Grouped product items

SKU

Size

Availability

Price

Qty

T100896-250mg

250mg

Available within 4-8 weeks(?)

$16.90

T100896-1g

Available within 4-8 weeks(?)

$53.90

T100896-5g

Available within 4-8 weeks(?)

$243.90

T100896-25g

25g

Available within 4-8 weeks(?)

$1,093.90

T100896-100g

100g

Available within 4-8 weeks(?)

$3,936.90

Basic Description

Synonyms	Thiazolyl blue\|298-93-1\|Thiazolyl blue tetrazolium bromide\|MTT\|MMT Tetrazolium\|Methylthiazoletetrazolium\|2348-71-2\|Thiazolyl Blue Monotetrazolium\|3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide\|3-(4,5-Dimethylthiazolyl)-2,5-diphenyltetrazoliu
Specifications & Purity	98%
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Product Description	Thiazolyl Blue is a membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT Formazan). Spectrophotometric measurement of MTT Formazan at 540 or 570 nm allows quantitation of cell viability. Thiazolyl Blue is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. Thiazolyl Blue is also an electron acceptor used for studying NADP-dependent dehydrogenases. A membrane-permeable dye reduced by mitochondrial enzymes

Names and Identifiers

IUPAC Name	2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide
INCHI	InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChi Key	AZKSAVLVSZKNRD-UHFFFAOYSA-M
Canonical SMILES	CC1=C(SC(=N1)[N+]2=NC(=NN2C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]
Isomeric SMILES	CC1=C(SC(=N1)[N+]2=NC(=NN2C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]
WGK Germany	3
RTECS	XF8060000
Alternate CAS	2348-71-2
PubChem CID	64965
Molecular Weight	414.32
Beilstein	4081397
Reaxy-Rn	3825277

Certificates

Certificate of Analysis(COA)

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9 results found

Lot Number	Certificate Type	Date	Item
K2329089	Certificate of Analysis	Dec 06, 2023	T100896
K2329090	Certificate of Analysis	Dec 06, 2023	T100896
K2329091	Certificate of Analysis	Dec 06, 2023	T100896
K2329088	Certificate of Analysis	Dec 06, 2023	T100896
E2305096	Certificate of Analysis	Mar 15, 2023	T100896
E2305097	Certificate of Analysis	Mar 15, 2023	T100896
E2305099	Certificate of Analysis	Mar 15, 2023	T100896
E2305108	Certificate of Analysis	Mar 15, 2023	T100896
E2305111	Certificate of Analysis	Mar 15, 2023	T100896

Chemical and Physical Properties

Solubility	Soluble in water (20 mg/ml), ethanol (20 mg/ml), 2-methoxyethanol (20 mg/ml), buffered salt solutions (5 mg/ml), culture media (5 mg/ml), and PBS.
Sensitivity	Light & Moisture & Air sensitive
Melt Point(°C)	195°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H341:Suspected of causing genetic defects
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	XF8060000
Reaxy-Rn	3825277

References

1. Lesslich HM et al.. (2022) Adjusting the neuron to astrocyte ratio with cytostatics in hippocampal cell cultures from postnatal rats: A comparison of cytarabino furanoside (AraC) and 5-fluoro-2'-deoxyuridine (FUdR).. PLoS One, 17 (3): (e0265084). [PMID:35263366]
2. Fardoun M et al.. (2019) 7-O-methylpunctatin, a Novel Homoisoflavonoid, Inhibits Phenotypic Switch of Human Arteriolar Smooth Muscle Cells.. Biomolecules, 9 (11): [PMID:31717401]
3. Kim H & Jaffrey SR. (2019) A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization.. Cell Chem Biol, 26 (12): (1725-1731.e6). [PMID:31631009]
4. Poh HX et al.. (2022) Alternative splicing of METTL3 explains apparently METTL3-independent m6A modifications in mRNA.. PLoS Biol, 20 (7): (e3001683). [PMID:35853000]
5. Benadiba M et al.. (2018) Bioaccessibility of Shore Magic® collagen, a low-molecular-weight collagen supplement, in different in\xa0vitro barrier models.. Heliyon, 4 (9): (e00821). [PMID:30272033]
6. Parigiani MA et al.. (2020) Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression.. Cancers (Basel), 12 (8): [PMID:32707827]
7. Cheng CY et al.. (2021) Epigallocatechin-3-Gallate-Loaded Liposomes Favor Anti-Inflammation of Microglia Cells and Promote Neuroprotection.. Int J Mol Sci, 22 (6): [PMID:33809762]
8. Serruya R & Maor Y. (2021) Hair growth-promotion effects at the cellular level and antioxidant activity of the plant-based extract Phyllotex™.. Heliyon, 7 (9): (e07888). [PMID:34522800]
9. Varanda AS et al.. (2020) Human cells adapt to translational errors by modulating protein synthesis rate and protein turnover.. RNA Biol, 17 (135-149). [PMID:31570039]
10. Schröder SK et al.. (2022) Lipocalin-2 (LCN2) Deficiency Leads to Cellular Changes in Highly Metastatic Human Prostate Cancer Cell Line PC-3.. Cells, 11 (2): [PMID:35053376]
11. Tang XJ et al.. (2016) Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells.. Int J Nanomedicine, 11 (4991-5002). [PMID:27757032]
12. Ablinger M et al.. (2021) Personalized Development of Antisense Oligonucleotides for Exon Skipping Restores Type XVII Collagen Expression in Junctional Epidermolysis Bullosa.. Int J Mol Sci, 22 (7): [PMID:33805154]
13. Hasemann G et al.. (2021) Refractory Metal Coated Alumina Foams as Support Material for Stem Cell and Fibroblasts Cultivation.. Materials (Basel), 14 (11): [PMID:34070481]
14. Huang J et al.. (2017) Role of gambogic acid and NaI(131) in A549/DDP cells.. Oncol Lett, 13 (37-44). [PMID:28123519]
15. Chang LC et al.. (2020) The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study.. Biomedicines, 8 (11): [PMID:33266505]
16. Jones O et al.. (2021) The synergistic effect of Canady Helios cold atmospheric plasma and a FOLFIRINOX regimen for the treatment of cholangiocarcinoma in vitro.. Sci Rep, 11 (8967). [PMID:33903679]

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Thiazolyl Blue Tetrazolium Bromide - 98%, high purity , CAS No.298-93-1

Basic Description

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
T100896-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$16.90
T100896-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$53.90
T100896-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$243.90
T100896-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,093.90
T100896-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$3,936.90