Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T287244-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $39.90 | |
T287244-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $62.90 | |
T287244-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $109.90 | |
T287244-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $179.90 | |
T287244-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $279.90 |
TRPM8 blocker
Synonyms | N-(4-Fluorophenyl)-3,4-dihydro-1-[4-(trifluoromethyl)phenyl]-2(1H)-isoquinolinecarboxamide;N-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide |
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Specifications & Purity | ≥99%(HPLC) |
Biochemical and Physiological Mechanisms | TRPM8 channel blocker. Inhibitsicilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells (IC50= 53 nM). |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | N-(4-fluorophenyl)-1-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamide |
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INCHI | InChI=1S/C23H18F4N2O/c24-18-9-11-19(12-10-18)28-22(30)29-14-13-15-3-1-2-4-20(15)21(29)16-5-7-17(8-6-16)23(25,26)27/h1-12,21H,13-14H2,(H,28,30) |
InChi Key | ADCDUDFEGFKKQH-UHFFFAOYSA-N |
Canonical SMILES | C1CN(C(C2=CC=CC=C21)C3=CC=C(C=C3)C(F)(F)F)C(=O)NC4=CC=C(C=C4)F |
Isomeric SMILES | C1CN(C(C2=CC=CC=C21)C3=CC=C(C=C3)C(F)(F)F)C(=O)NC4=CC=C(C=C4)F |
PubChem CID | 57326210 |
Molecular Weight | 414.4 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2408286 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408287 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408288 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408289 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408290 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408291 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408297 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408298 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408299 | Certificate of Analysis | Mar 08, 2024 | T287244 |
G2408301 | Certificate of Analysis | Mar 08, 2024 | T287244 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 41.44, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 8.29, Max Conc. mM: 20 |
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