Urea crosslinker – C₂₋arm, NHS ester , CAS No.211029-82-2

Item Number
U486875
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U486875-50mg
50mg
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$192.90

Basic Description

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Product Description

Description

The ureido-2,2´-diacetic acid bis(hydroxysuccinimide) ester, is the shortest version of MS-cleavable urea-based lysine-lysine reactive homobifunctional cross-linkers, featuring a C2-arm. At neutral or slightly basic pH, it irreversibly crosslinks the neighbouring lysine groups. The presence of the symmetrical urea moiety which is prone to collision-induced dissociation, allows for the unambiguous distinguishing of crosslinks in tandem CID-MS experiments.

Names and Identifiers

IUPAC Name (2,5-dioxopyrrolidin-1-yl) 2-[[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethyl]carbamoylamino]acetate
INCHI InChI=1S/C13H14N4O9/c18-7-1-2-8(19)16(7)25-11(22)5-14-13(24)15-6-12(23)26-17-9(20)3-4-10(17)21/h1-6H2,(H2,14,15,24)
InChi Key VKVHTMGFAUCZIL-UHFFFAOYSA-N
Canonical SMILES C1CC(=O)N(C1=O)OC(=O)CNC(=O)NCC(=O)ON2C(=O)CCC2=O
PubChem CID 132282591
Molecular Weight 370.27

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