Tetracycline - 10mM in DMSO, high purity , CAS No.60-54-8(DMSO)

Item Number
T580568
Grouped product items
SKUSizeAvailabilityPrice Qty
T580568-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$72.90

Basic Description

Synonymstetracycline | 60-54-8 | Deschlorobiomycin | Tetracyclinum | Achromycin | Tetracyclin | Sumycin | Abramycin | Tsiklomitsin | Cyclopar | Ambramycin | Liquamycin | Panmycin | Tetracyn | Tetrazyklin | Achromycin V | Hostacyclin | Omegamycin | Tetradecin | Tetraverine | Tsiklomistsin | Vetacyclinum | T
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsTetracycline inhibits bacterial protein synthesis elongation at the level of aminoacyl-tRNA binding to the 30S ribosome. Tetracycline passively diffuses through porin channels in the bacterial cell membrane. It also binds to the bacterial 50S ribosomal su
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

Tetracycline is used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, Jurkat T lymphocyte cells and in cultured monocytes and macrophages.
Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis.

Names and Identifiers

IUPAC Name (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
INCHI InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1
InChi Key NWXMGUDVXFXRIG-WESIUVDSSA-N
Canonical SMILES CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
Isomeric SMILES C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
PubChem CID 54675776
Molecular Weight 444.44

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in 1M HCl with heating;≥74.9 mg/mL in DMSO; insoluble in EtOH
SensitivityHygroscopic,Light sensitive.
Melt Point(°C)172-174℃

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Citations of This Product

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2. Li Wang, Ya Jiao, Kaixin Zhao, Guohao Cheng, Lin Liu, Yongli Liu, Guifen Zhu.  (2024)  A novel carbonized polymer dots-based molecularly imprinted polymer with superior affinity and selectivity for oxytetracycline removal.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  656  (22): (332).  [PMID:37995403] [10.1016/j.jcis.2023.11.115]
3. Yanqiu Zhang, Yang Lu, Minrui Sun, Dechang Zeng.  (2024)  A Multi-Functional Fluorescence Sensing Platform Based on a Defective UiO-66 for Tetracycline and Moxifloxacin.  Water,  16  (1): (145).  [PMID:] [10.3390/w16010145]
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Solution Calculators