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Trityl Chloride - 97%, high purity , CAS No.76-83-5

≥97%

CAS#: 76-83-5
Formula: C₁₉H₁₅Cl
Molecular Weight: 278.78
Beilstein Registry Number: 397363
EC Number: 200-986-4
MDL number: MFCD00000813
PubChem CID: 6456

Item Number

T106184

Grouped product items
SKU	Size	Availability	Price
T106184-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$9.90
T106184-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$27.90
T106184-250g	250g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$49.90
T106184-500g	500g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$79.90

View related series

Amino protection Deprotection Derivatization Protection

Basic Description

Synonyms	Triphenylmethyl chloride\|76-83-5\|Trityl chloride\|CHLOROTRIPHENYLMETHANE\|Triphenylchloromethane\|(chloromethanetriyl)tribenzene\|Methane, chlorotriphenyl-\|(chlorodiphenylmethyl)benzene\|Benzene, 1,1',1''-(chloromethylidyne)tris-\|[Chloro(diphenyl)methyl]benzen
Specifications & Purity	≥97%
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Product Description	Trityl chloride is a protecting reagent for amines, alcohols, and thiols.

Names and Identifiers

IUPAC Name	[chloro(diphenyl)methyl]benzene
INCHI	InChI=1S/C19H15Cl/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
InChi Key	JBWKIWSBJXDJDT-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)Cl
Isomeric SMILES	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)Cl
WGK Germany	3
RTECS	PA6450000
PubChem CID	6456
UN Number	3261
Packing Group	III
Molecular Weight	278.78
Beilstein	397363
Reaxy-Rn	397363

Certificates

Certificate of Analysis(COA)

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9 results found

Lot Number	Certificate Type	Date	Item
C2429764	Certificate of Analysis	Mar 09, 2024	T106184
D2407022	Certificate of Analysis	Mar 09, 2024	T106184
D2407024	Certificate of Analysis	Mar 09, 2024	T106184
C2401061	Certificate of Analysis	Mar 05, 2024	T106184
C2202338	Certificate of Analysis	Jan 17, 2022	T106184
C2202341	Certificate of Analysis	Jan 17, 2022	T106184
C2202348	Certificate of Analysis	Jan 17, 2022	T106184
C2202353	Certificate of Analysis	Jan 17, 2022	T106184
C2202354	Certificate of Analysis	Jan 17, 2022	T106184

Solubility

Soluble in Hexane: 20 mg/ml Insoluble in water. Soluble in chloroform, hexane, benzene, ether, acetone and tetrahydrofuran.

Sensitivity

Moisture & heat sensitive.

Boil Point(°C)

310°C

Melt Point(°C)

113°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H335:May cause respiratory irritation H314:Causes severe skin burns and eye damage
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P332+P317:If skin irritation occurs: Get medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	PA6450000
Reaxy-Rn	397363
Class	8

References

1. J S Davidson,I M Baumgarten,E H Harley. (1985-10-30) Inhibition of intercellular junctional communication in human fibroblasts by triphenylmethane, triphenylmethylchloride, tetraphenylboron and related compounds.. Biochimica et biophysica acta, 847 ((1)): (1-7). [PMID:3931694]
2. K Lal,S Ray. (1982-05-01) Chlorodecarboxylation of 17 beta-acetoxy-3-methoxy-9-oxo-9, 11-secoestra-1, 3, 5 (10)-trien-11-oic acid with lead tetraacetate and trityl chloride.. Steroids, 39 ((5)): (537-545). [PMID:7147285]
3. S J Harding,J H Jones,A N Sabirov,V V Samukov. (1999-10-03) Im-trityl protection of histidine.. Journal of peptide science : an official publication of the European Peptide Society, 5 ((8)): (368-373). [PMID:10507686]
4. Ryuichi Hasegawa,Mutsuko Hirata-Koizumi,Mika Takahashi,Eiichi Kamata,Makoto Ema. (2005-12-20) Comparative susceptibility of newborn and young rats to six industrial chemicals.. Congenital anomalies, 45 ((4)): (137-145). [PMID:16359494]
5. Vijayavitthal T Mathad,Satish Kumar,Kanwal Raj. (2006-11-28) Oxidation studies on Andrographolide.. Natural product research, 20 ((12)): (1053-1058). [PMID:17127657]
6. R Hasegawa,M Hirata-Koizumi,M Dourson,A Parker,A Hirose,S Nakai,E Kamata,M Ema. (2006-12-13) Pediatric susceptibility to 18 industrial chemicals: a comparative analysis of newborn with young animals.. Regulatory toxicology and pharmacology : RTP, 47 ((3)): (296-307). [PMID:17157422]
7. Salvatore Debonis, Dimitrios A Skoufias, Rose-Laure Indorato, François Liger, Bernard Marquet, Christian Laggner, Benoît Joseph, Frank Kozielski,. (2008-02-13) Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.. Journal of medicinal chemistry, 51 ((5)): ( 1115-1125 ). [PMID:18266314]
8. Itedale Namro Redwan,Morten Grøtli. (2012-07-20) Method for activation and recycling of trityl resins.. The Journal of organic chemistry, 77 ((16)): (7071-7075). [PMID:22809057]
9. Teng-Hao Chen, Ilya Popov, Watchareeya Kaveevivitchai, Yu-Chun Chuang, Yu-Sheng Chen, Olafs Daugulis, Allan J Jacobson, Ognjen Š Miljanić,. (2014-10-14) Thermally robust and porous noncovalent organic framework with high affinity for fluorocarbons and CFCs.. Nature communications, ( 5131-5131 ). [PMID:25307413]
10. Julius L Chen,Andrew L Hicks,Michael E Chernew. (2018-07-19) Prices for physician services in Medicare Advantage versus traditional Medicare.. The American journal of managed care, 24 ((7)): (341-344). [PMID:30020754]

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Trityl Chloride - 97%, high purity , CAS No.76-83-5

Basic Description

Associated Targets

KIF11 Tchem Kinesin-like protein KIF11 0 Activities