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Thalidomide-Acid - 98%, high purity , CAS No.1061605-21-7

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Thalidomide-Acid - 98%, high purity , CAS No.1061605-21-7

≥98%

CAS#: 1061605-21-7
Formula: C₁₅H₁₂N₂O₇
Molecular Weight: 332.26
PubChem CID: 25015436

Item Number

T595105

Grouped product items
SKU	Size	Availability	Price
T595105-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$195.90
T595105-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$325.90
T595105-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$484.90

Thalidomide-Acid

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PROTAC Linkers

Basic Description

Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Thalidomide-Acid is a derivative of Thalidomide. It is commonly used as a precursor to PROTAC that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with a carboxylic acid functional handle at a position known not to significantly affect binding to cereblon, for ready conjugation to a linker/target protein ligand.

Associated Targets(Human)

HEK293 82097 Activities

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cereblon/Bromodomain-containing protein 4 275 Activities

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Names and Identifiers

IUPAC Name	2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetic acid
INCHI	InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21)
InChi Key	ZVWIXIGBWIEDFO-UHFFFAOYSA-N
Canonical SMILES	C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)O
Isomeric SMILES	C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)O
PubChem CID	25015436
Molecular Weight	332.26

Certificates

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Chemical and Physical Properties

Solubility	Solubility in DCM

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FAQs and Articles

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Targeted protein degradation technology: proprietary drugs are not difficult, drug resistance is no longer

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