| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| T487957-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $537.90 | |
| T487957-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,666.90 |
| Storage Temp | Store at -20°C |
|---|---|
| Shipped In | Ice chest + Ice pads |
| Product Description | Description Amine functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into carboxyl containing compounds or biomolecules via standard coupling techniques (DCC; EDC etc...). Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging. |
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| 1. Mark R Karver, Ralph Weissleder, Scott A Hilderbrand,. (2011-09-29) Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation.. Bioconjugate chemistry, 22 ((11)): ( 2263-2270 ). [PMID:21950520] |
