TC-DAPK 6 - 10mM in DMSO, high purity , CAS No.315694-89-4(DMSO)

  • 10mM in DMSO
Item Number
T654587
Grouped product items
SKUSizeAvailabilityPrice Qty
T654587-1ml
1ml
Available within 8-12 weeks(?)
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$106.90
View related series
Apoptosis DAPK

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

TC-DAPK 6 is a potent, ATP-competitive, and highly selective DAPK inhibitor ( IC 50 =69 and 225 nM against DAPK1 and DAPK3 , respectively, with 10 μM ATP).

In Vitro

TC-DAPK 6 is found to be the most potent Death-associated protein kinase (DAPK) inhibitor with enzyme selectivity. When assayed with 10 μM ATP, the IC 50 values for DAPK1 and DAPK3 are 69 and 225 nM, respectively. TC-DAPK 6 also inhibits p70S6K (1 μM < IC 50 < 10 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 69 nM (DAPK1), 225 nM (DAPK3)

Names and Identifiers

Canonical SMILES C1=CC=C(C=C1)C=CC2=NC(=CC3=CN=CC=C3)C(=O)O2
Molecular Weight 276.29

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