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Tea tree oil - pharmaceutical, high purity , CAS No.68647-73-4

PharmPure™

pharmaceutical grade

CAS#: 68647-73-4
Formula: C₂₈H₆₀O₄P₂S₄Zn
Molecular Weight: 716.4
MDL number: MFCD00132409
PubChem CID: 22833361

Item Number

T111362

Grouped product items
SKU	Size	Availability	Price	Qty
T111362-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$27.90
T111362-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$106.90

Basic Description

Synonyms	68649-42-3 \| 68647-73-4 \| EINECS 272-028-3 \| zinc;diheptoxy-sulfanylidene-sulfido-lambda5-phosphane \| SCHEMBL164653 \| DTXSID30874014 \| Zinc bis(O,O-diheptyl phosphorodithioate) \| 82322-26-7
Specifications & Purity	pharmaceutical
Storage Temp	Store at 2-8°C,Protected from light
Shipped In	Wet ice
Grade	pharmaceutical grade, PharmPure™

Names and Identifiers

IUPAC Name	zinc;diheptoxy-sulfanylidene-sulfido-λ5-phosphane
INCHI	InChI=1S/2C14H31O2PS2.Zn/c21-3-5-7-9-11-13-15-17(18,19)16-14-12-10-8-6-4-2;/h23-14H2,1-2H3,(H,18,19);/q;;+2/p-2
InChi Key	ZKAQFYDDTYGBBV-UHFFFAOYSA-L
Canonical SMILES	CCCCCCCOP(=S)(OCCCCCCC)[S-].CCCCCCCOP(=S)(OCCCCCCC)[S-].[Zn+2]
Isomeric SMILES	CCCCCCCOP(=S)(OCCCCCCC)[S-].CCCCCCCOP(=S)(OCCCCCCC)[S-].[Zn+2]
WGK Germany	3
RTECS	RJ3697600
PubChem CID	22833361
Molecular Weight	716.4

Certificates

Certificate of Analysis(COA)

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8 results found

Lot Number	Certificate Type	Date	Item
K2218120	Certificate of Analysis	Nov 23, 2022	T111362
B2328260	Certificate of Analysis	Jun 08, 2021	T111362
C2314518	Certificate of Analysis	Jun 08, 2021	T111362
G2120258	Certificate of Analysis	Jun 08, 2021	T111362
G2120259	Certificate of Analysis	Jun 08, 2021	T111362
G2120305	Certificate of Analysis	Jun 08, 2021	T111362
G2120307	Certificate of Analysis	Jun 08, 2021	T111362
K2310028	Certificate of Analysis	Jun 08, 2021	T111362

Chemical and Physical Properties

Sensitivity	light & air sensitive
Refractive Index	1.478
Flash Point(°F)	147°C
Flash Point(°C)	147°C
Boil Point(°C)	165°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS09, GHS07, GHS02
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H411:Toxic to aquatic life with long lasting effects H302:Harmful if swallowed H317:May cause an allergic skin reaction H400:Very toxic to aquatic life H226:Flammable liquid and vapor H360:May damage fertility or the unborn child H304:May be fatal if swallowed and enters airways
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P271:Use only outdoors or in a well-ventilated area. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P331:Do NOT induce vomiting. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	3
RTECS	RJ3697600

Citations of This Product

1. Ting Huang, Yingbing Zhang, Li Zhao, Yu Ren, Keke Wang, Nannan Zhang, Xiaoli Zhang, Jinyi Wang, Qin Tu. (2024) Sodium hyaluronate hydrogel for wound healing and human health monitoring based on deep eutectic solvent. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 257 (128801). [PMID:38101662]
2. Li Hao, Mei Guan, Qiangcheng Zheng, Minyan Zhou, Ziting Yin, Hongjun Zhou, Xinhua Zhou. (2023) Functionalized boron nitride nanosheets conjugated with plant micronutrients as seed dressing agents towards control of bacterial wilt disease. Environmental Science-Nano, [PMID:]
3. Jinghui Zhan, Huayao Chen, Hongjun Zhou, Li Hao, Hua Xu, Xinhua Zhou. (2023) Essential oil-loaded chitosan/zinc (II) montmorillonite synergistic sustained-release system as antibacterial material. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, [PMID:]
4. Xiaohan Ge, Xueying Huang, Liping Zhou, Yi Wang. (2022) Essential oil-loaded antimicrobial and antioxidant zein/poly(lactic acid) film as active food packaging. Food Packaging and Shelf Life, 34 (100977). [PMID:]

