U-69593 - ≥99%, high purity , CAS No.96744-75-1, Agonist of κ receptor

Item Number

U275821

• Synonyms: U-69593|96744-75-1|U69593|U 69593|U 69,593|n-methyl-2-phenyl-n-[(5r,7s,8s)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]dec-8-yl]acetamide|J5S4K6TKTG|N-Methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide|[3H]U69593|DTXSID3046326|CHEBI:73357|N-meth
• Specifications & Purity: Moligand™, ≥99%
• Biochemical and Physiological Mechanisms: Potent, selective κ 1 -opioid receptor agonist (EC 50 = 80-109 nM). Active in vivo . Antinociceptive.
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of κ receptor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

U-69593 is a potent and selective κ1-opioid receptor agonist. U-69593 attenuates addictive agent-induced behavioral sensitization in the rat. U-69593 reduces anxiety and enhances spontaneous alternation memory in mice. U-69593 reduces calcium-dependent dialysate levels of dopamine and glutamate in the ventral striatum.