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U 92016A - ≥99%, high purity , CAS No.149654-41-1

≥99%

CAS#: 149654-41-1
Formula: C₁₉H₂₅N₃HCl
Molecular Weight: 331.88
PubChem CID: 56972129

Item Number

U337674

Grouped product items
SKU	Size	Availability	Price	Qty
U337674-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$237.90
U337674-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$902.90

a selective SR-1A agonist

Basic Description

Synonyms	U 92016A\|149654-41-1\|U-92016A\|U-92016A hydrochloride\|U92016A (hydrochloride)\|DSP36A348S\|U-92,016-A\|(R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-2-carbonitrile hydrochloride\|3H-Benz(E)indole-2-carbonitrile, 8-(dipropylamino)-6,7,8,9-tetrahydro-
Specifications & Purity	≥99%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	U 92016A is a selective SR-1A (5-HT1A receptor) agonist that displays high intrinsic activity (K\|i\|values are 0.4, 7.7 and 36 nM for 5-HT1A, SR-1D (5-HT1D) and D2 receptors respectively and > 1000 nM for 5-HT2, D1, α1 and α2 receptors). Produces hypotension, hypothermia and 5-HT behavioral syndrome following p.o. administration.

Associated Targets

CX3CR1 Tchem CX3C chemokine receptor 1 0 Activities

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GPR35 Tchem G-protein coupled receptor 35 0 Activities

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BRD4 Tchem Bromodomain-containing protein 4 0 Activities

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CDK2 Tchem Cyclin-dependent kinase 2 0 Activities

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FFAR4 Tchem Free fatty acid receptor 4 0 Activities

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FPR2 Tchem N-formyl peptide receptor 2 0 Activities

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FGFR3 Tclin Fibroblast growth factor receptor 3 0 Activities

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CSNK1D Tchem Casein kinase I isoform delta 0 Activities

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S1PR1 Tclin Sphingosine 1-phosphate receptor 1 0 Activities

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TRIM24 Tchem Transcription intermediary factor 1-alpha 0 Activities

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C5AR1 Tclin C5a anaphylatoxin chemotactic receptor 1 0 Activities

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BRPF1 Tchem Peregrin 0 Activities

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AURKA Tchem Aurora kinase A 0 Activities

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ADRB2 Tclin Beta-2 adrenergic receptor 0 Activities

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APLNR Tchem Apelin receptor 0 Activities

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ABL1 Tclin Tyrosine-protein kinase ABL1 0 Activities

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ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

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ADGRF1 Tbio Adhesion G-protein coupled receptor F1 0 Activities

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AGTR1 Tclin Type-1 angiotensin II receptor 0 Activities

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GSK3B Tclin Glycogen synthase kinase-3 beta 0 Activities

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GPR119 Tclin Glucose-dependent insulinotropic receptor 0 Activities

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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

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MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

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Names and Identifiers

IUPAC Name	(8R)-8-(dipropylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-2-carbonitrile;hydrochloride
INCHI	InChI=1S/C19H25N3.ClH/c1-3-9-22(10-4-2)16-7-5-14-6-8-19-18(17(14)12-16)11-15(13-20)21-19;/h6,8,11,16,21H,3-5,7,9-10,12H2,1-2H3;1H/t16-;/m1./s1
InChi Key	XHLKAMFNZKKRFJ-PKLMIRHRSA-N
Canonical SMILES	CCCN(CCC)C1CCC2=C(C1)C3=C(C=C2)NC(=C3)C#N.Cl
Isomeric SMILES	CCCN(CCC)[C@@H]1CCC2=C(C1)C3=C(C=C2)NC(=C3)C#N.Cl
PubChem CID	56972129
Molecular Weight	331.88

Solubility

Soluble in water (10 mM), and DMSO (100 mM).

Refractive Index

n20D1.60 (Predicted)

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