Click Here for 5% Off Your First Aladdin Purchase!

tert-Butylhydroquinone - 98%, high purity , CAS No.1948-33-0

  • ≥98%
Item Number
B105351
Grouped product items
SKUSizeAvailabilityPrice Qty
B105351-25g
25g
In stock
$17.90
B105351-100g
100g
In stock
$39.90
B105351-500g
500g
In stock
$99.90

Basic Description

Synonymstert-Butylhydroquinone|1948-33-0|TBHQ|2-tert-Butylhydroquinone|2-tert-butylbenzene-1,4-diol|T-BUTYLHYDROQUINONE|MTBHQ|t-Butyl hydroquinone|2-t-Butylhydroquinone|Mono-tert-butylhydroquinone|Sustane|2-tert-Butyl-1,4-benzenediol|Mono-tertiarybutylhydroquinon
Specifications & Purity≥98%
Storage TempRoom temperature,Argon charged
Shipped InNormal
Product Description

tert-Butylhydroquinone (TBHQ) is a phenolic antioxidant. TBHQ is frequently used as a food preservative. In low concentrations it shows cytoprotective qualities while at higher concentrations it exhibits cytotoxic behavior.
TBHQ was used to study the inactivation of barotolerant strains of Listeria monocytogenes and Escherichia coli.Environment friendly electrode materials for supercapacitors were attained by decorating the surface of graphene nanosheets with TBHQ.

Associated Targets

ESR1 Tclin Estrogen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

VDR Tclin Vitamin D3 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

LMNA Tbio Prelamin-A/C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALOX15 Tchem Arachidonate 15-lipoxygenase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC2 Tchem Canalicular multispecific organic anion transporter 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1I2 Tchem Nuclear receptor subfamily 1 group I member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TYR Tclin Tyrosinase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AHR Tclin Aryl hydrocarbon receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

THRB Tclin Thyroid hormone receptor beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTT Tchem Huntingtin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GLS Tchem Glutaminase kidney isoform, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARD Tchem Peroxisome proliferator-activated receptor delta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CXCL8 Tchem Interleukin-8 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KEAP1 Tclin Kelch-like ECH-associated protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC1 Tchem Multidrug resistance-associated protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488182199
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488182199
IUPAC Name 2-tert-butylbenzene-1,4-diol
INCHI InChI=1S/C10H14O2/c1-10(2,3)8-6-7(11)4-5-9(8)12/h4-6,11-12H,1-3H3
InChi Key BGNXCDMCOKJUMV-UHFFFAOYSA-N
Canonical SMILES CC(C)(C)C1=C(C=CC(=C1)O)O
Isomeric SMILES CC(C)(C)C1=C(C=CC(=C1)O)O
WGK Germany 3
RTECS MX4375000
PubChem CID 16043
Molecular Weight 166.22
Beilstein 637923
Reaxy-Rn 637923

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

24 results found

Lot NumberCertificate TypeDateItem
H2412293Certificate of AnalysisAug 01, 2024 B105351
H2412279Certificate of AnalysisAug 01, 2024 B105351
H2412274Certificate of AnalysisAug 01, 2024 B105351
H2402124Certificate of AnalysisJun 14, 2024 B105351
H2402122Certificate of AnalysisJun 14, 2024 B105351
H2402123Certificate of AnalysisJun 14, 2024 B105351
G2220266Certificate of AnalysisApr 07, 2024 B105351
G2220267Certificate of AnalysisApr 07, 2024 B105351
G2220268Certificate of AnalysisApr 07, 2024 B105351
E2230228Certificate of AnalysisMar 19, 2024 B105351
E2230240Certificate of AnalysisMar 19, 2024 B105351
E2230244Certificate of AnalysisMar 19, 2024 B105351
I2129283Certificate of AnalysisJul 11, 2023 B105351
I2129025Certificate of AnalysisJul 11, 2023 B105351
D2114326Certificate of AnalysisJan 13, 2023 B105351
D2114321Certificate of AnalysisJan 13, 2023 B105351
K2230275Certificate of AnalysisOct 09, 2022 B105351
K2230281Certificate of AnalysisOct 09, 2022 B105351
K2230290Certificate of AnalysisOct 09, 2022 B105351
K2230291Certificate of AnalysisOct 09, 2022 B105351
E2324177Certificate of AnalysisOct 09, 2022 B105351
C2309042Certificate of AnalysisJun 18, 2022 B105351
C2309041Certificate of AnalysisJun 18, 2022 B105351
G2008041Certificate of AnalysisApr 26, 2022 B105351

more

Chemical and Physical Properties

SolubilitySlightly soluble in water(10g/L).
SensitivityMoisture & air sensitive.
Flash Point(°F)195.8 °F
Flash Point(°C)91 °C
Boil Point(°C)295°C
Melt Point(°C)127°C

