Grouped product items

SKU

Size

Availability

Price

Qty

D106380-1g

In stock

$31.90

D106380-5g

In stock

$109.90

D106380-25g

25g

In stock

$359.90

D106380-100g

100g

In stock

$1,035.90

D106380-500g

500g

Available within 4-8 weeks(?)

$3,629.90

Basic Description

Synonyms	Dehydroepiandrosterone\|DHEA\|PRASTERONE\|53-43-0\|Dehydroisoandrosterone\|Androstenolone\|trans-Dehydroandrosterone\|Psicosterone\|Diandrone\|Diandron\|3beta-hydroxyandrost-5-en-17-one\|Prestara\|17-Hormoforin\|17-Chetovis\|Andrestenol\|Intrarosa\|5-Dehydroepiandrostero
Specifications & Purity	Moligand™, ≥99%
Biochemical and Physiological Mechanisms	GABAA 受体的负调节剂。肾上腺分泌的类固醇，具有雌激素和雄激素特性。它转化为 5-雄烯二醇（一种有效的雌激素）可增强雌激素敏感性乳腺肿瘤的生长和存活率。在高浓度但生理有效的条件下，DHEA 抑制嗜铬细胞祖细胞的增殖并诱导多巴胺能分化。脱氢雄激素（DHEA）是 GABAA 受体的负调节剂。它是肾上腺分泌的类固醇，具有雌激素和雄激素特性。脱氢表雄酮（DHEA）转化为 5-雄烯二醇（一种有效的雌激素）可增强雌激素敏感性乳腺肿瘤的生长和存活率。
Shipped In	Normal
Grade	Moligand™

Product Properties

ALogP	3.2

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Discover Target: EHMT2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CBX1 Tbio Chromobox protein homolog 1 0 Activities

Discover Target: CBX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSD17B7 Tchem 3-keto-steroid reductase 0 Activities

Discover Target: HSD17B7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP46A1 Tchem Cholesterol 24-hydroxylase 0 Activities

Discover Target: CYP46A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SULT2A1 Tbio Bile salt sulfotransferase 0 Activities

Discover Target: SULT2A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SULT2B1 Tbio Sulfotransferase family cytosolic 2B member 1 0 Activities

Discover Target: SULT2B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SULT1E1 Tchem Estrogen sulfotransferase 0 Activities

Discover Target: SULT1E1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

Discover Target: USP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D3 receptor 0 Activities

Discover Target: VDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Discover Target: KMT2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 0 Activities

Discover Target: UGT2B15

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SNCA Tchem Alpha-synuclein 0 Activities

Discover Target: SNCA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A4 Tbio UDP-glucuronosyltransferase 1-4 0 Activities

Discover Target: UGT1A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SHBG Tchem Sex hormone-binding globulin 1 Activities

Discover Target: SHBG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 0 Activities

Discover Target: PMP22

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LMNA Tbio Prelamin-A/C 0 Activities

Discover Target: LMNA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1I3 Tchem Nuclear receptor subfamily 1 group I member 3 0 Activities

Discover Target: NR1I3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SERPINA6 Tchem Corticosteroid-binding globulin 0 Activities

Discover Target: SERPINA6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GUSB Tchem Beta-glucuronidase 0 Activities

Discover Target: GUSB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Discover Target: APEX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Discover Target: MAOA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TARDBP Tchem TAR DNA-binding protein 43 0 Activities

Discover Target: TARDBP

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT2B17 Tbio UDP-glucuronosyltransferase 2B17 0 Activities

Discover Target: UGT2B17

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GPBAR1 Tchem G-protein coupled bile acid receptor 1 0 Activities

Discover Target: GPBAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

G6PD Tchem Glucose-6-phosphate 1-dehydrogenase 0 Activities

Discover Target: G6PD

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NPC1L1 Tclin NPC1-like intracellular cholesterol transporter 1 0 Activities

Discover Target: NPC1L1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
INCHI	InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
InChi Key	FMGSKLZLMKYGDP-USOAJAOKSA-N
Canonical SMILES	CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C
Isomeric SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)O)C
WGK Germany	2
RTECS	BV8396000
PubChem CID	5881
Molecular Weight	288.43
Beilstein	2058110

