Grouped product items

SKU

Size

Availability

Price

Qty

T102692-100g

100g

In stock

$17.90

T102692-250g

250g

Available within 8-12 weeks(?)

$38.90

T102692-500g

500g

Available within 4-8 weeks(?)

$49.90

Basic Description

Synonyms	56375-79-2\|Tributylmethylammonium chloride\|n,n-dibutyl-n-methylbutan-1-aminium chloride\|Methyltributylammonium chloride\|methyl tributyl ammonium chloride\|1-Butanaminium, N,N-dibutyl-N-methyl-, chloride\|Aliquat 175\|tributyl(methyl)azanium;chloride\|AZ0B34ME
Specifications & Purity	75 wt. % in H2O
Storage Temp	Desiccated
Shipped In	Normal

Names and Identifiers

IUPAC Name	tributyl(methyl)azanium;chloride
INCHI	InChI=1S/C13H30N.ClH/c1-5-8-11-14(4,12-9-6-2)13-10-7-3;/h5-13H2,1-4H3;1H/q+1;/p-1
InChi Key	IPILPUZVTYHGIL-UHFFFAOYSA-M
Canonical SMILES	CCCC[N+](C)(CCCC)CCCC.[Cl-]
Isomeric SMILES	CCCC[N+](C)(CCCC)CCCC.[Cl-]
WGK Germany	3
PubChem CID	91822
Molecular Weight	235.84
Beilstein	6300212
Reaxy-Rn	6300212

Certificates

Certificate of Analysis(COA)

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9 results found

Lot Number	Certificate Type	Date	Item
H2415529	Certificate of Analysis	Aug 24, 2024	T102692
H2415530	Certificate of Analysis	Aug 24, 2024	T102692
H2415531	Certificate of Analysis	Aug 24, 2024	T102692
F2105211	Certificate of Analysis	Mar 21, 2024	T102692
F2105212	Certificate of Analysis	Mar 21, 2024	T102692
F2105289	Certificate of Analysis	Mar 21, 2024	T102692
F1508111	Certificate of Analysis	Jan 22, 2024	T102692
B2303947	Certificate of Analysis	Feb 07, 2023	T102692
B2209152	Certificate of Analysis	Feb 14, 2022	T102692

Chemical and Physical Properties

Sensitivity	Hygroscopic.

Safety and Hazards(GHS)

Pictogram(s)	GHS09, GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H413:May cause long lasting harmful effects to aquatic life H302:Harmful if swallowed H312:Harmful in contact with skin H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	6300212

