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TRAP-6 - 10mM in Water, high purity , CAS No.141136-83-6(Water)

  • 10mM in Water
Item Number
T655678
Grouped product items
SKUSizeAvailabilityPrice Qty
T655678-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$165.90

Basic Description

Specifications & Purity10mM in Water
Storage TempDesiccated,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor . TRAP-6 shows no activity at PAR4

In Vitro

TRAP-6 (0.01-10 μM) triggers calcium mobilization in Xenopus oocytes heterologously expressing PAR1. TRAP-6 (0.01-10 μM; 30 min) activates human platelets. TRAP-6 (100 μM) does not cause the platelets of rabbits or rats to change shape, aggregate, release granule contents, or form thromboxane. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

TRAP (1 mg/kg; i.v.) produces a biphasic response in blood pressure in inactin-anesthetized rats. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:PAR1

Names and Identifiers

Canonical SMILES CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CO)N
Molecular Weight 748.88

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