Database links

PubChem CID	5881
DrugBank Ligand	DB01708
CAS Registry No.	53-43-0
Wikipedia	Dehydroepiandrosterone
ChEMBL Ligand	CHEMBL90593
BindingDB Ligand	50223368
ChEBI	CHEBI:28689
NURSA Ligand	10.1621/PNXJ6CHX7S
RCSB PDB Ligand	AND
DrugCentral Ligand	795

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

25 results found

Lot Number	Certificate Type	Date	Item
F2421219	Certificate of Analysis	Jun 06, 2024	D106380
F2421218	Certificate of Analysis	Jun 06, 2024	D106380
F2421217	Certificate of Analysis	Jun 06, 2024	D106380
F2421215	Certificate of Analysis	Jun 06, 2024	D106380
F2421216	Certificate of Analysis	Jun 06, 2024	D106380
E2324271	Certificate of Analysis	Sep 16, 2023	D106380
A2403044	Certificate of Analysis	Jul 31, 2023	D106380
H2316371	Certificate of Analysis	Jul 31, 2023	D106380
H2316370	Certificate of Analysis	Jul 31, 2023	D106380
H2316369	Certificate of Analysis	Jul 31, 2023	D106380
H2316368	Certificate of Analysis	Jul 31, 2023	D106380
H2316367	Certificate of Analysis	Jul 31, 2023	D106380
F2315991	Certificate of Analysis	Jun 29, 2023	D106380
A2220037	Certificate of Analysis	Feb 17, 2022	D106380
F2315993	Certificate of Analysis	Feb 14, 2022	D106380
L2216807	Certificate of Analysis	Feb 14, 2022	D106380
F2315996	Certificate of Analysis	Feb 14, 2022	D106380
E2207029	Certificate of Analysis	Feb 14, 2022	D106380
E2207024	Certificate of Analysis	Feb 14, 2022	D106380
E2207023	Certificate of Analysis	Feb 14, 2022	D106380
E2207019	Certificate of Analysis	Feb 14, 2022	D106380
E2207018	Certificate of Analysis	Feb 14, 2022	D106380
A2221040	Certificate of Analysis	Jan 27, 2022	D106380
E1618016	Certificate of Analysis	Jan 24, 2022	D106380
C1829062	Certificate of Analysis	Jan 24, 2022	D106380

Chemical and Physical Properties

Melt Point(°C)	146-151°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS09, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects H360:May damage fertility or the unborn child H362:May cause harm to breast-fed children
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	2
RTECS	BV8396000

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trans-Dehydroandrosterone - 99%, high purity , CAS No.53-43-0

Basic Description

Product Properties

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

CBX1 Tbio Chromobox protein homolog 1 0 Activities

HSD17B7 Tchem 3-keto-steroid reductase 0 Activities

CYP46A1 Tchem Cholesterol 24-hydroxylase 0 Activities

SULT2A1 Tbio Bile salt sulfotransferase 0 Activities

SULT2B1 Tbio Sulfotransferase family cytosolic 2B member 1 0 Activities

SULT1E1 Tchem Estrogen sulfotransferase 0 Activities

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

VDR Tclin Vitamin D3 receptor 0 Activities

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 0 Activities

SNCA Tchem Alpha-synuclein 0 Activities

UGT1A4 Tbio UDP-glucuronosyltransferase 1-4 0 Activities

SHBG Tchem Sex hormone-binding globulin 1 Activities

PMP22 Tbio Peripheral myelin protein 22 0 Activities

LMNA Tbio Prelamin-A/C 0 Activities

NR1I3 Tchem Nuclear receptor subfamily 1 group I member 3 0 Activities

SERPINA6 Tchem Corticosteroid-binding globulin 0 Activities

GUSB Tchem Beta-glucuronidase 0 Activities

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

TARDBP Tchem TAR DNA-binding protein 43 0 Activities

UGT2B17 Tbio UDP-glucuronosyltransferase 2B17 0 Activities

GPBAR1 Tchem G-protein coupled bile acid receptor 1 0 Activities

G6PD Tchem Glucose-6-phosphate 1-dehydrogenase 0 Activities

NPC1L1 Tclin NPC1-like intracellular cholesterol transporter 1 0 Activities

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

more

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Alternative Products

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