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Thalidomide-PEG3-COOH - 98%, high purity , CAS No.T658943

  • ≥98%
  • Formula:   C20H22N2O9
  • Molecular Weight:  434.4
Item Number
T658943
Grouped product items
SKUSizeAvailabilityPrice Qty
T658943-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$390.90
T658943-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$620.90
T658943-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,000.90

Basic Description

Specifications & Purity98%
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Product Description

Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Appearance:Solid

IC50& Target:Cereblon

In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE

Biological Activity:Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Names and Identifiers

Canonical SMILES O=C1N(C2C(NC(CC2)=O)=O)C(C3=CC=C(OCCOCCOCCC(O)=O)C=C31)=O
Molecular Weight 434.4

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 250 mg/mL (575.51 mM; Need ultrasonic)

Related Documents

Solution Calculators