Tris(2-carboxyethyl)phosphine hydrochloride

Item Number
T755610
Grouped product items
SKUSizeAvailabilityPrice Qty
T755610-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

Basic Description

Specifications & PurityBioUltra, for electrophoresis, SDS-PAGE tested
Storage TempRoom temperature
Shipped InNormal
GradeBioUltra, for electrophoresis
Product Description

Tris(2-carboxyethyl) phosphine hydrochloride (TCEP.HCL ) is a useful reducing agent for Sulphur and nitrogen-containing compounds. TCEP.HCL and the resultant oxide are water-soluble. TCEP.HCL has electron-rich phosphorus and oxygen atoms to combine with various metals, including Rh, Ir, and Pd. It rapidly complexes with Rh and Ir in dioxane at ambient temperature. It reduces disulfide linkages in a range of peptides and proteins in biological disulfide.
Application:
TCEP.HCL has been used in various bioconjugation applications, both in vitro and in vivo, to tag proteins and live organisms with great effectiveness under mild physiological circumstances. TCEP.HCL is suitable for varied biological and synthetic applications. At an acidic pH, TCEP.HCL can be used to convert organic disulfides to thiols in water irreversibly.
Water soluble reagent, used for selective reduction of disulfides. More stable than DTT and useful in mass spectrometry applications.

Names and Identifiers

IUPAC Name 3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride
INCHI InChI=1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
InChi Key PBVAJRFEEOIAGW-UHFFFAOYSA-N
Canonical SMILES C(CP(CCC(=O)O)CCC(=O)O)C(=O)O.Cl
Isomeric SMILES C(CP(CCC(=O)O)CCC(=O)O)C(=O)O.Cl
WGK Germany 2
PubChem CID 2734570
UN Number 3261
Packing Group II
Molecular Weight 286.65
Beilstein 3724376
Reaxy-Rn 3724376

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityH 2 O: soluble
Refractive Indexn20/D 1.367
Melt Point(°C)177°C

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H314:Causes severe skin burns and eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P363:Wash contaminated clothing before reuse.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes.

P316:Get emergency medical help immediately.

WGK Germany 2
Reaxy-Rn 3724376
Class 8
Merck Index 9085

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Solution Calculators