Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab182778-100μg | 100μg | In stock | $109.90 | |
| Ab182778-1mg | 1mg | In stock | $519.90 | |
| Ab182778-5mg | 5mg | In stock | $1,399.90 | |
| Ab182778-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,239.90 |
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Vadastuximab (anti-CD33) - Primary antibody, specific to CD33, Human IgG1 |
|---|---|
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot |
| Specificity | CD33 |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description | Vadastuximab (anti-CD33) is a humanized monoclonal antibody targeting CD33. Vadastuximab (anti-CD33) can be used to synthesize an ADC compound, Vadastuximab talirine. Purity >95% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 27.0 kDa (Light Chain) & 52.8 kDa (Heavy Chain), under reducing conditions; 198.1 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 1436390-64-5 |
Vadastuximab (anti-CD33) (Ab182778) - Flow Cytometry
Flow Cytometry analysis of THP-1 cells labelling CD33 (red) with Vadastuximab (anti-CD33) (Ab182778). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Vadastuximab (anti-CD33) (Ab182778) - SEC
The purity of Vadastuximab (anti-CD33) (Ab182778) is more than 95% verified by HPLC.
Vadastuximab (anti-CD33) (Ab182778) - ELISA
Immobilized Recombinant Human Siglec-3/CD33 Protein (rp169578) at 1.0 μg/mL can bind Vadastuximab (anti-CD33) (Ab182778) with the EC₅₀ of 10.59 ng/mL.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0404828 | Certificate of Analysis | Apr 24, 2024 | Ab182778 |
| ZJ24F0404827 | Certificate of Analysis | Apr 24, 2024 | Ab182778 |
| ZJ24F0404826 | Certificate of Analysis | Apr 24, 2024 | Ab182778 |
