TM 5275 sodium salt - ≥98%(HPLC), high purity , CAS No.1103926-82-4

  • ≥98%(HPLC)
Item Number
T287019
Grouped product items
SKUSizeAvailabilityPrice Qty
T287019-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$296.90
T287019-10mg
10mg
In stock
$420.90
T287019-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$718.90
T287019-50mg
50mg
In stock
$1,214.90
T287019-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,207.90
T287019-200mg
200mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$3,974.90

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

View related series
Metabolic Enzyme/Protease PAI-1

Basic Description

Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsPlasminogen activator inhibitor-1 (PAI-1) inhibitor. Orally bioavailable.TMS5275 is an orally available, potent and selective inhibitor of PAI-1 that delivers antithrombotic benefits devoid of bleeding effect in nonhuman primates.
Storage TempStore at 2-8°C
Shipped InWet ice

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name sodium;2-[[2-[2-(4-benzhydrylpiperazin-1-yl)-2-oxoethoxy]acetyl]amino]-5-chlorobenzoate
INCHI InChI=1S/C28H28ClN3O5.Na/c29-22-11-12-24(23(17-22)28(35)36)30-25(33)18-37-19-26(34)31-13-15-32(16-14-31)27(20-7-3-1-4-8-20)21-9-5-2-6-10-21;/h1-12,17,27H,13-16,18-19H2,(H,30,33)(H,35,36);/q;+1/p-1
InChi Key JSHSGBIWNPQCQZ-UHFFFAOYSA-M
Canonical SMILES C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)COCC(=O)NC4=C(C=C(C=C4)Cl)C(=O)[O-].[Na+]
Isomeric SMILES C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)COCC(=O)NC4=C(C=C(C=C4)Cl)C(=O)[O-].[Na+]
PubChem CID 53240409
Molecular Weight 543.97

Certificates

Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
D2307038Certificate of AnalysisMar 10, 2023 T287019
D2317039Certificate of AnalysisMar 10, 2023 T287019
D2317041Certificate of AnalysisMar 10, 2023 T287019
D2317082Certificate of AnalysisMar 10, 2023 T287019
D2317087Certificate of AnalysisMar 10, 2023 T287019
D2317092Certificate of AnalysisMar 10, 2023 T287019
D2317093Certificate of AnalysisMar 10, 2023 T287019
D2317102Certificate of AnalysisMar 10, 2023 T287019

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 54.4, Max Conc. mM: 100
SensitivityMoisture sensitive

Safety and Hazards(GHS)

RIDADR UN30779/PGIII

Related Documents

Solution Calculators