References

1. C F Carson,T V Riley,B D Cookson. (1998-11-27) Efficacy and safety of tea tree oil as a topical antimicrobial agent.. The Journal of hospital infection, 40 ((3)): (175-178). [PMID:9830588]
2. L R Williams. (1998-11-27) Clonal production of tea tree oil high in terpinen-4-ol for use in formulations for the treatment of thrush.. Complementary therapies in nursing & midwifery, 4 ((5)): (133-136). [PMID:9830943]
3. D M Rubel,S Freeman,I A Southwell. (1998-12-05) Tea tree oil allergy: what is the offending agent? Report of three cases of tea tree oil allergy and review of the literature.. The Australasian journal of dermatology, 39 ((4)): (244-247). [PMID:9838722]
4. Linda Halcón,Kelly Milkus. (2004-11-05) Staphylococcus aureus and wounds: a review of tea tree oil as a promising antimicrobial.. American journal of infection control, 32 ((7)): (402-408). [PMID:15525915]
5. Mick Willcox. (2005-03-30) An evaluation of tea tree oil as an alternative microbicide.. Nursing times, 101 ((11)): (32-33). [PMID:15793953]
6. K A Hammer,C F Carson,T V Riley,J B Nielsen. (2005-10-26) A review of the toxicity of Melaleuca alternifolia (tea tree) oil.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 44 ((5)): (616-625). [PMID:16243420]
7. Orville Hartford,Kathryn A Zug. (2005-11-05) Tea tree oil.. Cutis, 76 ((3)): (178-180). [PMID:16268260]
8. C F Carson,K A Hammer,T V Riley. (2006-01-19) Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties.. Clinical microbiology reviews, 19 ((1)): (50-62). [PMID:16418522]
9. Tim Rutherford,Rosemary Nixon,Mei Tam,Bruce Tate. (2007-05-31) Allergy to tea tree oil: retrospective review of 41 cases with positive patch tests over 4.5 years.. The Australasian journal of dermatology, 48 ((2)): (83-87). [PMID:17535193]
10. Mikaela Ahlin,Veronika Dingizian,Ake Svenssson. (2011-09-20) [High frequency of contact allergy caused by alternative medicine substances. Tea tree oil tops the list].. Lakartidningen, 108 ((32-33)): (1487-1490). [PMID:21922939]
11. Katherine A Hammer,Christine F Carson,Thomas V Riley. (2011-11-16) Effects of Melaleuca alternifolia (tea tree) essential oil and the major monoterpene component terpinen-4-ol on the development of single- and multistep antibiotic resistance and antimicrobial susceptibility.. Antimicrobial agents and chemotherapy, 56 ((2)): (909-915). [PMID:22083482]
12. Johanna Rudbäck,Moa Andresen Bergström,Anna Börje,Ulrika Nilsson,Ann-Therese Karlberg. (2012-01-19) α-Terpinene, an antioxidant in tea tree oil, autoxidizes rapidly to skin allergens on air exposure.. Chemical research in toxicology, 25 ((3)): (713-721). [PMID:22250748]
13. Biljana Todorović,Svetlana Milijasević-Marčić,Ivana Potočnik,Miloš Stepanović,Emil Rekanović,Ljiljana Nikolić-Bujanović,Milan Cekerevac. (2012-03-02) In vitro activity of antimicrobial agents against Pseudomonas tolaasii, pathogen of cultivated button mushroom.. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 47 ((3)): (175-179). [PMID:22375589]
14. Eric Markum,John Baillie. (2012-03-08) Combination of essential oil of Melaleuca alternifolia and iodine in the treatment of molluscum contagiosum in children.. Journal of drugs in dermatology : JDD, 11 ((3)): (349-354). [PMID:22395586]
15. P J James,J T Callander. (2012-03-09) Bioactivity of tea tree oil from Melaleuca alternifolia against sheep lice (Bovicola ovis Schrank) in vitro.. Veterinary parasitology, 187 ((3-4)): (498-504). [PMID:22398149]
16. Nader Pazyar,Reza Yaghoobi. (2012-04-05) Tea tree oil as a novel antipsoriasis weapon.. Skin pharmacology and physiology, 25 ((3)): (162-163). [PMID:22473218]
17. N Joksimovic,G Spasovski,V Joksimovic,V Andreevski,C Zuccari,C F Omini. (2012-04-12) Efficacy and tolerability of hyaluronic acid, tea tree oil and methyl-sulfonyl-methane in a new gel medical device for treatment of haemorrhoids in a double-blind, placebo-controlled clinical trial.. Updates in surgery, 64 ((3)): (195-201). [PMID:22492249]