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

H317:May cause an allergic skin reaction

H312:Harmful in contact with skin

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

H302+H312:Harmful if swallowed or in contact with skin

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS MX4375000
Reaxy-Rn 637923

Related Documents

References

1. Gao Q et al..  (2019)  SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC..  Cell Death Differ,      [PMID:31367013]
2. G J van Esch.  (1986-10-01)  Toxicology of tert-butylhydroquinone (TBHQ)..  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,  24  ((10-11)): (1063-1065).  [PMID:3542758]
3. Maria-João R P Queiroz,Isabel C F R Ferreira,Ricardo C Calhelha,Letícia M Estevinho.  (2006-12-15)  Synthesis and antioxidant activity evaluation of new 7-aryl or 7-heteroarylamino-2,3-dimethylbenzo[b]thiophenes obtained by Buchwald-Hartwig C-N cross-coupling..  Bioorganic & medicinal chemistry,  15  ((4)): (1788-1794).  [PMID:17166720]
4. Yoon-Kyung Chung,Ahmed E Yousef.  (2008-07-08)  Inactivation of barotolerant strains of Listeria monocytogenes and Escherichia coli O157:H7 by ultra high pressure and tert-butylhydroquinone combination..  Journal of microbiology (Seoul, Korea),  46  ((3)): (289-294).  [PMID:18604498]
5. Yunbao Liu,Muraleedharan G Nair.  (2010-06-23)  An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds..  Journal of natural products,  73  ((7)): (1193-1195).  [PMID:20565070]
6. Christopher Elam,Michael Lape,Joel Deye,Jodie Zultowsky,David T Stanton,Stefan Paula.  (2011-03-01)  Discovery of novel SERCA inhibitors by virtual screening of a large compound library..  European journal of medicinal chemistry,  46  ((5)): (1512-1523).  [PMID:21353727]
7. Cheryl E Rockwell,Mingcai Zhang,Patrick E Fields,Curtis D Klaassen.  (2012-01-18)  Th2 skewing by activation of Nrf2 in CD4(+) T cells..  Journal of immunology (Baltimore, Md. : 1950),  188  ((4)): (1630-1637).  [PMID:22250088]
8. Albert Braeuning,Silvia Vetter,Silvia Orsetti,Michael Schwarz.  (2012-04-03)  Paradoxical cytotoxicity of tert-butylhydroquinone in vitro: What kills the untreated cells?.  Archives of toxicology,  86  ((9)): (1481-1487).  [PMID:22466069]
9. Toshiyuki Matsunaga,Satoshi Endo,Mayuko Takemura,Midori Soda,Keiko Yamamura,Kazuo Tajima,Takeshi Miura,Tomoyuki Terada,Ossama El-Kabbani,Akira Hara.  (2012-04-14)  Reduction of cytotoxic p-quinone metabolites of tert-butylhydroquinone by human aldo-keto reductase (AKR) 1B10..  Drug metabolism and pharmacokinetics,  27  ((5)): (553-558).  [PMID:22498646]
10. Saelooom Lee,Min-Jin Lim,Mi-Hyoung Kim,Chi-Ho Yu,Yeon-Sook Yun,Jiyeon Ahn,Jie-Young Song.  (2012-06-12)  An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses..  Free radical biology & medicine,  53  ((4)): (807-816).  [PMID:22684019]
11. Michael J Steinbaugh,Liou Y Sun,Andrzej Bartke,Richard A Miller.  (2012-06-14)  Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan..  American journal of physiology. Endocrinology and metabolism,  303  ((4)): (E488-E495).  [PMID:22693205]
12. Kai Takaya,Takafumi Suzuki,Hozumi Motohashi,Ko Onodera,Susumu Satomi,Thomas W Kensler,Masayuki Yamamoto.  (2012-06-27)  Validation of the multiple sensor mechanism of the Keap1-Nrf2 system..  Free radical biology & medicine,  53  ((4)): (817-827).  [PMID:22732183]
