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TCN-213 , CAS No.T614356, Allosteric modulator of GluN2A

Item Number

T614356

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SKU	Size	Availability	Price	Qty
T614356-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
T614356-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

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Basic Description

Synonyms	TCN 213;TCN213
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of GluN2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	2-[[5-(benzylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(cyclohexylmethyl)acetamide
INCHI	InChI=1S/C18H24N4OS2/c23-16(19-11-14-7-3-1-4-8-14)13-24-18-22-21-17(25-18)20-12-15-9-5-2-6-10-15/h2,5-6,9-10,14H,1,3-4,7-8,11-13H2,(H,19,23)(H,20,21)
InChi Key	XBAZPYFIYYCZBO-UHFFFAOYSA-N
Canonical SMILES	C1CCC(CC1)CNC(=O)CSc1nnc(s1)NCc1ccccc1
Isomeric SMILES	C1CCC(CC1)CNC(=O)CSC2=NN=C(S2)NCC3=CC=CC=C3
PubChem CID	2608149

PubChem CID	2608149

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1. McKay S, Griffiths NH, Butters PA, Thubron EB, Hardingham GE, Wyllie DJ. (2012) Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist.. Br J Pharmacol, 166 (3): (924-37). [PMID:22022974]

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