18. Jesus A Cuaron,Santosh Dulal,Yang Song,Atul K Singh,Cesar E Montelongo,Wanqin Yu,Vijayaraj Nagarajan,Radheshyam K Jayaswal,Brian J Wilkinson,John E Gustafson. (2012-05-24) Tea tree oil-induced transcriptional alterations in Staphylococcus aureus.. Phytotherapy research : PTR, 27 ((3)): (390-396). [PMID:22619070]
19. Li-ming Sun,Chen-lu Zhang,Ping Li. (2012-05-30) Characterization, antibiofilm, and mechanism of action of novel PEG-stabilized lipid nanoparticles loaded with terpinen-4-ol.. Journal of agricultural and food chemistry, 60 ((24)): (6150-6156). [PMID:22640226]
20. David Larson,Sharon E Jacob. (2012-06-02) Tea tree oil.. Dermatitis : contact, atopic, occupational, drug, 23 ((1)): (48-49). [PMID:22653070]
21. Kentaro Ninomiya,Naho Maruyama,Shigeharu Inoue,Hiroko Ishibashi,Toshio Takizawa,Haruyuki Oshima,Shigeru Abe. (2012-06-13) The essential oil of Melaleuca alternifolia (tea tree oil) and its main component, terpinen-4-ol protect mice from experimental oral candidiasis.. Biological & pharmaceutical bulletin, 35 ((6)): (861-865). [PMID:22687476]
22. Demelza J Ireland,Sara J Greay,Cornelia M Hooper,Haydn T Kissick,Pierre Filion,Thomas V Riley,Manfred W Beilharz. (2012-06-26) Topically applied Melaleuca alternifolia (tea tree) oil causes direct anti-cancer cytotoxicity in subcutaneous tumour bearing mice.. Journal of dermatological science, 67 ((2)): (120-129). [PMID:22727730]
23. Ibrahim Taga,Christopher Q Lan,Illimar Altosaar. (2012-07-18) Plant essential oils and mastitis disease: their potential inhibitory effects on pro-inflammatory cytokine production in response to bacteria related inflammation.. Natural product communications, 7 ((5)): (675-682). [PMID:22799106]
24. Emanuela Di Campli,Soraya Di Bartolomeo,Patricia Delli Pizzi,Mara Di Giulio,Rossella Grande,Antonia Nostro,Luigina Cellini. (2012-08-01) Activity of tea tree oil and nerolidol alone or in combination against Pediculus capitis (head lice) and its eggs.. Parasitology research, 111 ((5)): (1985-1992). [PMID:22847279]
25. Purwatiningsih,N Heather,E Hassan. (2012-08-30) Efficacy of Leptospermum petersonii oil, on Plutella xylostella, and its parasitoid, Trichogramma pretiosum.. Journal of economic entomology, 105 ((4)): (1379-1384). [PMID:22928319]
26. Marcel Forrer,Eva M Kulik,Andreas Filippi,Tuomas Waltimo. (2012-09-04) The antimicrobial activity of alpha-bisabolol and tea tree oil against Solobacterium moorei, a Gram-positive bacterium associated with halitosis.. Archives of oral biology, 58 ((1)): (10-16). [PMID:22939370]
27. Michael L Spector,Mark Fischer,Deborah V Dawson,David C Holmes,Colleen Kummet,Nicole L Nisly,Karen A K Baker. (2012-09-05) Complementary and alternative medicine usage by patients of a dental school clinic.. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry, 32 ((5)): (177-183). [PMID:22943769]
28. Hyun Koo,Tae Hyung Kim,Kyoung Woo Kim,Sung Wook Wee,Yeoun Sook Chun,Jae Chan Kim. (2012-12-21) Ocular surface discomfort and Demodex: effect of tea tree oil eyelid scrub in Demodex blepharitis.. Journal of Korean medical science, 27 ((12)): (1574-1579). [PMID:23255861]
29. Kunj G Patel,V K Raju. (2013-06-27) Ocular demodicosis.. The West Virginia medical journal, 109 ((3)): (16-18). [PMID:23798275]
30. J A Terriquez,S A Klotz,E A Meister,J H Klotz,J O Schmidt. (2013-06-28) Repellency of DEET, picaridin, and three essential oils to Triatoma rubida (Hemiptera: Reduviidae: Triatominae).. Journal of medical entomology, 50 ((3)): (664-667). [PMID:23802464]
31. Christine F Carson,Katherine A Hammer,Ian A Southwell,Thomas V Riley. (2012-01-01) [The side effects are exaggerated].. Lakartidningen, 109 ((32-33)): (1419-1419). [PMID:23909012]
