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TL-895 - 10mM in DMSO, high purity , CAS No.1415823-49-2(DMSO)

  • 10mM in DMSO
Item Number
T655969
Grouped product items
SKUSizeAvailabilityPrice Qty
T655969-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$132.90
View related series
Btk Protein Tyrosine Kinase/RTK

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC 50 and a K i of 1.5 nM and 11.9 nM, respectively TL-895 is used be for JAKi-relapsed/refractory myelofibrosis, acute myeloid leukemia, COVID-19 and cancer research

IC50& Target:IC50: 1.5 nM,Ki: 11.9 nM (BTK)

Names and Identifiers

Canonical SMILES O=C(N1CCC(CNC2=NC=NC(N)=C2C3=CC=C(C=C3)OC4=CC=CC=C4)(CC1)F)C=C
Molecular Weight 447.50

Certificates

Certificate of Analysis(COA)

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Solution Calculators