| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| T407841-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $173.90 |
Carbonic Anhydrase I Selective Inhibitors
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Biochemical and Physiological Mechanisms | Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Information Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. Tioxolone is reported to possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics (e.g. hair shampoos and skin cleansers), due to claims for its oil-regulating and antibacterial properties. The three-dimensional framework of Tioxolone is further stabilized by π-π interactions between the oxathiolone and benzene rings in partially overlapping molecules. In vivo Tioxolone, a Benzoxathiol derivatives, has been used in the local therapy of psoriasis vulgaris and acne, and also reported to have anti-bacterial, anti-mycotic, and cytostatic properties. cell lines： Concentrations： Incubation Time： Powder Purity:≥98% |
| Ki Data | CAI, Ki: 91 nM |
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| Canonical SMILES | OC1=CC=C2SC(=O)OC2=C1 |
|---|---|
| Molecular Weight | 168.17 |
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| Solubility | Solubility (25°C) In vitro DMSO: 73 mg/mL (197.91 mM); Water: Insoluble; Ethanol: Insoluble; |
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