(Trimethylsilyl)diazomethane - 2.0 M in hexanes, high purity , CAS No.18107-18-1

2 Citations
  • 2.0 M in hexanes
Item Number
T140538
Grouped product items
SKUSizeAvailabilityPrice Qty
T140538-5ml
5ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$49.90
T140538-25ml
25ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$169.90
T140538-100ml
100ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$539.90
T140538-500ml
500ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,149.90
View related series
organosilicon Silicon compound

Basic Description

SynonymsQI98HQO8C4 | TMSD | AT38821 | trimethylsilyl diazomethane | trimethyl-silyl diazomethane | diazomethyltrimethyl silane | EN300-74206 | Trimethlsilyl diazomethane | (Diazomethyl)trimethylsilane | (diazomethyl)-trimethylsilane | Q1990988 | trimethylsilyldia
Specifications & Purity2.0 M in hexanes
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Product Description

Reactant for preparation of: &bull Macrolactam analogs of the natural product macrolide (-)-A26771B with improved metabolic stability and antibacterial activity &bull Aigialomycin D analogues as protein kinase inhibitors for cancer treatment &bull Unnatural α-amino acid derivatives containing gem-bisphosphonates via Michael addition reaction &bull Capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates &bull Stictamides A-C as matrix metallopeptidase 12 (MMP12) inhibitors with antitumor invasion activity &bull Endothelin converting enzyme (ECE) Inhibitors WS 75624A and WS 75624B via a cross-metathesis approach &bull Ent-kaurene derivatives as anti-inflammatory agents &bull Desmosdumotin C analogs as potent antitumor agents acting via activation of spindle assembly checkpoint &bull Imidazolo[2,1-b]benzothiazole derivatives as potential p53 inhibitors

Names and Identifiers

IUPAC Name diazomethyl(trimethyl)silane
INCHI InChI=1S/C4H10N2Si/c1-7(2,3)4-6-5/h4H,1-3H3
InChi Key ONDSBJMLAHVLMI-UHFFFAOYSA-N
Canonical SMILES C[Si](C)(C)C=[N+]=[N-]
Isomeric SMILES C[Si](C)(C)C=[N+]=[N-]
WGK Germany 3
PubChem CID 167693
Molecular Weight 114.22
Beilstein 1902903

Certificates

Certificate of Analysis(COA)

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28 results found

Lot NumberCertificate TypeDateItem
H2402581Certificate of AnalysisJul 18, 2024 T140538
H2402458Certificate of AnalysisJul 18, 2024 T140538
H2402457Certificate of AnalysisJul 18, 2024 T140538
F2429148Certificate of AnalysisApr 11, 2024 T140538
C2426372Certificate of AnalysisMar 08, 2024 T140538
C2426371Certificate of AnalysisMar 08, 2024 T140538
A2410386Certificate of AnalysisDec 28, 2023 T140538
A2410387Certificate of AnalysisDec 28, 2023 T140538
A2410388Certificate of AnalysisDec 28, 2023 T140538
A2410389Certificate of AnalysisDec 28, 2023 T140538
A2410390Certificate of AnalysisDec 28, 2023 T140538
A2410391Certificate of AnalysisDec 28, 2023 T140538
C2327311Certificate of AnalysisMar 10, 2023 T140538
J2330056Certificate of AnalysisMar 10, 2023 T140538
H2328053Certificate of AnalysisMar 10, 2023 T140538
C2327312Certificate of AnalysisMar 10, 2023 T140538
C2327310Certificate of AnalysisMar 10, 2023 T140538
C2327309Certificate of AnalysisMar 10, 2023 T140538
A2309424Certificate of AnalysisJul 04, 2022 T140538
G2214589Certificate of AnalysisJul 04, 2022 T140538
G2214590Certificate of AnalysisJul 04, 2022 T140538
G2214591Certificate of AnalysisJul 04, 2022 T140538
G2214592Certificate of AnalysisJul 04, 2022 T140538
A2309425Certificate of AnalysisJul 04, 2022 T140538
C2202637Certificate of AnalysisFeb 17, 2022 T140538
C2202629Certificate of AnalysisFeb 17, 2022 T140538
C2202610Certificate of AnalysisFeb 17, 2022 T140538
C2202607Certificate of AnalysisFeb 17, 2022 T140538

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Chemical and Physical Properties

SolubilityImmiscible with water. Miscible with organic solvents.
SensitivityHeat & Moisture & Light Sensitive.
Flash Point(°F)-9.4 °F
Flash Point(°C)-23 °C
Boil Point(°C)96°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS09,   GHS07,   GHS02
Signal Danger
Hazard Statements

H315:Causes skin irritation

H331:Toxic if inhaled

H373:Causes damage to organs through prolonged or repeated exposure

H411:Toxic to aquatic life with long lasting effects

H225:Highly Flammable liquid and vapor

H330:Fatal if inhaled

H350:May cause cancer

H370:Causes damage to organs

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P320:Specific treatment is urgent (see ... on this label).

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P203:Obtain, read and follow all safety instructions before use.

P318:if exposed or concerned, get medical advice.

P308+P316:IF exposed or concerned: Get emergency medical help immediately.

P332+P317:If skin irritation occurs: Get medical help.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

Citations of This Product

1. Zhang Yu, Zheng Jianzhi, Li Xijuan, Wu Ying, Zhang Ke.  (2023)  Stoichiometric Imbalance-promoted Step-growth Polymerization Based on Self-accelerating Three-component Reaction.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  39  (5): (822-828).  [PMID:15196461]
2. Chujun Liu, Yawen Guo, Bo Wang, Lan Chen, Kaizhou Xie, Chenggen Yang.  (2021)  Establishment and Validation of a GC–MS/MS Method for the Quantification of Penicillin G Residues in Poultry Eggs.  Foods,  10  (11): (2735).  [PMID:34829016]

References

1. Zhang Yu, Zheng Jianzhi, Li Xijuan, Wu Ying, Zhang Ke.  (2023)  Stoichiometric Imbalance-promoted Step-growth Polymerization Based on Self-accelerating Three-component Reaction.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  39  (5): (822-828).  [PMID:15196461]
2. Chujun Liu, Yawen Guo, Bo Wang, Lan Chen, Kaizhou Xie, Chenggen Yang.  (2021)  Establishment and Validation of a GC–MS/MS Method for the Quantification of Penicillin G Residues in Poultry Eggs.  Foods,  10  (11): (2735).  [PMID:34829016]

Solution Calculators