The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
UNC 2881 - ≥98%(HPLC), high purity , CAS No.1493764-08-1
Discover UNC 2881 by Aladdin Scientific in ≥98%(HPLC) for only $85.90. Available - in Ligands at Aladdin Scientific. Potent Mer kinase inhibitor Tags: .
Basic Description Synonyms UNC2881;2-(Butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamide Specifications & Purity ≥98%(HPLC) Storage Temp Store at -20°C Shipped In Dry ice Product Description Biochemical mechanism:
UNC2881 is a selective inhbitor of Mer kinase, a member of the TAM (Tyro3, Axl, Mer) receptor tyrosine kinase family. The IC50 values for inhibition of Mer, Axl and Tyro 3 are 4.3, 360 and 250 nM, respectively.
Names and Identifiers IUPAC Name 2-(butylamino)-4-[(4-hydroxycyclohexyl)amino]-N-[(4-imidazol-1-ylphenyl)methyl]pyrimidine-5-carboxamide INCHI InChI=1S/C25H33N7O2/c1-2-3-12-27-25-29-16-22(23(31-25)30-19-6-10-21(33)11-7-19)24(34)28-15-18-4-8-20(9-5-18)32-14-13-26-17-32/h4-5,8-9,13-14,16-17,19,21,33H,2-3,6-7,10-12,15H2,1H3,(H,28,34)(H2,27,29,30,31) InChi Key NPVXOWLPOFYACO-UHFFFAOYSA-N Canonical SMILES CCCCNC1=NC=C(C(=N1)NC2CCC(CC2)O)C(=O)NCC3=CC=C(C=C3)N4C=CN=C4 Isomeric SMILES CCCCNC1=NC=C(C(=N1)NC2CCC(CC2)O)C(=O)NCC3=CC=C(C=C3)N4C=CN=C4 PubChem CID 71721525 Molecular Weight 463.58
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 23.18, Max Conc. mM: 50
Safety and Hazards(GHS) RIDADR NONHforallmodesoftransport
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
J2130479