Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1).
In Vitro
In vitro transfection of tivanisiran was shown to produce a 50-60% decrease in TRPV1 mRNA levels . MCE has not independently confirmed the accuracy of these methods. They are for reference only.