13. Susana Criado,Carolina Allevi,Norman A García.  (2012-06-27)  Visible-light-promoted degradation of the antioxidants propyl gallate and t-butylhydroquinone: mechanistic aspects..  Redox report : communications in free radical research,  17  ((3)): (131-138).  [PMID:22732940]
14. Alex Bliu,Michele Lemieux,Changgui Li,Xuguang Li,Junzhi Wang,Aaron Farnsworth.  (2012-07-04)  Modifying the thermostability of inactivated influenza vaccines..  Vaccine,  30  ((37)): (5506-5511).  [PMID:22749603]
15. Parmvir K Bahia,Victoria Pugh,Kimberley Hoyland,Victoria Hensley,Marcus Rattray,Robert J Williams.  (2012-07-19)  Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activity..  Journal of neurochemistry,  123  ((1)): (182-191).  [PMID:22804756]
16. J N Saykally,L Rachmany,H Hatic,A Shaer,V Rubovitch,C G Pick,B A Citron.  (2012-08-15)  The nuclear factor erythroid 2-like 2 activator, tert-butylhydroquinone, improves cognitive performance in mice after mild traumatic brain injury..  Neuroscience,  223  (305-314).  [PMID:22890082]
17. Thiago F Tormin,Rafael R Cunha,Eduardo M Richter,Rodrigo A A Munoz.  (2012-09-13)  Fast simultaneous determination of BHA and TBHQ antioxidants in biodiesel by batch injection analysis using pulsed-amperometric detection..  Talanta,  99  (527-531).  [PMID:22967589]
18. Robert C Lyon,Dan Li,Gail McGarvie,Elizabeth M Ellis.  (2012-10-23)  Aldo-keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells..  Neurochemistry international,  62  ((1)): (113-121).  [PMID:23084985]
19. Caroline S Kinter,Jillian M Lundie,Halee Patel,Paul M Rindler,Luke I Szweda,Michael Kinter.  (2012-11-21)  A quantitative proteomic profile of the Nrf2-mediated antioxidant response of macrophages to oxidized LDL determined by multiplexed selected reaction monitoring..  PloS one,  ((11)): (e50016-e50016).  [PMID:23166812]
20. Elizabeth R Macari,Emily K Schaeffer,Rachel J West,Christopher H Lowrey.  (2012-12-12)  Simvastatin and t-butylhydroquinone suppress KLF1 and BCL11A gene expression and additively increase fetal hemoglobin in primary human erythroid cells..  Blood,  121  ((5)): (830-839).  [PMID:23223429]
21. Kyeong-Ah Jung,Bo-Hyun Choi,Chang-Won Nam,Mingu Song,Sang-Tae Kim,Joo Young Lee,Mi-Kyoung Kwak.  (2013-01-12)  Identification of aldo-keto reductases as NRF2-target marker genes in human cells..  Toxicology letters,  218  ((1)): (39-49).  [PMID:23305850]
22. Shan He,Xu-Fang Liang,Jian Sun,Dan Shen.  (2013-01-29)  Induction of liver GST transcriptions by tert-butylhydroquinone reduced microcystin-LR accumulation in Nile tilapia (Oreochromis niloticus)..  Ecotoxicology and environmental safety,  90  (128-135).  [PMID:23352130]
23. Qing Zhong,Manish Mishra,Renu A Kowluru.  (2013-05-02)  Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy..  Investigative ophthalmology & visual science,  54  ((6)): (3941-3948).  [PMID:23633659]
24. Songtao Li,Jiaxin Li,Chen Shen,Ximei Zhang,Shan Sun,Michael Cho,Changhao Sun,Zhenyuan Song.  (2013-09-24)  tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation..  Biochimica et biophysica acta,  1841  ((1)): (22-33).  [PMID:24055888]
25. Karelle Bénardais,Refik Pul,Vikramjeet Singh,Thomas Skripuletz,De-Hyung Lee,Ralf A Linker,Viktoria Gudi,Martin Stangel.  (2013-10-01)  Effects of fumaric acid esters on blood-brain barrier tight junction proteins..  Neuroscience letters,  555  (165-170).  [PMID:24076006]
