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TY-52156 - ≥98%, high purity , CAS No.934369-14-9, Antagonist of S1P 3 receptor

  • Moligand™
  • ≥98%
Item Number
T275451
Grouped product items
SKUSizeAvailabilityPrice Qty
T275451-5mg
5mg
In stock
$68.90
T275451-10mg
10mg
In stock
$107.90
T275451-25mg
25mg
In stock
$243.90
T275451-50mg
50mg
In stock
$375.90
T275451-100mg
100mg
In stock
$642.90

Novel S1P3 receptor antagonist

View related series
S1P3 receptor Antagonist

Basic Description

SynonymsTY-52156|934369-14-9|TY 52156|N-(4-chloroanilino)-N'-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidamide|TY52156|N-(4-chlorophenyl)-N'-(4-chlorophenylamino)-3,3-dimethyl-2-oxobutanamidine|N-(4-Chlorophenyl)-3,3-dimethyl-2-oxobutanimidic 2-(4-chlorophenyl) h
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsNovel S1P3 receptor antagonist (Ki = 110 nM). It preferentially inhibits the S1P-induced increase inintracellular calcium in Chinese hamster ovary cells expressing S1P3 over cell expressing S1P1, S1P2, or S1P4.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of S1P 3 receptor
NoteRefer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Shipped at 4°C. Store at -20°C long term. Store In the Dark.


Product description:

TY-52156 is a potent and selective S1P3 receptor antagonist with a Ki value of 110 nM。

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

S1PR3 Tclin Sphingosine 1-phosphate receptor 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-(4-chloroanilino)-N'-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidamide
INCHI InChI=1S/C18H19Cl2N3O/c1-18(2,3)16(24)17(21-14-8-4-12(19)5-9-14)23-22-15-10-6-13(20)7-11-15/h4-11,22H,1-3H3,(H,21,23)
InChi Key XONRRGIRSGNWFP-UHFFFAOYSA-N
Canonical SMILES CC(C)(C)C(=O)C(=NC1=CC=C(C=C1)Cl)NNC2=CC=C(C=C2)Cl
Isomeric SMILES CC(C)(C)C(=O)C(=NC1=CC=C(C=C1)Cl)NNC2=CC=C(C=C2)Cl
PubChem CID 16046248
Molecular Weight 364.27

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
J2221748Certificate of AnalysisAug 21, 2023 T275451
J2221746Certificate of AnalysisAug 21, 2023 T275451
J2221747Certificate of AnalysisAug 21, 2023 T275451
J2221743Certificate of AnalysisAug 21, 2023 T275451
J2221738Certificate of AnalysisAug 21, 2023 T275451

Chemical and Physical Properties

SolubilitySoluble in DMSO to\xa075 mM and in\xa0Ethanol to\xa075 mM

Related Documents

Solution Calculators