Click Here for 5% Off Your First Aladdin Purchase!

Triglycidyl Isocyanurate - 98%, high purity , CAS No.2451-62-9

  • ≥98%
Item Number
T102749
Grouped product items
SKUSizeAvailabilityPrice Qty
T102749-25g
25g
In stock
$34.90
T102749-100g
100g
In stock
$77.90
T102749-250g
250g
In stock
$175.90
T102749-500g
500g
In stock
$231.90

Basic Description

SynonymsTriglycidyl isocyanurate|2451-62-9|1,3,5-Triglycidyl isocyanurate|1,3,5-tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione|Triglycidylisocyanurate|Tris(2,3-epoxypropyl) isocyanurate|Glycidyl isocyanurate|Tri(epoxypropyl)isocyanurate|Tris(2,3-epoxypropy
Specifications & Purity≥98%
Shipped InNormal
Product Description

Triglycidyl isocyanurate is a reagent used in the synthesis of N-Benzyl Metaxalone , which is a muscle relaxant used to relax muscles and relieve pain.

Associated Targets

ESR1 Tclin Estrogen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

VDR Tclin Vitamin D3 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SMN1 Tchem Survival motor neuron protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RXRA Tclin Retinoic acid receptor RXR-alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1H4 Tclin Bile acid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOB Tclin Amine oxidase [flavin-containing] B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HBB Tbio Hemoglobin subunit beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CGA Tbio Glycoprotein hormones alpha chain 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TP53 Tchem Cellular tumor antigen p53 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARD Tchem Peroxisome proliferator-activated receptor delta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CXCL8 Tchem Interleukin-8 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488182353
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488182353
IUPAC Name 1,3,5-tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione
INCHI InChI=1S/C12H15N3O6/c16-10-13(1-7-4-19-7)11(17)15(3-9-6-21-9)12(18)14(10)2-8-5-20-8/h7-9H,1-6H2
InChi Key OUPZKGBUJRBPGC-UHFFFAOYSA-N
Canonical SMILES C1C(O1)CN2C(=O)N(C(=O)N(C2=O)CC3CO3)CC4CO4
Isomeric SMILES C1C(O1)CN2C(=O)N(C(=O)N(C2=O)CC3CO3)CC4CO4
RTECS XZ1994900
PubChem CID 17142
Molecular Weight 297.26
Reaxy-Rn 765833

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

14 results found

Lot NumberCertificate TypeDateItem
G2418318Certificate of AnalysisMar 14, 2024 T102749
G2418319Certificate of AnalysisMar 14, 2024 T102749
A2306852Certificate of AnalysisAug 23, 2022 T102749
A2306939Certificate of AnalysisAug 23, 2022 T102749
A2306943Certificate of AnalysisAug 23, 2022 T102749
A2306945Certificate of AnalysisAug 23, 2022 T102749
A2306963Certificate of AnalysisAug 23, 2022 T102749
A2307042Certificate of AnalysisAug 23, 2022 T102749
A2307062Certificate of AnalysisAug 23, 2022 T102749
C2406039Certificate of AnalysisAug 23, 2022 T102749
B2223473Certificate of AnalysisNov 29, 2021 T102749
B2223483Certificate of AnalysisNov 29, 2021 T102749
B2223490Certificate of AnalysisNov 29, 2021 T102749
B2223502Certificate of AnalysisNov 29, 2021 T102749

more

Chemical and Physical Properties

Solubilityinsoluble in water,soluble in dimethylformamide.
Melt Point(°C)108°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS05,   GHS07
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H331:Toxic if inhaled