26. Emilio Siendones,Sara SantaCruz-Calvo,Alejandro Martín-Montalvo,María V Cascajo,Julia Ariza,Guillermo López-Lluch,José M Villalba,Cécile Acquaviva-Bourdain,Emmanuel Roze,Michel Bernier,Rafael de Cabo,Plácido Navas.  (2014-01-24)  Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2..  Antioxidants & redox signaling,  21  ((12)): (1708-1725).  [PMID:24450884]
27. Heng Lin,Hsiao-Fen Li,Hsi-Hsien Chen,Pei-Fang Lai,Shu-Hui Juan,Jin-Jer Chen,Ching-Feng Cheng.  (2014-02-20)  Activating transcription factor 3 protects against pressure-overload heart failure via the autophagy molecule Beclin-1 pathway..  Molecular pharmacology,  85  ((5)): (682-691).  [PMID:24550138]
28. Claudie Morzadec,Mélinda Macoch,Lydie Sparfel,Saadia Kerdine-Römer,Olivier Fardel,Laurent Vernhet.  (2014-03-19)  Nrf2 expression and activity in human T lymphocytes: stimulation by T cell receptor activation and priming by inorganic arsenic and tert-butylhydroquinone..  Free radical biology & medicine,  71  (133-145).  [PMID:24632381]
29. Jiwon Jang,Yidi Wang,Hyung-Seok Kim,Matthew A Lalli,Kenneth S Kosik.  (2014-06-05)  Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells..  Stem cells (Dayton, Ohio),  32  ((10)): (2616-2625).  [PMID:24895273]
30. Laura Gambari,Gina Lisignoli,Luca Cattini,Cristina Manferdini,Andrea Facchini,Francesco Grassi.  (2014-07-08)  Sodium hydrosulfide inhibits the differentiation of osteoclast progenitor cells via NRF2-dependent mechanism..  Pharmacological research,  87  (99-112).  [PMID:24998607]
31. M Valenzuela,C Glorieux,J Stockis,B Sid,J M Sandoval,K B Felipe,M R Kviecinski,J Verrax,P Buc Calderon.  (2014-07-09)  Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells..  British journal of cancer,  111  ((5)): (874-882).  [PMID:25003661]
32. Nadiya Ekbatani Amlashi,Mohammad Reza Hadjmohammadi,Seyed Saman Seyed Jafar Nazari.  (2014-08-26)  Water-contained surfactant-based vortex-assisted microextraction method combined with liquid chromatography for determination of synthetic antioxidants from edible oil..  Journal of chromatography. A,  1361  (9-15).  [PMID:25151039]
33. Xin Chen,Xianping Shi,Chong Zhao,Xiaofen Li,Xiaoying Lan,Shouting Liu,Hongbiao Huang,Ningning Liu,Siyan Liao,Dan Zang,Wenbin Song,Quentin Liu,Bing Z Carter,Q Ping Dou,Xuejun Wang,Jinbao Liu.  (2014-09-07)  Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms..  Oncotarget,  ((19)): (9118-9132).  [PMID:25193854]
34. Hae-Ryung Park,Rita Loch-Caruso.  (2014-10-12)  Protective effect of nuclear factor E2-related factor 2 on inflammatory cytokine response to brominated diphenyl ether-47 in the HTR-8/SVneo human first trimester extravillous trophoblast cell line..  Toxicology and applied pharmacology,  281  ((1)): (67-77).  [PMID:25305463]
35. Ha-Neul Choi,Min-Jung Kang,Soo-Jin Lee,Jung-In Kim.  (2014-10-18)  Ameliorative effect of myricetin on insulin resistance in mice fed a high-fat, high-sucrose diet..  Nutrition research and practice,  ((5)): (544-549).  [PMID:25324935]
36. Bo Zhang,Xiao-Qin Wang,Han-Yin Chen,Bin-Hua Liu.  (2014-10-25)  Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress..  Journal of pharmacological sciences,  126  ((3)): (216-229).  [PMID:25341683]
