Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites. Tetracycline-induced CK2 expression significantly increases the non–small cell lung cancer (NSCLC) invasion in cells expressing BRMS1 wild-type, but not the S30A mutant.
Applications：
Tetracycline is a compound that has been shown to induce apoptosis in various cells. Tetracycline was a useful compound to study drug resistance of pathogens of infections in patients with severe liver disease.
1.Hamasuna R, Jensen JS, Osada Y. (2009) Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR.. Antimicrob Agents Chemother, 53 (11):(4938-9). [PMID:19738019]
2.Zhipeng Zhang, Yao Tian, Pengcheng Huang, Fang-Ying Wu. (2019) Using target-specific aptamers to enhance the peroxidase-like activity of gold nanoclusters for colorimetric detection of tetracycline antibiotics. talanta, 208 (11):(120342). [PMID:]
3.Zhipeng Zhang, Ying Liu, Pengcheng Huang, Fang-Ying Wu, Lihua Ma. (2021) Polydopamine molecularly imprinted polymer coated on a biomimetic iron-based metal–organic framework for highly selective fluorescence detection of metronidazole. talanta, 232 (11):(122411). [PMID:]
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