Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab183440-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $59.90 | |
| Ab183440-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $259.90 | |
| Ab183440-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $589.90 | |
| Ab183440-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $929.90 |
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Teneliximab (anti-CD40) - Primary antibody, specific to CD40, Human IgG1 |
|---|---|
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot |
| Specificity | CD40 |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | PARTIAL AGONIST |
| Mechanism of action | PARTIAL AGONIST of Tumor necrosis factor receptor superfamily member 5 partial agonist |
| Product Description | Teneliximab (anti-CD40) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (anti-CD40) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 146.06 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 299423-37-3 |
Teneliximab (anti-CD40) (Ab183440) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD40 (red) with Teneliximab (anti-CD40) (Ab183440). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Teneliximab (anti-CD40) (Ab183440) - Flow Cytometry
Flow Cytometry analysis of U-2OS cells labelling CD40 (red) with Teneliximab (anti-CD40) (Ab183440). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Teneliximab (anti-CD40) (Ab183440) - ELISA
Immobilized Recombinant Human CD40 Protein (rp144000) at 1.0 μg/mL can bind Teneliximab (anti-CD40) (Ab183440) with the EC50 of 11.50 ng/mL.
Teneliximab (anti-CD40) (Ab183440) - SEC
The purity of Teneliximab (anti-CD40) (Ab183440) is more than 95% verified by HPLC.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0505701 | Certificate of Analysis | May 16, 2024 | Ab183440 |
| ZJ24F0505702 | Certificate of Analysis | May 16, 2024 | Ab183440 |
| ZJ24F0505703 | Certificate of Analysis | May 16, 2024 | Ab183440 |
