TH 1217 - ≥98%(HPLC), high purity , CAS No.1862212-48-3

Item Number

T288726

Grouped product items
SKU	Size	Availability	Price
T288726-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$157.90
T288726-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$256.90
T288726-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$513.90
T288726-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$820.90

Potent dCTP pyrophosphatase 1 inhibitor

Basic Description

Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Product description： TH1217 (ZINC1775962367) is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19.

InChi Key

HWFRCQHNILGMLL-UHFFFAOYSA-N

Canonical SMILES

CC1=NC2=C([N+]([O-])=O)C(Cl)=C(C=C2N1CC3=CC=C([B-]45OC(C[N+](CC(O5)=O)4C)=O)C=C3)Cl

PubChem CID

Molecular Weight

491.09

Certificates

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4 results found

Lot Number	Certificate Type	Date	Item
D2310053	Certificate of Analysis	Feb 22, 2023	T288726
D2310063	Certificate of Analysis	Feb 22, 2023	T288726
D2310064	Certificate of Analysis	Feb 22, 2023	T288726
D2310085	Certificate of Analysis	Feb 22, 2023	T288726

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Basic Description