Toralizumab (anti-CD40L) is a humanized monoclonal antibody (mAb) against CD40L (CD154) comprised of human gamma 1 heavy chains and human kappa light chains. Toralizumab (anti-CD40L) binds specifically to human CD40L on T cells, thereby preventing CD40 signaling. Toralizumab (anti-CD40L), a immunosuppressive agent, has the potential for active systemic lupus erythematosus (SLE) research. Purity >95% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg
Product Properties
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
26.5 kDa (Light Chain) & 52.0 kDa (Heavy Chain), under reducing conditions; 197.3 kDa, under non-reducing conditions.
Purification Method
Protein A purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS
252662-47-8
Images
Toralizumab (anti-CD40L) (Ab183447) - ELISA Immobilized Recombinant Human CD40 Ligand protein (rp169583) at 1.0 μg/mL can bind Toralizumab (anti-CD40L) (Ab183447) with the EC50 of 44.75 ng/mL.
Toralizumab (anti-CD40L) (Ab183447) - SEC The purity of Toralizumab (anti-CD40L) (Ab183447) is more than 95% verified by HPLC.