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TRV056 - 99%, high purity , CAS No.812644-79-4

  • ≥99%
Item Number
T648017
Grouped product items
SKUSizeAvailabilityPrice Qty
T648017-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$55.90
T648017-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$140.90
T648017-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$220.90

Basic Description

Specifications & Purity99%
Storage TempProtected from light,Argon charged,Desiccated,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists.

In Vitro

TRV056 is a “gain-of-function” ligand that have >10-fold greater allosteric coupling to Gq than AngII and is also more efficacious in stimulating cellular Gq-mediated signaling (e.g., IP1 generation). Compared to the endogenous ligand angiotensin II (AngII), “Gq-biased” AT1R agonists are more efficacious in stimulating Gq-mediated cellular signaling and in allosterically promoting Gq coupling. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Names and Identifiers

Molecular Weight 1103.23

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityH2O : 1.96 mg/mL (1.78 mM; ultrasonic and adjust pH to 2 with HCl)

Related Documents

Solution Calculators