UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC 50 of 12 nM
In Vivo
No toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Wild type mice derived from a Gpx4 fl/fl breeding Dosage: 20 µmol/kg Administration: Injected intraperitoneally; daily, over a period of 4 weeks Result: No toxicity was observed.