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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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U275196-1mg | 1mg | In stock | $18.90 | |
U275196-5mg | 5mg | In stock | $77.90 | |
U275196-10mg | 10mg | In stock | $116.90 | |
U275196-50mg | 50mg | In stock | $325.90 | |
U275196-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,467.90 |
Potent, selective and reversible G9 and GLP histone methyltransferase inhibitor
Synonyms | 1255580-76-7|UNC0638|UNC-0638|UNC 0638|2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine|1255517-77-1|2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine |
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Specifications & Purity | ≥98% |
Source | Synthetic |
Storage Temp | Store at -20°C,Desiccated |
Shipped In | Dry ice |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of euchromatic histone lysine methyltransferase 1;Inhibitor of euchromatic histone lysine methyltransferase 2 |
Product Description | Description |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine |
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INCHI | InChI=1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3H3,(H,31,32,33) |
InChi Key | QOECJCJVIMVJGX-UHFFFAOYSA-N |
Canonical SMILES | CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5 |
Isomeric SMILES | CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5 |
PubChem CID | 46224516 |
Molecular Weight | 509.73 |
PubChem CID | 46224516 |
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CAS Registry No. | 1255580-76-7 |
ChEMBL Ligand | CHEMBL1231795 |
RCSB PDB Ligand | CIQ |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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L2107128 | Certificate of Analysis | Jun 14, 2023 | U275196 |
L2107129 | Certificate of Analysis | Jun 14, 2023 | U275196 |
L2107132 | Certificate of Analysis | Jun 14, 2023 | U275196 |
L2107120 | Certificate of Analysis | Jun 14, 2023 | U275196 |
L2107152 | Certificate of Analysis | Jun 14, 2023 | U275196 |
Solubility | ≥25.5 mg/mL in DMSO; insoluble in H2O; ≥48.2 mg/mL in EtOH |
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