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Vancomycin HCL - USP grade,potency: ≥900 ug per mg, high purity , CAS No.1404-93-9

Specifications & Purity: USP grade,potency: ≥900 ug per mg

CAS#: 1404-93-9
Formula: C₆₆H₇₆Cl₃N₉O₂₄
Molecular Weight: 1485.71
Beilstein Registry Number: 3704657
PubChem CID: 6420023

Item Number

V105495

Grouped product items
SKU	Size	Availability	Price
V105495-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$19.90
V105495-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$49.90
V105495-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$139.90
V105495-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$399.90
V105495-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,119.90

Tricyclic glycopeptide antibiotic

Basic Description

Synonyms	Vancomycin HCL\|VANCOMYCIN HYDROCHLORIDE\|1404-93-9\|Vancomycin monohydrochloride\|Vancomycin, monohydrochloride\|Vancomycin, hydrochloride\|Firvanq\|Vancocin hydrochloride\|197638-25-8\|Vancomycin (as hydrochloride)\|71WO621TJD\|NSC-757377\|Vancocin hydrochloride in
Specifications & Purity	USP grade,potency: ≥900 ug per mg
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice

Names and Identifiers

IUPAC Name	(1S,2R,18R,19R,22S,25R,28R,40S)-48-[(2S,3R,4S,5S,6R)-3-[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[[(2R)-4-methyl-2-(methylamino)pentanoyl]amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid;hydrochloride
INCHI	InChI=1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1
InChi Key	LCTORFDMHNKUSG-XTTLPDOESA-N
Canonical SMILES	CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)C(CC(C)C)NC)O)Cl)CO)O)O)(C)N)O.Cl
Isomeric SMILES	C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O.Cl
WGK Germany	2
RTECS	YW4380000
PubChem CID	6420023
Molecular Weight	1485.71
Beilstein	3704657

Certificates

Certificate of Analysis(COA)

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9 results found

Lot Number	Certificate Type	Date	Item
J2327209	Certificate of Analysis	Oct 30, 2023	V105495
G2304033	Certificate of Analysis	Jul 07, 2023	V105495
L2319118	Certificate of Analysis	Jul 07, 2023	V105495
C2303160	Certificate of Analysis	Mar 07, 2023	V105495
A2309488	Certificate of Analysis	Jan 16, 2023	V105495
A2309413	Certificate of Analysis	Jan 13, 2023	V105495
G2225068	Certificate of Analysis	Aug 05, 2022	V105495
G2306129	Certificate of Analysis	Aug 05, 2022	V105495
K2306166	Certificate of Analysis	Aug 27, 2021	V105495

Chemical and Physical Properties

Solubility	Soluble in water. Slightly soluble in methanol, ethanol and dimethylsulfoxide.
Sensitivity	Hygroscopic

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315,H319,H335,H317
Precautionary Statements	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P272,P333+P313,P362+P364,P264+P265,P337+P317,P332+P317,P319
WGK Germany	2
RTECS	YW4380000

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Reviews

References

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59. Henry F Chambers. (2014-06-05) Pharmacology and the treatment of complicated skin and skin-structure infections.. The New England journal of medicine, 370 ((23)): (2238-2239). [PMID:24897088]
60. Vidya P Kumar,Chandrakala Basavannacharya,Sunita M de Sousa. (2014-06-20) A microplate assay for the coupled transglycosylase-transpeptidase activity of the penicillin binding proteins; a vancomycin-neutralizing tripeptide combination prevents penicillin inhibition of peptidoglycan synthesis.. Biochemical and biophysical research communications, 450 ((1)): (347-352). [PMID:24944023]
61. Darren N Seril,Bo Shen. (2014-07-06) Clostridium difficile infection in patients with ileal pouches.. The American journal of gastroenterology, 109 ((7)): (941-947). [PMID:24989088]
62. Ioannis M Zacharioudakis,Fainareti N Zervou,Panayiotis D Ziakas,Louis B Rice,Eleftherios Mylonakis. (2014-07-22) Vancomycin-resistant enterococci colonization among dialysis patients: a meta-analysis of prevalence, risk factors, and significance.. American journal of kidney diseases : the official journal of the National Kidney Foundation, 65 ((1)): (88-97). [PMID:25042816]
63. Filipe Cerca,Angela França,Begoña Pérez-Cabezas,Virgínia Carvalhais,Adília Ribeiro,Joana Azeredo,Gerald Pier,Nuno Cerca,Manuel Vilanova. (2014-07-24) Dormant bacteria within Staphylococcus epidermidis biofilms have low inflammatory properties and maintain tolerance to vancomycin and penicillin after entering planktonic growth.. Journal of medical microbiology, 63 ((Pt 10)): (1274-1283). [PMID:25053799]
64. Timothy P Hanrahan,Georgina Harlow,James Hutchinson,Joel M Dulhunty,Jeffrey Lipman,Tony Whitehouse,Jason A Roberts. (2014-08-02) Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis*.. Critical care medicine, 42 ((12)): (2527-2536). [PMID:25083977]
65. Jordan D Skelly,Jeffrey Lange,Tera M Filion,Xinning Li,David C Ayers,Jie Song. (2014-08-08) Vancomycin-bearing synthetic bone graft delivers rhBMP-2 and promotes healing of critical rat femoral segmental defects.. Clinical orthopaedics and related research, 472 ((12)): (4015-4023). [PMID:25099263]
66. Shannon L Russell,Matthew J Gold,Lisa A Reynolds,Benjamin P Willing,Pedro Dimitriu,Lisa Thorson,Stephen A Redpath,Georgia Perona-Wright,Marie-Renée Blanchet,William W Mohn,B Brett Finlay,Kelly M McNagny. (2014-08-26) Perinatal antibiotic-induced shifts in gut microbiota have differential effects on inflammatory lung diseases.. The Journal of allergy and clinical immunology, 135 ((1)): (100-109). [PMID:25145536]
67. Daniel J Morgan,Keith S Kaye,Daniel J Diekema. (2014-10-08) Reconsidering isolation precautions for endemic methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus.. JAMA, 312 ((14)): (1395-1396). [PMID:25291571]
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Vancomycin HCL - USP grade,potency: ≥900 ug per mg, high purity , CAS No.1404-93-9

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