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TCO-PEG4-Val-Cit-PAB-PNP - 98%, high purity

  • ≥98%
Item Number
T597273
Grouped product items
SKUSizeAvailabilityPrice Qty
T597273-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,551.90

Val-Cit

View related series
Peptide Linkers

Basic Description

Specifications & Purity98%
Storage TempStore at -20°C
Shipped InDry ice
Product Description

TCO-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity.

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