32. Matheus D Baldissera,Aleksandro S Da Silva,Camila B Oliveira,Roberto C V Santos,Rodrigo A Vaucher,Renata P Raffin,Patrícia Gomes,Maria G C Dambros,Luiz C Miletti,Aline A Boligon,Margareth L Athayde,Silvia G Monteiro. (2014-03-25) Trypanocidal action of tea tree oil (Melaleuca alternifolia) against Trypanosoma evansi in vitro and in vivo used mice as experimental model.. Experimental parasitology, 141 (21-27). [PMID:24657576]
33. Diane C Homeyer,Carlos J Sanchez,Katrin Mende,Miriam L Beckius,Clinton K Murray,Joseph C Wenke,Kevin S Akers. (2015-01-30) In vitro activity of Melaleuca alternifolia (tea tree) oil on filamentous fungi and toxicity to human cells.. Medical mycology, 53 ((3)): (285-294). [PMID:25631479]
34. E Ernst,A Huntley. (2000-05-09) Tea tree oil: a systematic review of randomized clinical trials.. Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine, 7 ((1)): (17-20). [PMID:10800248]
35. Glen H Crawford,Joslyn R Sciacca,William D James. (2004-10-12) Tea tree oil: cutaneous effects of the extracted oil of Melaleuca alternifolia.. Dermatitis : contact, atopic, occupational, drug, 15 ((2)): (59-66). [PMID:15473330]
36. Deborah Flaxman,Peter Griffiths. (2005-04-13) Is tea tree oil effective at eradicating MRSA colonization? A review.. British journal of community nursing, 10 ((3)): (123-126). [PMID:15824699]
37. P J James,J T Callander. (2012-05-15) Dipping and jetting with tea tree (Melaleuca alternifolia) oil formulations control lice (Bovicola ovis) on sheep.. Veterinary parasitology, 189 ((2-4)): (338-343). [PMID:22579852]
38. M Cháfer,L Sánchez-González,Ch González-Martínez,A Chiralt. (2012-08-07) Fungal decay and shelf life of oranges coated with chitosan and bergamot, thyme, and tea tree essential oils.. Journal of food science, 77 ((8)): (E182-E187). [PMID:22860582]
39. Mohd Aamir Mirza,Sayeed Ahmad,Md Nasar Mallick,Nikhat Manzoor,Sushama Talegaonkar,Zeenat Iqbal. (2012-12-04) Development of a novel synergistic thermosensitive gel for vaginal candidiasis: an in vitro, in vivo evaluation.. Colloids and surfaces. B, Biointerfaces, 103 (275-282). [PMID:23201748]
40. G Tirabassi,L Giovannini,F Paggi,G Panin,F Panin,R Papa,M Boscaro,G Balercia. (2012-12-06) Possible efficacy of Lavender and Tea tree oils in the treatment of young women affected by mild idiopathic hirsutism.. Journal of endocrinological investigation, 36 ((1)): (50-54). [PMID:23211454]
41. Benjamin Savareear,Matthew R Jacobs,Robert A Shellie. (2014-09-25) Multiplexed dual first-dimension comprehensive two-dimensional gas chromatography-mass spectrometry with contra-directional thermal modulation.. Journal of chromatography. A, 1365 (183-190). [PMID:25249490]
42. Ting Huang, Yingbing Zhang, Li Zhao, Yu Ren, Keke Wang, Nannan Zhang, Xiaoli Zhang, Jinyi Wang, Qin Tu. (2024) Sodium hyaluronate hydrogel for wound healing and human health monitoring based on deep eutectic solvent. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 257 (128801). [PMID:38101662]
43. Li Hao, Mei Guan, Qiangcheng Zheng, Minyan Zhou, Ziting Yin, Hongjun Zhou, Xinhua Zhou. (2023) Functionalized boron nitride nanosheets conjugated with plant micronutrients as seed dressing agents towards control of bacterial wilt disease. Environmental Science-Nano, [PMID:]
44. Jinghui Zhan, Huayao Chen, Hongjun Zhou, Li Hao, Hua Xu, Xinhua Zhou. (2023) Essential oil-loaded chitosan/zinc (II) montmorillonite synergistic sustained-release system as antibacterial material. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, [PMID:]
45. Xiaohan Ge, Xueying Huang, Liping Zhou, Yi Wang. (2022) Essential oil-loaded antimicrobial and antioxidant zein/poly(lactic acid) film as active food packaging. Food Packaging and Shelf Life, 34 (100977). [PMID:]

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