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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T275451-5mg | 5mg | In stock | $68.90 | |
T275451-10mg | 10mg | In stock | $107.90 | |
T275451-25mg | 25mg | In stock | $243.90 | |
T275451-50mg | 50mg | In stock | $375.90 | |
T275451-100mg | 100mg | In stock | $642.90 |
Novel S1P3 receptor antagonist
Synonyms | TY-52156|934369-14-9|TY 52156|N-(4-chloroanilino)-N'-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidamide|TY52156|N-(4-chlorophenyl)-N'-(4-chlorophenylamino)-3,3-dimethyl-2-oxobutanamidine|N-(4-Chlorophenyl)-3,3-dimethyl-2-oxobutanimidic 2-(4-chlorophenyl) h |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Novel S1P3 receptor antagonist (Ki = 110 nM). It preferentially inhibits the S1P-induced increase inintracellular calcium in Chinese hamster ovary cells expressing S1P3 over cell expressing S1P1, S1P2, or S1P4. |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of S1P 3 receptor |
Note | Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Shipped at 4°C. Store at -20°C long term. Store In the Dark. Product description: TY-52156 is a potent and selective S1P3 receptor antagonist with a Ki value of 110 nM。 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | N-(4-chloroanilino)-N'-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidamide |
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INCHI | InChI=1S/C18H19Cl2N3O/c1-18(2,3)16(24)17(21-14-8-4-12(19)5-9-14)23-22-15-10-6-13(20)7-11-15/h4-11,22H,1-3H3,(H,21,23) |
InChi Key | XONRRGIRSGNWFP-UHFFFAOYSA-N |
Canonical SMILES | CC(C)(C)C(=O)C(=NC1=CC=C(C=C1)Cl)NNC2=CC=C(C=C2)Cl |
Isomeric SMILES | CC(C)(C)C(=O)C(=NC1=CC=C(C=C1)Cl)NNC2=CC=C(C=C2)Cl |
PubChem CID | 16046248 |
Molecular Weight | 364.27 |
PubChem CID | 16046248 |
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CAS Registry No. | 934369-14-9 |
GPCRdb Ligand | TY-52156 |
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Lot Number | Certificate Type | Date | Item |
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J2221748 | Certificate of Analysis | Aug 21, 2023 | T275451 |
J2221746 | Certificate of Analysis | Aug 21, 2023 | T275451 |
J2221747 | Certificate of Analysis | Aug 21, 2023 | T275451 |
J2221743 | Certificate of Analysis | Aug 21, 2023 | T275451 |
J2221738 | Certificate of Analysis | Aug 21, 2023 | T275451 |
Solubility | Soluble in DMSO to\xa075 mM and in\xa0Ethanol to\xa075 mM |
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