Tubastatin A TFA - ≥98%, high purity , CAS No.1239262-52-2

  • ≥98%
Item Number
T275224
Grouped product items
SKUSizeAvailabilityPrice Qty
T275224-1mg
1mg
In stock
$280.90
T275224-5mg
5mg
In stock
$988.90
T275224-25mg
25mg
In stock
$4,446.90
T275224-100mg
100mg
In stock
$16,005.90

Discover Tubastatin A TFA by Aladdin Scientific in ≥98% for only $280.90. Available - in Ligands at Aladdin Scientific. Potent, selective HDAC6 inhibitor Tags: .

Basic Description

Synonyms1239262-52-2 | N-Hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide 2,2,2-trifluoroacetate | Tubastatin A TFA | Tubastatin TFA salt | Tubastatin A (TFA) | N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide;2
Specifications & Purity≥98%
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
Product Description

Product Application:

Tubastatin A (trifluoroacetate salt) is a neuroprotective HDAC6 and HDAC8 inhibitor 

Names and Identifiers

IUPAC Name N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide;2,2,2-trifluoroacetic acid
INCHI InChI=1S/C20H21N3O2.C2HF3O2/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25;3-2(4,5)1(6)7/h2-9,25H,10-13H2,1H3,(H,21,24);(H,6,7)
InChi Key AVAOVICSJJIYRZ-UHFFFAOYSA-N
Canonical SMILES CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO.C(=O)(C(F)(F)F)O
Isomeric SMILES CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO.C(=O)(C(F)(F)F)O
PubChem CID 50898504
Molecular Weight 449.42

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
K2218809Certificate of AnalysisSep 15, 2023 T275224
K2218843Certificate of AnalysisSep 15, 2023 T275224
K2218855Certificate of AnalysisSep 15, 2023 T275224
K2218975Certificate of AnalysisSep 15, 2023 T275224

Chemical and Physical Properties

SolubilitySoluble in 1:10 DMSO:PBS(pH7.2) (~0.1 mg/mL), ethanol (~0.2 mg/mL), DMF (~5 mg/mL), and DMSO (~5 mg/mL).

Related Documents

References

1. Ding Y et al..  (2019)  Inhibition of HDAC6 expression decreases brain injury induced by APOE4 and Aß co-aggregation in rats..  Mol Med Rep,  20  (4): (3363-3370).  [PMID:31432127]
2. Hu JX et al..  (2022)  Macrophage migration inhibitory factor (MIF) acetylation protects neurons from ischemic injury..  Cell Death Dis,  13  (5): (466).  [PMID:35585040]

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