37. Ge Liu,Beverly Sara Mühlhäusler,Robert Alan Gibson.  (2014-12-03)  A method for long term stabilisation of long chain polyunsaturated fatty acids in dried blood spots and its clinical application..  Prostaglandins, leukotrienes, and essential fatty acids,  91  ((6)): (251-260).  [PMID:25451557]
38. Ratchanee Kongkachuichai,Rin Charoensiri,Kameelah Yakoh,Aurawan Kringkasemsee,Poonsub Insung.  (2014-12-04)  Nutrients value and antioxidant content of indigenous vegetables from Southern Thailand..  Food chemistry,  173  (838-846).  [PMID:25466097]
39. Da-Min Gu,Pei-Hua Lu,Ke Zhang,Xiang Wang,Min Sun,Guo-Qian Chen,Qiong Wang.  (2015-01-15)  EGFR mediates astragaloside IV-induced Nrf2 activation to protect cortical neurons against in vitro ischemia/reperfusion damages..  Biochemical and biophysical research communications,  457  ((3)): (391-397).  [PMID:25582778]
40. Leina Ma,Jia Liu,Xinling Zhang,Jieqiong Qi,Wengong Yu,Yuchao Gu.  (2015-02-19)  p38 MAPK-dependent Nrf2 induction enhances the resistance of glioma cells against TMZ..  Medical oncology (Northwood, London, England),  32  ((3)): (69-69).  [PMID:25691294]
41. Mi-Nam Kim,Juhee Choi,Han-Wook Ryu,Kwon-Yul Ryu.  (2015-02-24)  Disruption of polyubiquitin gene Ubc leads to attenuated resistance against arsenite-induced toxicity in mouse embryonic fibroblasts..  Biochimica et biophysica acta,  1853  ((5)): (996-1009).  [PMID:25701757]
42. Huilin Liu,Dan Wu,Yingli Liu,Huijuan Zhang,Tiezheng Ma,Ainasi Aidaerhan,Jing Wang,Baoguo Sun.  (2015-02-24)  Application of an optosensing chip based on molecularly imprinted polymer coated quantum dots for the highly selective and sensitive determination of sesamol in sesame oils..  Journal of agricultural and food chemistry,  63  ((9)): (2545-2549).  [PMID:25706413]
43. Nora L Krutz,Jennifer Hennen,Corinna Korb,Mario T Schellenberger,G Frank Gerberick,Brunhilde Blömeke.  (2015-07-18)  Activation of the Endoperoxide Ascaridole Modulates Its Sensitizing Capacity..  Toxicological sciences : an official journal of the Society of Toxicology,  147  ((2)): (515-523).  [PMID:26185204]
44. Marie S Ramsvik,Bodil Bjørndal,Inge Bruheim,Pavol Bohov,Rolf K Berge.  (2015-07-21)  A Phospholipid-Protein Complex from Krill with Antioxidative and Immunomodulating Properties Reduced Plasma Triacylglycerol and Hepatic Lipogenesis in Rats..  Marine drugs,  13  ((7)): (4375-4397).  [PMID:26193284]
45. Stephen Orena,Jennifer Owen,Fuxia Jin,Morgan Fabian,Nicholas D Gillitt,Steven H Zeisel.  (2015-08-01)  Extracts of Fruits and Vegetables Activate the Antioxidant Response Element in IMR-32 Cells..  The Journal of nutrition,  145  ((9)): (2006-2011).  [PMID:26224749]
46. Yu Kigoshi,Tomomi Fukuda,Tomoyuki Endo,Nami Hayasaka,Shun-ichiro Iemura,Toru Natsume,Fuminori Tsuruta,Tomoki Chiba.  (2015-08-05)  CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2..  Scientific reports,  (12857-12857).  [PMID:26238671]
47. Hayato Maeda,Shogo Kanno,Mei Kodate,Masashi Hosokawa,Kazuo Miyashita.  (2015-08-08)  Fucoxanthinol, Metabolite of Fucoxanthin, Improves Obesity-Induced Inflammation in Adipocyte Cells..  Marine drugs,  13  ((8)): (4799-4813).  [PMID:26248075]
48. Chuan-rui Zhang,Ettannil Jayashre,Paramasivam Suresh Kumar,Muraleedharan G Nair.  (2015-10-06)  Antioxidant and Antiinflammatory Compounds in Nutmeg (Myristicafragrans) Pericarp as Determined by in vitro Assays..  Natural product communications,  10  ((8)): (1399-1402).  [PMID:26434127]
