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Tetraethylenepentamine pentahydrochloride - 98%, high purity , CAS No.4961-41-5

  • ≥98%
Item Number
T432755
Grouped product items
SKUSizeAvailabilityPrice Qty
T432755-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$112.90
T432755-50g
50g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$628.90
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Basic Description

SynonymsTetraethylenepentamine pentahydrochloride|4961-41-5|TETRAETHYLENEPENTAMINEPENTAHYDROCHLORIDE|Tetraethylenepentamine (pentahydrochloride)|N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine;pentahydrochloride|Tetraethylenepentamine 5HCl|CHEMBL4
Specifications & Purity98%
Product Description

Tetraethylenepentamine pentahydrochloride (TETRAEN) is an amine salt having five amine groups, which have catalytic roles in various reactions. Tetraethylenepentamine pentahydrochloride is reported as copper-chelating agent. Regeneration of pancreatic endocrine cells in rats maintained on a copper-deficient diet containing tetraethylenepentamine pentahydrochloride has been reported. It is a high affinity copper and zinc chelator.


Application

Tetraethylenepentamine pentahydrochloride (TETRAEN) has been employed as polyamine catalyst for the bisulfite reaction of cytosine. Tetraethylenepentamine pentahydrochloride is suitable for in vitro translation, using promega′s flexi rabbit reticulocyte lysate kit.

Names and Identifiers

IUPAC Name N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine;pentahydrochloride
INCHI InChI=1S/C8H23N5.5ClH/c9-1-3-11-5-7-13-8-6-12-4-2-10;;;;;/h11-13H,1-10H2;5*1H
InChi Key VGICAQBLDJAGSJ-UHFFFAOYSA-N
Canonical SMILES C(CNCCNCCNCCN)N.Cl.Cl.Cl.Cl.Cl
Isomeric SMILES C(CNCCNCCNCCN)N.Cl.Cl.Cl.Cl.Cl
WGK Germany 3
PubChem CID 10309252
Molecular Weight 371.61

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Melt Point(°C)280° C (dec.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RIDADR NONHforallmodesoftransport

Related Documents

 SDS

 Specification Sheet

References

1. Cami K Bruns,Ron R Kopito.  (2007-01-27)  Impaired post-translational folding of familial ALS-linked Cu, Zn superoxide dismutase mutants..  The EMBO journal,  26  ((3)): (855-866).  [PMID:17255946]
2. Ben J Gu,James A Duce,Valentina A Valova,Bruce Wong,Ashley I Bush,Steven Petrou,James S Wiley.  (2012-03-31)  P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in cerebrospinal fluid..  The Journal of biological chemistry,  287  ((21)): (17318-17330).  [PMID:22461619]
3. Yarui Diao,Xing Guo,Lei Jiang,Gang Wang,Chao Zhang,Jun Wan,Yan Jin,Zhenguo Wu.  (2013-11-20)  miR-203, a tumor suppressor frequently down-regulated by promoter hypermethylation in rhabdomyosarcoma..  The Journal of biological chemistry,  289  ((1)): (529-539).  [PMID:24247238]
4. Florida Voli,Emanuele Valli,Luigi Lerra,Kathleen Kimpton,Federica Saletta,Federico M Giorgi,Daniele Mercatelli,Jourdin R C Rouaen,Sylvie Shen,Jayne E Murray,Aria Ahmed-Cox,Giuseppe Cirillo,Chelsea Mayoh,Paul A Beavis,Michelle Haber,Joseph A Trapani,Maria Kavallaris,Orazio Vittorio.  (2020-08-21)  Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion..  Cancer research,  80  ((19)): (4129-4144).  [PMID:32816860]
5. I H Al-Abdullah,T Ayala,D Panigrahi,A M Kumar,M S Kumar.  (2000-07-06)  Neogenesis of pancreatic endocrine cells in copper-deprived rat models..  Pancreas,  21  ((1)): (63-68).  [PMID:10881934]
6. Franziska Haag,Lucky Ahmed,Krystle Reiss,Eric Block,Victor S Batista,Dietmar Krautwurst.  (2019-08-23)  Copper-mediated thiol potentiation and mutagenesis-guided modeling suggest a highly conserved copper-binding motif in human OR2M3..  Cellular and molecular life sciences : CMLS,  77  ((11)): (2157-2179).  [PMID:31435697]
7. Thien Van Truong,Mihir Ghosh,Ramprasad Misra,Olga Krichevski,Ellen Wachtel,Noga Friedman,Mordechai Sheves,Guy Patchornik.  (2020-05-21)  Conjugation of native membranes via linear oligo-amines..  Colloids and surfaces. B, Biointerfaces,  193  (111101-111101).  [PMID:32434136]

Solution Calculators

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