TRIS Hydrochloride

Item Number
T755536
Grouped product items
SKUSizeAvailabilityPrice Qty
T755536-250g
250g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$102.90
T755536-500g
500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$186.90

Basic Description

Specifications & PurityUltra pure, ≥99%(T), useful in pH range 7.0-9.0
Useful PH Range7.0-9.0
Storage TempRoom temperature
Shipped InNormal
GradeUltra pure
Product Description

Absorbance (1.0 M, H2O, 260 nm):≤0.1.
Useful in the pH range of 7.0-9.0. Has a pKa of 8.1 at 25°C.
Widely used as a biological buffer (absorbance: <0.1 at 260 nm, 1.0 M, H2O). A 1.0 M solution in H2O has a pH range of 3.5-5.0 and a pKa of 8.3 at 20°C.
Application:

  • Effect of Organic Solvents on the Activity, Stability and Secondary Structure of asclepain cI, Using FTIR and Molecular Dynamics Simulations.: This study uses Tris hydrochloride as a buffer to assess the stability and structural changes in the asclepain cI enzyme, providing insights into enzyme applications in industrial and medical biotechnology (Origone et al., 2024).

  • Microencapsulation of Omeprazole by Lactobacillus acidophilus ATCC 4356 Surface Layer Protein and Evaluation of its Stability in Acidic Condition.: Research demonstrates the use of Tris hydrochloride buffer in stabilizing microencapsulated omeprazole, aimed at enhancing drug delivery in acidic environments (Mobarak Qamsari et al., 2020).

Names and Identifiers

IUPAC Name 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
INCHI InChI=1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
InChi Key QKNYBSVHEMOAJP-UHFFFAOYSA-N
Canonical SMILES C(C(CO)(CO)N)O.Cl
Isomeric SMILES C(C(CO)(CO)N)O.Cl
WGK Germany 1
PubChem CID 93573
Molecular Weight 157.6
Beilstein 3675235

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubilitywater: 500 mg/mL
Melt Point(°C)150-152°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

WGK Germany 1

Related Documents

Solution Calculators