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Vardenafil HCl Trihydrate - ≥98%, high purity , CAS No.330808-88-3
Basic Description
Synonyms | Vardenafil HCl Trihydrate | VARDENAFIL HYDROCHLORIDE [USP MONOGRAPH] | Levitra (TN) | Nuviva | VARDENAFIL HYDROCHLORIDE TRIHYDRATE [EP MONOGRAPH] | A816221 | 2-(2-ETHOXY-5-(4-ETHYL-PIPERAZINE-1-SULFONYL)-PHENYL)-5-METHYL-7-PROPYL-3H-IMIDAZO(5,1-F)(1,2,4)T |
Specifications & Purity | ≥98% |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Product Description | Vardenafil HCl Trihydrate is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively. |
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Names and Identifiers
IUPAC Name | 2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one;trihydrate;hydrochloride |
INCHI | InChI=1S/C23H32N6O4S.ClH.3H2O/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;;;;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);1H;3*1H2 |
InChi Key | FBCDRHDULQYRTB-UHFFFAOYSA-N |
Canonical SMILES | CCCC1=NC(=C2N1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C.O.O.O.Cl |
Isomeric SMILES | CCCC1=NC(=C2N1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C.O.O.O.Cl |
Alternate CAS | 224785-90-4,224785-91-5 |
PubChem CID | 135413545 |
Molecular Weight | 579.11 |
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Chemical and Physical Properties
Solubility | souble in water ;souble in Ether |
Sensitivity | Moisture sensitive.Air sensitive.Heat sensitive |
Citations of This Product
1. Ma Yufeng, Zhang Fengsen, Zhong Yijing, Huang Yongchun, Yixizhuoma , Jia Qiangqiang, Zhang Shoude. (2023) A label-free LC/MS-based enzymatic activity assay for the detection of PDE5A inhibitors. Frontiers in Chemistry, 11 [PMID:36860644] [10.3389/fchem.2023.1097027] |
References
1. Ma Yufeng, Zhang Fengsen, Zhong Yijing, Huang Yongchun, Yixizhuoma , Jia Qiangqiang, Zhang Shoude. (2023) A label-free LC/MS-based enzymatic activity assay for the detection of PDE5A inhibitors. Frontiers in Chemistry, 11 [PMID:36860644] [10.3389/fchem.2023.1097027] |
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