H373:Causes damage to organs through prolonged or repeated exposure

H412:Harmful to aquatic life with long lasting effects

H318:Causes serious eye damage

H317:May cause an allergic skin reaction

H340:May cause genetic defects

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

RTECS XZ1994900
Reaxy-Rn 765833

Related Documents

References

1. K Nishioka,M Ogasawara,C Asagami.  (1988-11-01)  Occupational contact allergy to triglycidyl isocyanurate (TGIC, Tepic)..  Contact dermatitis,  19  ((5)): (379-380).  [PMID:2976653]
2. J A Neidhart,D Derocher,M R Grever,E H Kraut,L Malspeis.  (1984-09-01)  Phase I trial of teroxirone..  Cancer treatment reports,  68  ((9)): (1115-1119).  [PMID:6478450]
3. G Atassi,P Dumont,U Fisher,M Zeidler,M Budnowski.  (1984-03-01)  Preclinical evaluation of the anti tumour activity of new epoxyde derivatives..  Cancer treatment reviews,  11 Suppl A  (99-110).  [PMID:6733721]
4. M M Ames,J S Kovach,J Rubin.  (1984-09-01)  Pharmacological characterization of teroxirone, a triepoxide antitumor agent, in rats, rabbits, and humans..  Cancer research,  44  ((9)): (4151-4156).  [PMID:6744326]
5. R Jolanki,L Kanerva,T Estlander,K Tarvainen.  (1994-01-01)  Concomitant sensitization to triglycidyl isocyanurate, diaminodiphenylmethane and 2-hydroxyethyl methacrylate from silk-screen printing coatings in the manufacture of circuit boards..  Contact dermatitis,  30  ((1)): (12-15).  [PMID:8156756]
6. J P McFadden,R J Rycroft.  (1993-04-01)  Occupational contact dermatitis from triglycidyl isocyanurate in a powder paint sprayer..  Contact dermatitis,  28  ((4)): (251-251).  [PMID:8508645]
7. W Wigger-Alberti,M Hofmann,P Elsner.  (1997-06-01)  Contact dermatitis caused by triglycidyl isocyanurate..  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society,  ((2)): (106-107).  [PMID:9153332]
8. P Piirilä,T Estlander,H Keskinen,R Jolanki,A Laakkonen,P Pfäffli,O Tupasela,M Tuppurainen,H Nordman.  (1997-05-01)  Occupational asthma caused by triglycidyl isocyanurate (TGIC)..  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology,  27  ((5)): (510-514).  [PMID:9179424]
9. N M Craven,M Bhushan,M H Beck.  (1999-02-03)  Sensitization to triglycidyl isocyanurate, epoxy resins and acrylates in a developmental chemist..  Contact dermatitis,  40  ((1)): (54-55).  [PMID:9928813]
10. U Erikstam,M Bruze,A Goossens.  (2001-01-13)  Degradation of triglycidyl isocyanurate as a cause of false-negative patch test reaction..  Contact dermatitis,  44  ((1)): (13-17).  [PMID:11156005]
11. E Silva,L Hernandez,B Quiñonez,L E Gonzalez,C Colasante.  (2004-02-26)  Selective amino acids changes in the medial and lateral preoptic area in the formalin test in rats..  Neuroscience,  124  ((2)): (395-404).  [PMID:14980389]
12. Martin Roff,David A Bagon,Helen Chambers,E Martin Dilworth,Nicholas Warren.  (2004-04-03)  Dermal exposure to dry powder spray paints using PXRF and the method of Dirichlet tesselations..  The Annals of occupational hygiene,  48  ((3)): (257-265).  [PMID:15059802]
13. John White.  (2004-08-05)  Determination of triglycidyl isocyanurate from powder coatings in occupational hygiene samples by gas chromatography with mass spectrometric detection..  The Annals of occupational hygiene,  48  ((6)): (555-563).  [PMID:15292038]
14. Sébastien Gagné,Marielle Carrier,Simon Aubin.  (2015-09-26)  Determination of triglycidyl isocyanurate from air samples by ultra-performance liquid chromatography coupled with coordination ion spray mass spectrometry..  Rapid communications in mass spectrometry : RCM,  29  ((10)): (913-918).  [PMID:26407305]
