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Tetracycline - 10mM in DMSO, high purity , CAS No.60-54-8(DMSO)
Basic Description Synonyms tetracycline|60-54-8|Deschlorobiomycin|Tetracyclinum|Achromycin|Tetracyclin|Sumycin|Abramycin|Tsiklomitsin|Cyclopar|Ambramycin|Liquamycin|Panmycin|Tetracyn|Tetrazyklin|Achromycin V|Hostacyclin|Omegamycin|Tetradecin|Tetraverine|Tsiklomistsin|Vetacyclinum|T Specifications & Purity 10mM in DMSO Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description Tetracycline is used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, Jurkat T lymphocyte cells and in cultured monocytes and macrophages. Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis.
Names and Identifiers IUPAC Name (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide INCHI InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1 InChi Key NWXMGUDVXFXRIG-WESIUVDSSA-N Canonical SMILES CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O Isomeric SMILES C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O PubChem CID 54675776 Molecular Weight 444.44
Chemical and Physical Properties Solubility Soluble in 1M HCl with heating;≥74.9 mg/mL in DMSO; insoluble in EtOH Sensitivity Hygroscopic,Light sensitive. Melt Point(°C) 172-174℃
References 1. Zhipeng Zhang, Ying Liu, Pengcheng Huang, Fang-Ying Wu, Lihua Ma. (2021) Polydopamine molecularly imprinted polymer coated on a biomimetic iron-based metal–organic framework for highly selective fluorescence detection of metronidazole. talanta, 232 (11): (122411). [PMID: ]
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