Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
T129677-5mg | 5mg | In stock | $29.90 | |
T129677-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $49.90 | |
T129677-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 | |
T129677-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $229.90 |
Discover Tubastatin A HCl by Aladdin Scientific in ≥98% for only $53.90. Available - in Ligands at Aladdin Scientific. Potent HDAC6 inhibitor Tags: Apoptosis, Epigenetics.
Synonyms | Tubastatin A hydrochloride|Tubastatin A HCl|1310693-92-5|Tubastatin A (Hydrochloride)|UHCM2AYJVX|TSA HCl|N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide;hydrochloride|N-hydroxy-4-((2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b |
---|---|
Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Tubastatin A HCl is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
IUPAC Name | N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide;hydrochloride |
---|---|
INCHI | InChI=1S/C20H21N3O2.ClH/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25;/h2-9,25H,10-13H2,1H3,(H,21,24);1H |
InChi Key | LJTSJTWIMOGKRJ-UHFFFAOYSA-N |
Canonical SMILES | CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO.Cl |
Isomeric SMILES | CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO.Cl |
PubChem CID | 57336514 |
Molecular Weight | 371.86 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
G2430239 | Certificate of Analysis | May 22, 2024 | T129677 |
G2430275 | Certificate of Analysis | May 22, 2024 | T129677 |
E1716085 | Certificate of Analysis | Jan 14, 2023 | T129677 |
L2015067 | Certificate of Analysis | Oct 15, 2022 | T129677 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 3.72, Max Conc. mM: 10 with gentle warming |
---|---|
Sensitivity | Heat Sensitive |
Starting at $45.90