49. Hitoshi Murata,Hitoshi Takamatsu,Sulai Liu,Ken Kataoka,Nam-Ho Huh,Masakiyo Sakaguchi.  (2015-11-12)  NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions..  PloS one,  10  ((11)): (e0142438-e0142438).  [PMID:26555609]
50. Bahaderjeet Singh,Prince Sharma,Arun Kumar,Pooja Chadha,Ramandeep Kaur,Amarjeet Kaur.  (2016-10-11)  Antioxidant and in vivo genoprotective effects of phenolic compounds identified from an endophytic Cladosporium velox and their relationship with its host plant Tinospora cordifolia..  Journal of ethnopharmacology,  194  (450-456).  [PMID:27721051]
51. Aijaz Ahmad Dar,Laurence S Romsted,Nighat Nazir,Yongliang Zhang,Xiang Gao,Qing Gu,Changyao Liu.  (2017-06-20)  A novel combined chemical kinetic and trapping method for probing the relationships between chemical reactivity and interfacial H.  Physical chemistry chemical physics : PCCP,  19  ((35)): (23747-23761).  [PMID:28627562]
52. Andrea Flores Burroughs,Sylvia Eluhu,Diva Whalen,J Shawn Goodwin,Amos M Sakwe,Ifeanyi J Arinze.  (2018-05-29)  PML-Nuclear Bodies Regulate the Stability of the Fusion Protein Dendra2-Nrf2 in the Nucleus..  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology,  47  ((2)): (800-816).  [PMID:29807365]
53. Anna De Blasio,Riccardo Di Fiore,Giovanni Pratelli,Rosa Drago-Ferrante,Christian Saliba,Shawn Baldacchino,Godfrey Grech,Christian Scerri,Renza Vento,Giovanni Tesoriere.  (2019-07-18)  A loop involving NRF2, miR-29b-1-5p and AKT, regulates cell fate of MDA-MB-231 triple-negative breast cancer cells..  Journal of cellular physiology,  235  ((2)): (629-637).  [PMID:31313842]
54. Larissa Bezerra Dos Santos,Flávia Carolina Favero,Mário Henrique Conde,Mariana Green Freitas,Vanessa Samúdio Santos-Zanuncio,Carlos Alexandre Carollo,Fernando de Almeida Borges.  (2020-04-07)  Clinical safety of lauric acid for cattle and its in vitro and in vivo efficacy against Rhipicephalus microplus..  Veterinary parasitology,  280  (109095-109095).  [PMID:32251919]
55. Upayan Patra,Urbi Mukhopadhyay,Arpita Mukherjee,Rakesh Sarkar,Mamta Chawla-Sarkar.  (2020-04-24)  Progressive Rotavirus Infection Downregulates Redox-Sensitive Transcription Factor Nrf2 and Nrf2-Driven Transcription Units..  Oxidative medicine and cellular longevity,  2020  (7289120-7289120).  [PMID:32322337]
56. Weijian Zhang,Hao Xiong,Jiaqi Pang,Zhongwu Su,Lan Lai,Hanqing Lin,Bingquan Jian,Wuhui He,Haidi Yang,Yiqing Zheng.  (2020-05-20)  Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production..  Toxicology letters,  331  (1-10).  [PMID:32428544]
57. A K Rodríguez-Hernández,J D Pérez-Martínez,J A Gallegos-Infante,J F Toro-Vazquez,J J Ornelas-Paz.  (2020-11-14)  Rheological properties of ethyl cellulose-monoglyceride-candelilla wax oleogel vis-a-vis edible shortenings..  Carbohydrate polymers,  252  (117171-117171).  [PMID:33183620]
58. Negar Gharavi,Susan Haggarty,Ayman O S El-Kadi.  (2007-02-03)  Chemoprotective and carcinogenic effects of tert-butylhydroquinone and its metabolites..  Current drug metabolism,  ((1)): (1-7).  [PMID:17266519]
59. Huang-Hui Chen,Yu-Tsen Chen,Yen-Wen Huang,Hui-Ju Tsai,Ching-Chuan Kuo.  (2012-01-17)  4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling..  Free radical biology & medicine,  52  ((6)): (1054-1066).  [PMID:22245092]
