- ATP-binding cassette sub-family C member 11 1
- ATP-binding cassette sub-family C member 8 1
- ATP-binding cassette sub-family C member 9 1
- ATP-binding cassette sub-family D member 1 1
- ATP-binding cassette sub-family D member 2 1
- ATP-binding cassette sub-family D member 3 1
- ATP-binding cassette sub-family D member 4 1
- ATP-binding cassette sub-family F member 1 1
- ATP-binding cassette sub-family F member 2 1
- ATP-binding cassette sub-family F member 3 1
- ATP-binding cassette sub-family G member 1 1
- ATP-binding cassette sub-family G member 2 1
- ATP-binding cassette sub-family G member 4 1
- ATP-binding cassette sub-family G member 5 1
- ATP-binding cassette sub-family G member 8 1
- ATP-citrate synthase 1
- ATP-dependent 6-phosphofructokinase, muscle type 1
- ATP-dependent 6-phosphofructokinase, platelet type 1
- ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial 1
- ATP-dependent DNA helicase DDX11 1
- ATP-dependent DNA helicase Q1 1
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Target Development Level
Panther Classes
- nucleic acid binding 1448
- transcription factor 916
- hydrolase 851
- transferase 817
- enzyme modulator 807
- receptor 768
- signaling molecule 617
- RNA binding protein 604
- transporter 602
- cytoskeletal protein 461
- DNA binding protein 435
- oxidoreductase 397
- kinase 352
- protease inhibitor 273
- G-protein modulator 264
- protease 256
- membrane traffic protein 251
- protein kinase 246
- G-protein coupled receptor 244
- zinc finger transcription factor 242
- serine protease 226
- ligase 220
- calcium-binding protein 218
- actin family cytoskeletal protein 212
- defense/immunity protein 204
- non-receptor serine/threonine protein kinase 194
- cysteine protease 193
- ion channel 188
- microtubule family cytoskeletal protein 185
- transfer/carrier protein 185
- cell adhesion molecule 184
- extracellular matrix protein 182
- metalloprotease 180
- dehydrogenase 172
- phosphatase 161
- cation transporter 160
- transcription cofactor 155
- G-protein 152
- calmodulin 148
- intracellular calcium-sensing protein 148
- ribosomal protein 147
- mRNA processing factor 145
- KRAB box transcription factor 142
- nuclease 131
- kinase modulator 124
- glycosyltransferase 122
- cytokine receptor 119
- growth factor 115
- chromatin/chromatin-binding protein 109
- cytokine 107
- mRNA splicing factor 105
- reductase 105
- homeodomain transcription factor 102
- cell junction protein 96
- chaperone 94
- ubiquitin-protein ligase 94
- oxidase 92
- lyase 91
- membrane-bound signaling molecule 90
- non-motor actin binding protein 89
- serine protease inhibitor 86
- helix-turn-helix transcription factor 85
- acyltransferase 82
- annexin 82
- extracellular matrix glycoprotein 80
- membrane trafficking regulatory protein 80
- small GTPase 79
- isomerase 76
- basic helix-loop-helix transcription factor 75
- guanyl-nucleotide exchange factor 74
- structural protein 73
- winged helix/forkhead transcription factor 73
- immunoglobulin receptor superfamily 71
- translation factor 71
- lipase 69
- acetyltransferase 67
- ligand-gated ion channel 67
- oxygenase 67
- helicase 64
- methyltransferase 64
- microtubule binding motor protein 61
- peptide hormone 61
- non-motor microtubule binding protein 59
- transmembrane receptor regulatory/adaptor protein 58
- protein phosphatase 57
- translation initiation factor 54
- kinase activator 52
- histone 50
- nucleotidyltransferase 50
- chemokine 48
- GABA receptor 47
- acetylcholine receptor 47
- voltage-gated ion channel 45
- nucleotide kinase 44
- C4 zinc finger nuclear receptor 43
- heterotrimeric G-protein 43
- phospholipase 43
- ribonucleoprotein 42
- DNA-directed RNA polymerase 39
- vesicle coat protein 39
- esterase 38
- phosphatase modulator 38
- amino acid transporter 37
- non-receptor tyrosine protein kinase 37
- RNA helicase 36
- tight junction 36
- ATP synthase 35
- DNA helicase 35
- ATP-binding cassette (ABC) transporter 34
- deaminase 33
- type I cytokine receptor 32
- SNARE protein 30
- basic leucine zipper transcription factor 30
- kinase inhibitor 30
- actin and actin related protein 29
- epimerase/racemase 28
- extracellular matrix structural protein 28
- Rel homology transcription factor 27
- actin binding motor protein 27
- antibacterial response protein 27
- nucleotide phosphatase 26
- C2H2 zinc finger transcription factor 25
- extracellular matrix linker protein 25
- peroxidase 24
- translation elongation factor 24
- aminoacyl-tRNA synthetase 23
- aspartic protease 23
- carbohydrate kinase 23
- endoribonuclease 23
- glycosidase 23
- DNA-directed DNA polymerase 22
- protein kinase receptor 22
- sodium channel 22
- voltage-gated sodium channel 22
- calcium channel 21
- dehydratase 21
- exoribonuclease 21
- gap junction 21
- phosphatase inhibitor 21
- pyrophosphatase 21
- voltage-gated calcium channel 21
- carbohydrate transporter 20
- damaged DNA-binding protein 20
- tubulin 20
- anion channel 19
- major histocompatibility complex antigen 19
- HMG box transcription factor 17
- mRNA polyadenylation factor 17
- transaminase 17
- mitochondrial carrier protein 16
- serine/threonine protein kinase receptor 16
- storage protein 16
- deacetylase 15
- decarboxylase 15
- immunoglobulin superfamily cell adhesion molecule 15
- endodeoxyribonuclease 14
- intermediate filament 14
- intermediate filament binding protein 14
- myelin protein 14
- apolipoprotein 13
- hydratase 13
- neuropeptide 13
- DNA methyltransferase 12
- TGF-beta receptor 12
- chaperonin 12
- potassium channel 12
- type II cytokine receptor 12
- voltage-gated potassium channel 12
- cadherin 10
- phosphodiesterase 10
- phosphorylase 10
- tumor necrosis factor family member 10
- RNA methyltransferase 9
- cyclase 9
- P53-like transcription factor 8
- complement component 8
- neurotrophic factor 8
- replication origin binding protein 8
- surfactant 8
- exodeoxyribonuclease 7
- translation release factor 7
- carbohydrate phosphatase 6
- glucosidase 6
- hydroxylase 6
- DNA glycosylase 5
- MADS box transcription factor 5
- adenylate cyclase 5
- amino acid kinase 5
- guanylate cyclase 5
- ionotropic glutamate receptor 5
- mutase 5
- DNA topoisomerase 4
- Hsp90 family chaperone 4
- interleukin superfamily 4
- transketolase 4
- tyrosine protein kinase receptor 4
- viral protein 4
- CREB-related transcription factor 3
- Runt transcription factor 3
- TATA-binding transcription factor 3
- galactosidase 3
- immunoglobulin 3
- DNA ligase 2
- DNA photolyase 2
- Lambda repressor-like transcription factor 2
- amylase 2
- cysteine protease inhibitor 2
- tumor necrosis factor receptor 2
- DNA polymerase processivity factor 1
- aldolase 1
- centromere DNA-binding protein 1
- phosphatase activator 1
- primase 1
- reverse transcriptase 1
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