References

1. H Steen,M Merema,D K Meijer. (1992-12-15) A multispecific uptake system for taurocholate, cardiac glycosides and cationic drugs in the liver.. Biochemical pharmacology, 44 ((12)): (2323-2331). [PMID:1472097]
2. H Steen,M Merema,D K Meijer. (1994-09-01) Effect of ethanol on hepatobiliary transport of cationic drugs. A study in the isolated perfused rat liver, rat hepatocytes and rat mitochondria.. Journal of hepatology, 21 ((3)): (308-314). [PMID:7836698]
3. H Steen,H Smit,A Nijholt,M Merema,D K Meijer. (1993-11-01) Modulators of the protein kinase C system influence biliary excretion of cationic drugs.. Hepatology (Baltimore, Md.), 18 ((5)): (1208-1215). [PMID:8225227]
4. H Steen,J G Maring,D K Meijer. (1993-02-24) Differential effects of metabolic inhibitors on cellular and mitochondrial uptake of organic cations in rat liver.. Biochemical pharmacology, 45 ((4)): (809-818). [PMID:8452555]
5. R H Moseley,H Smit,B G Van Solkema,W Wang,D K Meijer. (1996-02-01) Mechanisms for the hepatic uptake and biliary excretion of tributylmethylammonium: studies with rat liver plasma membrane vesicles.. The Journal of pharmacology and experimental therapeutics, 276 ((2)): (561-567). [PMID:8632322]
6. J W Smit,E Duin,H Steen,R Oosting,J Roggeveld,D K Meijer. (1998-03-21) Interactions between P-glycoprotein substrates and other cationic drugs at the hepatic excretory level.. British journal of pharmacology, 123 ((3)): (361-370). [PMID:9504375]
7. J W Smit,A H Schinkel,B Weert,D K Meijer. (1998-06-26) Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted.. British journal of pharmacology, 124 ((2)): (416-424). [PMID:9641561]
8. I S Song,S J Chung,C K Shim. (1999-05-05) Different activity of ATP dependent transport across the canalicular membrane for tributylmethylammonium and triethylmethylammonium as a potential mechanism of the preferential biliary excretion for tributylmethylammonium in the rat.. Pharmaceutical research, 16 ((4)): (540-544). [PMID:10227709]
9. Y H Han,S J Chung,C K Shim. (1999-07-27) Canalicular membrane transport is primarily responsible for the difference in hepatobiliary excretion of triethylmethylammonium and tributylmethylammonium in rats.. Drug metabolism and disposition: the biological fate of chemicals, 27 ((8)): (872-879). [PMID:10421613]
10. S S Hong,S J Chung,C K Shim. (2000-09-16) Functional impairment of sinusoidal membrane transport of organic cations in rats with CCl4-induced hepatic failure.. Pharmaceutical research, 17 ((7)): (833-838). [PMID:10990202]
11. In-Kyung Lee,Young-Mi Lee,Im-Sook Song,Suk-Jae Chung,Sang-Geon Kim,Myung-Gull Lee,Chang-Koo Shim. (2003-01-04) Hepatobiliary excretion of tributylmethylamonium in rats with lipopolysaccharide-induced acute inflammation.. Archives of pharmacal research, 25 ((6)): (969-972). [PMID:12510855]
12. D M Kou,J Qi. (2003-01-30) [Determination of carboxylic acid on a new capillary column prepared by ourselves].. Se pu = Chinese journal of chromatography, 17 ((6)): (550-552). [PMID:12552688]
13. Min-Koo Choi,Im-Sook Song,So-Ra Park,Soon-Sun Hong,Dae-Duk Kim,Suk-Jae Chung,Chang-Koo Shim. (2004-12-01) Mechanism of the stationary canalicular excretion of tributylmethyl ammonium in rats with a CCl4-induced acute hepatic injury.. Journal of pharmaceutical sciences, 94 ((2)): (317-326). [PMID:15570607]
14. Moon Kyoung Kim,Liwei Han,Min Koo Choi,Yong-Hae Han,Dae-Duk Kim,Suk-Jae Chung,Chang-Koo Shim. (2005-11-01) Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium.. Journal of pharmaceutical sciences, 94 ((12)): (2644-2655). [PMID:16258993]
15. Soon-Sun Hong,Sang-Cherl Moon,Chang-Koo Shim. (2006-05-10) Mechanism of intestinal transport of an organic cation, tributylmethylammonium in Caco-2 cell monolayers.. Archives of pharmacal research, 29 ((4)): (318-322). [PMID:16681038]
16. M K Choi,I S Song,D D Kim,S J Chung,C K Shim. (2007-10-24) Decreased biliary excretion of tributylmethyl ammonium in cholestyramine pretreated rats due to reduced formation of ion-pair complexes with hepatic bile salts.. Biopharmaceutics & drug disposition, 28 ((9)): (485-490). [PMID:17955510]
17. R W Van Dyke,E D Faber,D K Meijer. (1992-04-01) Sequestration of organic cations by acidified hepatic endocytic vesicles and implications for biliary excretion.. The Journal of pharmacology and experimental therapeutics, 261 ((1)): (1-11). [PMID:1348536]
18. J W Smit,B Weert,A H Schinkel,D K Meijer. (1998-07-10) Heterologous expression of various P-glycoproteins in polarized epithelial cells induces directional transport of small (type 1) and bulky (type 2) cationic drugs.. The Journal of pharmacology and experimental therapeutics, 286 ((1)): (321-327). [PMID:9655875]
19. I S Song,S J Chung,C K Shim. (2001-07-12) Contribution of ion pair complexation with bile salts to biliary excretion of organic cations in rats.. American journal of physiology. Gastrointestinal and liver physiology, 281 ((2)): (G515-G525). [PMID:11447032]
20. Im-Sook Song,In-Kyoung Lee,Suk-Jae Chung,Sang-Geon Kim,Myung-Gull Lee,Chang-Koo Shim. (2003-01-04) Effect of nitric oxide on the sinusoidal uptake of organic cations and anions by isolated hepatocytes.. Archives of pharmacal research, 25 ((6)): (984-988). [PMID:12510858]
21. Soon-Sun Hong,Hong Li,Min-Koo Choi,Suk-Jae Chung,Chang-koo Shim. (2005-04-19) Effect of a new hepatoprotective agent, YH-439, on the hepatobiliary transport of organic cations (OCs): selective inhibition of sinusoidal OCs uptake without influencing glucose uptake and canalicular OCs excretion.. Archives of pharmacal research, 28 ((3)): (330-334). [PMID:15832822]
22. Soon-Sun Hong,Jong-Moon Choi,Hyo-Eon Jin,Chang-Koo Shim. (2006-05-10) Altered pharmacokinetics and hepatic uptake of TBuMA in ethynylestradiol-induced cholestasis.. Archives of pharmacal research, 29 ((4)): (323-327). [PMID:16681039]
23. Won-Sik Shim,Min-Koo Choi,In-Wha Kim,Tae-Sik Kwon,Im-Sook Song,Liwei Han,Dae-Duk Kim,Suk-Jae Chung,Chang-Koo Shim. (2008-05-16) Decreased secretory transport of a quarternary ammonium, TBuMA, across LLC-PK1 cells by the anionic kidney extract.. Archives of pharmacal research, 31 ((5)): (671-677). [PMID:18481027]
24. Sarah Köhler,Tim Liebert,Thomas Heinze. (2009-07-23) Ammonium-based cellulose solvents suitable for homogeneous etherification.. Macromolecular bioscience, 9 ((9)): (836-841). [PMID:19623581]

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Tributylmethylammonium chloride - 75 wt. % in H2O, high purity , CAS No.56375-79-2