| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| T343461-5mg | 5mg | In stock | $399.90 |
a metabolite of Klebsiella oxytoca, proven to be linked to antibiotic-associated Hemorrhagic Colitis.
| Synonyms | Epitilivalline | (11s,11as)-9-hydroxy-11-(1h-indol-3-yl)-1,2,3,10,11,11a-hexahydro-5h-pyrrolo[2,1-c][1,4]benzodiazepin-5-one | (6S,6aS)-4-hydroxy-6-(1H-indol-3-yl)-5,6,6a,7,8,9-hexahydropyrrolo[2,1-c][1,4]benzodiazepin-11-one |
|---|---|
| Specifications & Purity | ≥97% |
| Storage Temp | Store at -20°C,Argon charged |
| Shipped In | Ice chest + Ice pads |
| Product Description | Tilivalline is a metabolite of Klebsiella oxytoca. Tilivalline is known to be cytotoxic. The metabolization of Tilivalline is propven to be linked to antibiotic-associated Hemorrhagic Colitis. The derivatives of Tilivalline were able to be synthesized efficiently and stereoselectively from diphenyl phosphorazidate, the 2-oxazoline, L-proline derivatives 5, and Indole in a Mannich-type intramolecular cyclization reaction. |
| IUPAC Name | (6S,6aS)-4-hydroxy-6-(1H-indol-3-yl)-5,6,6a,7,8,9-hexahydropyrrolo[2,1-c][1,4]benzodiazepin-11-one |
|---|---|
| INCHI | InChI=1S/C20H19N3O2/c24-17-9-3-6-13-19(17)22-18(16-8-4-10-23(16)20(13)25)14-11-21-15-7-2-1-5-12(14)15/h1-3,5-7,9,11,16,18,21-22,24H,4,8,10H2/t16-,18-/m0/s1 |
| InChi Key | AJZNARCWDDMOPL-WMZOPIPTSA-N |
| Canonical SMILES | C1CC2C(NC3=C(C=CC=C3O)C(=O)N2C1)C4=CNC5=CC=CC=C54 |
| Isomeric SMILES | C1C[C@H]2[C@@H](NC3=C(C=CC=C3O)C(=O)N2C1)C4=CNC5=CC=CC=C54 |
| PubChem CID | 128363 |
| Molecular Weight | 333.38 |
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| Solubility | DMSO(Slightly), Methanol(Slightly, Sonicated,Heated) |
|---|
E2424085