Uricase from Candida utilis - ≥2 units/mg dry weight, high purity , CAS No.9002-12-4

2 Citations
Item Number
U128546
Grouped product items
SKUSizeAvailabilityPrice Qty
U128546-100UN
100U
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$300.90
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酶类

Basic Description

SynonymsOxidase, urate | 9002-12-4 | azane;[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate | Uricase from Bacillus fastidiosus | VPXDHZMLJOJKOX-UHFFFAOYSA-N | FT-0686693 | FT
Specifications & Purity≥2 units/mg dry weight
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeEnzymoPure™
Product Description

Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.
Oxidizes uric acid

Names and Identifiers

Enzyme Commission Number1.7.3.3
Isomeric SMILES C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=CC(=O)NC4=O)CO)O)O.N
WGK Germany 3
RTECS YU7100000
PubChem CID 14228836

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4 results found

Lot NumberCertificate TypeDateItem
D2429469Certificate of AnalysisMar 14, 2024 U128546
D2429470Certificate of AnalysisMar 14, 2024 U128546
I2305219Certificate of AnalysisAug 15, 2023 U128546
D2230082Certificate of AnalysisMar 03, 2022 U128546

Safety and Hazards(GHS)

Pictogram(s) GHS08
Signal Danger
Hazard Statements

H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P501:Dispose of contents/container to ...

P284:[In case of inadequate ventilation] Wear respiratory protection.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

WGK Germany 3
RTECS YU7100000

Related Documents

Citations of This Product

1. Zheng Xinyu, Yang Yang, Gao Feng, Li Huihui, Yang Weikang, Guo Dong-Yu, Chen Shengming, Pan Qinhe.  (2022)  Enzyme-free fluorescence determination of uric acid by combining CdTe quantum dots with metal–organic framework for signal amplification.  MICROCHIMICA ACTA,  189  (11): (1-9).  [PMID:36318325]
2. Fuad Abduro Bushira, Shimeles Addisu Kitte, Yong Wang, Haijuan Li, Ping Wang, Yongdong Jin.  (2021)  Plasmon-Boosted Cu-Doped TiO2 Oxygen Vacancy-Rich Luminol Electrochemiluminescence for Highly Sensitive Detection of Alkaline Phosphatase.  ANALYTICAL CHEMISTRY,  93  (45): (15183–15191).  [PMID:34743510]

References

1. Zheng Xinyu, Yang Yang, Gao Feng, Li Huihui, Yang Weikang, Guo Dong-Yu, Chen Shengming, Pan Qinhe.  (2022)  Enzyme-free fluorescence determination of uric acid by combining CdTe quantum dots with metal–organic framework for signal amplification.  MICROCHIMICA ACTA,  189  (11): (1-9).  [PMID:36318325]
2. Fuad Abduro Bushira, Shimeles Addisu Kitte, Yong Wang, Haijuan Li, Ping Wang, Yongdong Jin.  (2021)  Plasmon-Boosted Cu-Doped TiO2 Oxygen Vacancy-Rich Luminol Electrochemiluminescence for Highly Sensitive Detection of Alkaline Phosphatase.  ANALYTICAL CHEMISTRY,  93  (45): (15183–15191).  [PMID:34743510]

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