Basic Description

Synonyms	AKOS009156489 \| NCGC00257565-01 \| Tetramethylsilane (TMS) \| Tetramethylsilane [UN2749] [Flammable liquid] \| Tetramethylsilane, >=99.0% (GC) \| EINECS 200-899-1 \| CT2050 \| TETRAMETHYLSILANE [MI] \| (CH3)4Si \| MFCD00008274 \| UN 2749 \| T0154 \| Silicon, tetram
Specifications & Purity	analytical standard, ACS, for NMR spectroscopy
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	ACS, analytical standard
Product Description	Tetramethylsilane has been recommended by the International Union of Pure and Applied Chemistry (IUPAC) as a universal reference for all nuclides. It is commonly used as a reference standard in nuclear magnetic resonance (NMR) for measuring proton chemical shifts and the temperature dependence of the 1 H chemical shift of TMS in solvents such as chloroform, methanol, and dimethylsulfoxide is studied. Application Tetramethylsilane may be used as an internal standard for the quantitative analysis of medicinal plant extracts and herbal products using the quantitative NMR (qNMR) method. It may also be used as an internal standard to investigate peroxide-based chemical systems for the crosslinking reactions carried on isotactic polypropylene using FT-IR spectrometry and proton nuclear magnetic resonance ( 1 H NMR) techniques.

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 integrase (9041 Activities)

Discover Target: pol

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	tetramethylsilane
INCHI	InChI=1S/C4H12Si/c1-5(2,3)4/h1-4H3
InChi Key	CZDYPVPMEAXLPK-UHFFFAOYSA-N
Canonical SMILES	C[Si](C)(C)C
Isomeric SMILES	C[Si](C)(C)C
WGK Germany	3
PubChem CID	6396
UN Number	2749
Packing Group	I
Molecular Weight	88.22
Beilstein	1696908

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Refractive Index	1.3585
Flash Point(°F)	-16.6 °F
Flash Point(°C)	-27 °C
Boil Point(°C)	26-28°C
Melt Point(°C)	−99 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS02
Signal	Danger
Hazard Statements	H224:Extremely flammable liquid and vapor
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge.
WGK Germany	3
Class	3
Merck Index	9229

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Xiong Zheng, Qiang Shi, Xuzhen Zhang, Wenjian Huang, Zhou Zhang, Bona Ding. (2023) The role and mechanism of temporary blocked isocyanate at interface between polyethylene terephthalate high-strength fibers and activation oil. JOURNAL OF APPLIED POLYMER SCIENCE, (e54992). [PMID:]
2. Qi Zhang, Jian Zhang, Qingwei Ping, Zhihui Sui, Xiangyu Cao, Tianyuan Xiao. (2024) A novel curcumin-based bilayer indicator film for freshness evaluation of shrimp with excellent mechanical properties and moisture resistance. PROGRESS IN ORGANIC COATINGS, 186 (108040). [PMID:25173926]
3. Zhiyong Xue, Juan Liu, Qing Li, Yuanyuan Yao, Yalin Yang, Chao Ran, Zhen Zhang, Zhigang Zhou. (2023) Synthesis of lipoic acid ferulate and evaluation of its ability to preserve fish oil from oxidation during accelerated storage. Food Chemistry-X, 19 (100802). [PMID:37780313]
4. He Wang, Qin Yao, Yanjing Guo, Qian Zhang, Zhongchang Wang, Reto Jörg Strasser, Bernal E. Valverde, Shiguo Chen, Sheng Qiang, Hazem M. Kalaji. (2022) Structure-based ligand design and discovery of novel tenuazonic acid derivatives with high herbicidal activity. Journal of Advanced Research, 40 (29). [PMID:36100332]
5. Yu Xueyi, Fang Zeming, Qin Yijing, Lu Dong, Liu Qianfa, Luo Li, Lin Zhiyong, Wang Ke. (2021) FTIR and NMR characterization of thermosetting methyl methacrylate terminated poly(2,6-dimethyl-1,4-phenylene oxide)—triallyl isocyanurate copolymer. JOURNAL OF POLYMER RESEARCH, 28 (7): (1-11). [PMID:]
6. Yuan Yang, Yao Wang, Xiaoling Hou, Yao Lin, Lu Yang, Xiandeng Hou, Chengbin Zheng. (2020) Can low-temperature point discharge Be used as atomic emission source for sensitive determination of cyclic volatile methylsiloxanes?. ANALYTICA CHIMICA ACTA, 1124 (121). [PMID:32534664]
7. Shijun Wang, Xiaorong Yuan, Hao Qian, Na Li, Junru Wang. (2020) Design, Synthesis, and Biological Evaluation of Two Series of Novel A-Ring Fused Steroidal Pyrazines as Potential Anticancer Agents. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21 (5): (1665). [PMID:32121303]

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Tetramethylsilane - analytical standard, for NMR spectroscopy, ACS reagent, high purity , CAS No.75-76-3