60. Reza Farhoosh,Mohammad Hossein Haddad Khodaparast,Ali Sharif,Atefeh Zamani-Ghalehshahi,Seyedeh-Zohreh Hoseini-Yazdi.  (2012-05-18)  Oxidative stability of virgin olive oil as affected by the bene unsaponifiable matters and tertiary-butylhydroquinone..  Journal of food science,  77  ((6)): (C697-C702).  [PMID:22591339]
61. Bo Yeon Shin,So Hee Jin,Il Je Cho,Sung Hwan Ki.  (2012-07-04)  Nrf2-ARE pathway regulates induction of Sestrin-2 expression..  Free radical biology & medicine,  53  ((4)): (834-841).  [PMID:22749810]
62. Huangyuan Li,Siying Wu,Zhangjing Wang,Wei Lin,Chenzi Zhang,Bin Huang.  (2012-09-18)  Neuroprotective effects of tert-butylhydroquinone on paraquat-induced dopaminergic cell degeneration in C57BL/6 mice and in PC12 cells..  Archives of toxicology,  86  ((11)): (1729-1740).  [PMID:22983789]
63. Dong Li,Yaqi Chen,Yu Zhang,Baiyi Lu,Cheng Jin,Xiaoqin Wu,Ying Zhang.  (2012-10-13)  Study on mitigation of acrylamide formation in cookies by 5 antioxidants..  Journal of food science,  77  ((11)): (C1144-C1149).  [PMID:23057639]
64. Suryakant K Niture,Anil K Jaiswal.  (2013-01-01)  Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance..  Free radical biology & medicine,  57  (119-131).  [PMID:23275004]
65. Rachel C Harbeitner,Mark E Hahn,Alicia R Timme-Laragy.  (2013-01-19)  Differential sensitivity to pro-oxidant exposure in two populations of killifish (Fundulus heteroclitus)..  Ecotoxicology (London, England),  22  ((2)): (387-401).  [PMID:23329125]
66. Xin-Yu Lu,Han-dong Wang,Jian-Guo Xu,Ke Ding,Tao Li.  (2014-01-07)  Pretreatment with tert-butylhydroquinone attenuates cerebral oxidative stress in mice after traumatic brain injury..  The Journal of surgical research,  188  ((1)): (206-212).  [PMID:24387843]
67. Xueqian Wang,Christopher R Campos,John C Peart,Lindsay K Smith,Jessica L Boni,Ronald E Cannon,David S Miller.  (2014-06-21)  Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  34  ((25)): (8585-8593).  [PMID:24948812]
68. Xuefen Xu,Yi Zhang,Wei Li,Hanchi Miao,Haiwei Zhang,Yuxin Zhou,Zhiyu Li,Qidong You,Li Zhao,Qinglong Guo.  (2014-09-30)  Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway..  Biochemical pharmacology,  92  ((2)): (220-234).  [PMID:25264278]
69. Marialucia Gallorini,Christine Petzel,Carola Bolay,Karl-Anton Hiller,Amelia Cataldi,Wolfgang Buchalla,Stephanie Krifka,Helmut Schweikl.  (2015-05-03)  Activation of the Nrf2-regulated antioxidant cell response inhibits HEMA-induced oxidative stress and supports cell viability..  Biomaterials,  56  (114-128).  [PMID:25934285]
70. E W Cloer,P F Siesser,E M Cousins,D Goldfarb,D D Mowrey,J S Harrison,S J Weir,N V Dokholyan,M B Major.  (2018-08-22)  p62-dependent phase separation of patient-derived KEAP1 mutations and NRF2..  Molecular and cellular biology,      [PMID:30126895]
71. Lu Qiu,Meng Wang,Shaofan Hu,Xufang Ru,Yonggang Ren,Zhengwen Zhang,Siwang Yu,Yiguo Zhang.  (2018-12-20)  Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor..  Cancers,  10  ((12)):   [PMID:30562963]
72. Tatsuya Ogawa,Yosuke Ishitsuka,Yoshiyuki Nakamura,Noriko Kubota,Akimasa Saito,Yasuhiro Fujisawa,Rei Watanabe,Naoko Okiyama,Yasushi Suga,Dennis R Roop,Manabu Fujimoto.  (2020-07-22)  NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy..  Journal of immunology (Baltimore, Md. : 1950),  205  ((4)): (907-914).  [PMID:32690656]

Solution Calculators