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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T126560-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $43.90 | |
T126560-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $193.90 | |
T126560-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $313.90 | |
T126560-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $484.90 | |
T126560-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $741.90 | |
T126560-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,039.90 |
Synonyms | TUG-770|1402601-82-4|3-(4-((2-(cyanomethyl)phenyl)ethynyl)-2-fluorophenyl)propanoic acid|3-[4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluorophenyl]propanoic acid|CHEMBL2386353|TUG770|3-(4-{[2-(Cyanomethyl)phenyl]ethynyl}-2-fluorophenyl)propanoic acid|3-(4-{2 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Description: |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of FFA1 receptor |
Product Description | TUG-770 is a potent, selective and orally active GPR40/FFA1 agonist with an EC50 of 6 nM for human FFA1. TUG-770 shows a high selectivity for FFA1 over FFA2, FFA3, FFA4, PPARγ, other receptors, transporters, and enzymes. TUG-770 can be uesd for type 2 diabetes research. TUG-770 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. |
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IUPAC Name | 3-[4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluorophenyl]propanoic acid |
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INCHI | InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23) |
InChi Key | KIZUBVPJNPVIIN-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C(C(=C1)CC#N)C#CC2=CC(=C(C=C2)CCC(=O)O)F |
Isomeric SMILES | C1=CC=C(C(=C1)CC#N)C#CC2=CC(=C(C=C2)CCC(=O)O)F |
PubChem CID | 66553168 |
Molecular Weight | 307.32 |
PubChem CID | 66553168 |
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ChEMBL Ligand | CHEMBL2386353 |
CAS Registry No. | 1402601-82-4 |
GPCRdb Ligand | TUG-770 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2408169 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408171 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408172 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408209 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408210 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408211 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408212 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408213 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408214 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408226 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408227 | Certificate of Analysis | Mar 25, 2024 | T126560 |
G2408228 | Certificate of Analysis | Mar 25, 2024 | T126560 |
Solubility | 25°C: DMSO |
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