15. Yu Qi,Haiqing Song,Haihua Xiao,Gang Cheng,Bingran Yu,Fu-Jian Xu.  (2018-09-22)  Fluorinated Acid-Labile Branched Hydroxyl-Rich Nanosystems for Flexible and Robust Delivery of Plasmids..  Small (Weinheim an der Bergstrasse, Germany),  14  ((42)): (e1803061-e1803061).  [PMID:30238691]
16. E Bahsi,S Sagmak,B Dayi,O Cellik,Z Akkus.  (2019-07-12)  The evaluation of microleakage and fluoride release of different types of glass ionomer cements..  Nigerian journal of clinical practice,  22  ((7)): (961-970).  [PMID:31293262]
17. Kun Zhang,Yan Huang,Yin-Jing Shen,Lin-Feng Zhang,Shuang Ma,Ting-Ting Chen,Ziqiang Zheng,Shishen Zhang,Benxia Li.  (2021-01-18)  Imine bond transformation of a dynamic Sm(III) macrocycle-based chemosensor: The indirect approach for detecting cyanuric chloride..  Analytica chimica acta,  1144  (34-42).  [PMID:33453795]
18. C S Munro,C M Lawrence.  (1992-01-01)  Occupational contact dermatitis from triglycidyl isocyanurate in a powder paint factory..  Contact dermatitis,  26  ((1)): (59-59).  [PMID:1534738]
19. A Dooms-Goossens,R Bedert,M Vandaele,H Degreef.  (1989-09-01)  Airborne contact dermatitis due to triglycidylisocyanurate..  Contact dermatitis,  21  ((3)): (202-203).  [PMID:2791551]
20. A Hempel,N Camerman,A Camerman.  (1989-03-01)  Crystallographic resolution and crystal and molecular structures of stereoisomers of 1,3,5-triglycidyl-s-triazinetrione..  Journal of medicinal chemistry,  32  ((3)): (648-651).  [PMID:2918513]
21. C G Mathias.  (1988-07-01)  Allergic contact dermatitis from triglycidyl isocyanurate in polyester paint pigments..  Contact dermatitis,  19  ((1)): (67-68).  [PMID:2972516]
22. H Fischer,U Zeidler,M Budnowski,G Atassi,P Dumont,J Venditti,O C Yoder.  (1984-01-01)  Investigation of the antitumor activity of new epoxide derivatives. Part I: s-Triazinetrione derivatives..  Arzneimittel-Forschung,  34  ((5)): (543-547).  [PMID:6540567]
23. P Dombernowsky,B Lund,H H Hansen.  (1983-01-01)  Phase-I study of alpha-1,3,5-triglycidyl-s-triazinetrione (NSC 296934)..  Cancer chemotherapy and pharmacology,  11  ((1)): (59-61).  [PMID:6883626]
24. L Meuleman,A Goossens,C Linders,F Rochette,B Nemery.  (1999-08-12)  Sensitization to triglycidylisocyanurate (TGIC) with cutaneous and respiratory manifestations..  Allergy,  54  ((7)): (752-756).  [PMID:10442533]
25. Sarah Allmaras.  (2003-02-08)  Worker exposure to 1,3,5-triglycidyl isocyanurate (TGIC) in powder paint coating operations..  Applied occupational and environmental hygiene,  18  ((3)): (151-153).  [PMID:12573957]
26. Joaquín Sastre,Jerónimo Carnes,Manuela García del Potro,Luis Manso,Erika Aguado,Mar Fernández-Nieto.  (2010-08-19)  Occupational asthma caused by triglycidyl isocyanurate..  International archives of occupational and environmental health,  84  ((5)): (547-549).  [PMID:20717691]
27. W Anees,V C Moore,J S Croft,A S Robertson,P S Burge.  (2010-11-03)  Occupational asthma caused by heated triglycidyl isocyanurate..  Occupational medicine (Oxford, England),  61  ((1)): (65-67).  [PMID:21041841]
28. Jing-Ping Wang,Kai-Han Lin,Chun-Yen Liu,Ya-Chu Yu,Pei-Tsun Wu,Chien-Chih Chiu,Chun-Li Su,Kwun-Min Chen,Kang Fang.  (2013-08-21)  Teroxirone inhibited growth of human non-small cell lung cancer cells by activating p53..  Toxicology and applied pharmacology,  273  ((1)): (110-120).  [PMID:23954467]
29. Beatriz Melendez-Rodriguez,Sergio Torres-Giner,Abdulaziz Aldureid,Luis Cabedo,Jose M Lagaron.  (2019-07-07)  Reactive Melt Mixing of Poly(3-Hydroxybutyrate)/Rice Husk Flour Composites with Purified Biosustainably Produced Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate)..  Materials (Basel, Switzerland),  12  ((13)):   [PMID:31277419]

Solution Calculators