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TC-I 2000 - ≥99%(HPLC), high purity , CAS No.1159996-20-9

  • ≥99%(HPLC)
Item Number
T287244
Grouped product items
SKUSizeAvailabilityPrice Qty
T287244-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
T287244-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$62.90
T287244-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
T287244-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$179.90
T287244-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90

TRPM8 blocker

View related series
TRPM Channel Blockers

Basic Description

SynonymsN-(4-Fluorophenyl)-3,4-dihydro-1-[4-(trifluoromethyl)phenyl]-2(1H)-isoquinolinecarboxamide;N-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide
Specifications & Purity≥99%(HPLC)
Biochemical and Physiological MechanismsTRPM8 channel blocker. Inhibitsicilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells (IC50= 53 nM).
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRPM8 Tclin Transient receptor potential cation channel subfamily M member 8 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-(4-fluorophenyl)-1-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamide
INCHI InChI=1S/C23H18F4N2O/c24-18-9-11-19(12-10-18)28-22(30)29-14-13-15-3-1-2-4-20(15)21(29)16-5-7-17(8-6-16)23(25,26)27/h1-12,21H,13-14H2,(H,28,30)
InChi Key ADCDUDFEGFKKQH-UHFFFAOYSA-N
Canonical SMILES C1CN(C(C2=CC=CC=C21)C3=CC=C(C=C3)C(F)(F)F)C(=O)NC4=CC=C(C=C4)F
Isomeric SMILES C1CN(C(C2=CC=CC=C21)C3=CC=C(C=C3)C(F)(F)F)C(=O)NC4=CC=C(C=C4)F
PubChem CID 57326210
Molecular Weight 414.4

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2408286Certificate of AnalysisMar 08, 2024 T287244
G2408287Certificate of AnalysisMar 08, 2024 T287244
G2408288Certificate of AnalysisMar 08, 2024 T287244
G2408289Certificate of AnalysisMar 08, 2024 T287244
G2408290Certificate of AnalysisMar 08, 2024 T287244
G2408291Certificate of AnalysisMar 08, 2024 T287244
G2408297Certificate of AnalysisMar 08, 2024 T287244
G2408298Certificate of AnalysisMar 08, 2024 T287244
G2408299Certificate of AnalysisMar 08, 2024 T287244
G2408301Certificate of AnalysisMar 08, 2024 T287244

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 41.44, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 8.29, Max Conc. mM: 20

Related Documents

Solution Calculators