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Thiosildenafil - 98%, high purity , CAS No.479073-79-5
Basic Description
Synonyms | Sulfosildenafil | 5-(2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl)-1-methyl-3-propyl-4H-pyrazolo(4,3-d)pyrimidine-7-thione | PIPERAZINE, 1-((3-(4,7-DIHYDRO-1-METHYL-3-PROPYL-7-THIOXO-1H-PYRAZOLO(4,3-D)PYRIMIDIN-5-YL)-4-ETHOXYPHENYL)SULFONYL)-4-METHYL |
Specifications & Purity | ≥98% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Product Description | Thiosildenafil is a novel pyrazolopyrimidinethione analog of sildenafil which acts as a PDE5A inhibitor. |
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Names and Identifiers
IUPAC Name | 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione |
INCHI | InChI=1S/C22H30N6O3S2/c1-5-7-17-19-20(27(4)25-17)22(32)24-21(23-19)16-14-15(8-9-18(16)31-6-2)33(29,30)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,32) |
InChi Key | LJUBVCQVNMLSTQ-UHFFFAOYSA-N |
Canonical SMILES | CCCC1=NN(C2=C1NC(=NC2=S)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C |
Isomeric SMILES | CCCC1=NN(C2=C1NC(=NC2=S)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C |
PubChem CID | 10228242 |
Molecular Weight | 490.64 |
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Chemical and Physical Properties
Solubility | Soluble in chloroform, methanol, DMSO (~5 mg/ml), DMF (~16 mg/ml), and 1: 3 solution of DMF: PBS (pH 7.2) (~0.25 mg/ml). |
Refractive Index | n20D1.68 (Predicted) |
Boil Point(°C) | 676.06° C at 760 mmHg (Predicted) |
Melt Point(°C) | 172-174° C |
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